Large and small artery crosstalk in patients with type 2 diabetes

Background: Vascular complications to diabetes mellitus have, traditionally, been divided in to micro- and macroangiopathy. However, a growing body of evidence has put this categorical division into question, as large artery stiffness has been associated with microvascular complications in diabetics, e.g. diabetic retinopathy. The pathophysiology behind this association is poorly understood. The retinal arterioles lack sympathetic innervation and blood supply is autoregulated to accommodate changes in blood pressure and metabolic demand.

Source: Artery Research - November 25, 2016 Category: Cardiology Authors: Jonathan Mathias Baier, Esben Laugesen, S øren Tang Knudsen, Per Løgstrup Poulsen, Toke Bek Source Type: research