Quantifying heart and arterial contributions to central blood pressure in systole
Background: A recent study has shown that the central pressure waveform could be determined by a very small set of parameters accounting for the physical properties of the heart and the arteries [1]. Particularly, main pressure features like first systolic shoulder (P1) and systolic (P2) pressures were estimated accurately. (Source: Artery Research)
Source: Artery Research - November 25, 2016 Category: Cardiology Authors: Samuel Vennin, Ye Li, Marie Willemet, Henry Fok, Brian Clapp, Jordi Alastruey, Phil Chowienczyk Source Type: research
Diurnal changes in central pressure and pulse wave parameters in healthy subjects
Purpose: The feasibility of pulse wave analysis (PWA) over 24 hours with oscillometric devices has already been shown and first studies indicate additional information compared to single measurements. Nevertheless, diurnal patterns of PWA parameters in healthy subjects, which can potentially serve as a reference, are currently missing. Therefore, the aim of this study was to perform 24h-PWA measurements in healthy subjects over a wide age range and to analyse day/night differences. (Source: Artery Research)
Source: Artery Research - November 25, 2016 Category: Cardiology Authors: Bernhard Hametner, Christopher Mayer, Jelena K öster, Johannes Weber, Michael Reppel, Klaas Franzen, Eugenijus Kaniusas, Siegfried Wassertheurer, Kai Mortensen Source Type: research
Hemodynamics during intra- and interdialytic periods depend on ultrafiltration volume
Introduction: Parameters of arterial stiffness are independent cardiovascular risk factors for end-stage renal disease patients. Significant changes of these parameters between intra- and interdialytic periods have been reported previously [1]. The aim of this cross-sectional study is to describe the influence of the ultrafiltration volume on hemodynamic parameters. (Source: Artery Research)
Source: Artery Research - November 25, 2016 Category: Cardiology Authors: Christopher Mayer, Stephan Geilert, Julia Matschkal, Uwe Heemann, Marcus Baumann, Christoph Schmaderer Source Type: research
Aerobic fitness level and peripheral arterial compliance – the role of autonomic nervous system tone
Physical activity has beneficial effects on prevention of cardiovascular disease. Aerobic fitness is associated with higher central arterial compliance, but its effect on peripheral arterial compliance (pC) is controversial. We aimed to test the hypotheses that aerobic training augments pC at rest and during different autonomic nervous system provocations (ANSP) inyoung healthy men. (Source: Artery Research)
Source: Artery Research - November 25, 2016 Category: Cardiology Authors: Nejka Potocnik, Ziva Melik, Ksenija Cankar, Martin Strucl Source Type: research
Changes in cardiac function but not structure in healthy subjects with premature vascular ageing
Purpose: Changes in myocardial and arterial wall properties/function are consistently reported in patients with established cardiovascular disease1. However, few studies have reported these changes in early subclinical disease. The aim of the present study was to examine cardiac and vascular changes in early subclinical disease and to determine whether these changes occur in parallel. (Source: Artery Research)
Source: Artery Research - November 25, 2016 Category: Cardiology Authors: Oscar Mac Ananey, Vincent Maher Source Type: research
Sympathetic vasoconstrictor response to lower body negative pressure in young obese adults: the preliminary finding
Background: Elevations in muscle sympathetic nerve activity (MSNA) and sympathetic vasoconstrictor responsiveness to sympathoexcitation are associated with increased cardiovascular risks, which affect hemodynamics, and have been reported in obese adults with metabolic syndrome (1-3). It remains unclear whether this observation may also be present in young metabolically healthy obese adults. (Source: Artery Research)
Source: Artery Research - November 25, 2016 Category: Cardiology Authors: Kanokwan Bunsawat, Georgios Grigoriadis, Bo Fernhall, Tracy Baynard Source Type: research
Reduction in myocardial wall stress and delayed myocardial relaxation during exercise
The objective of this study was to examine the effect of exercise on time-varying MWS (3). (Source: Artery Research)
Source: Artery Research - November 25, 2016 Category: Cardiology Authors: Haotian Gu, Xiaoli Zhang, Benyu Jiang, Sally Brett, Phil Chowienczyk Source Type: research
Brachial artery flow-mediated dilatation: different patterns of wall shear rate increase during reactive hyperaemia
Background: Wall shear rate (WSR) is considered an important stimulus for flow-mediated dilatation (FMD). However, its estimation by conventional ultrasound is challenging due to inherent difficulties of velocity estimation near the arterial wall. To evaluate how WSR influences brachial artery FMD, we used a prototype Doppler ultrasound system which provides simultaneous estimates of WSR at near and far walls and continuous arterial diameter tracking. (Source: Artery Research)
Source: Artery Research - November 25, 2016 Category: Cardiology Authors: Kunihiko Aizawa, Sara Sbragi, Alessandro Ramalli, Piero Tortoli, Francesco Casanova, Carmela Morizzo, Clare Thorn, Angela Shore, Phillip Gates, Carlo Palombo Source Type: research
Cardio-ankle vascular index and carotid-femoral pulse wave velocity are closely associated with chronological age
Background: Vascular stiffening is part of the ageing process. However, it is not clear which vascular stiffness parameters are closely associated with chronological age. (Source: Artery Research)
Source: Artery Research - November 25, 2016 Category: Cardiology Authors: L.B. Mendes, E. Bunting, K. Ali, J. Timeyin, C. Rajkumar Source Type: research
Ultrasound characterization of cardiovascular alterations in young ob/ob mice
Obesity is associated with diabetes and an increased cardiovascular risk. Leptin-deficient mice (ob/ob) are used as model of metabolic disease: they are characterized by obesity and insulin-resistance. Aim of this work is to identify early cardiovascular alterations in young ob/ob mice using micro-ultrasound imaging. (Source: Artery Research)
Source: Artery Research - November 25, 2016 Category: Cardiology Authors: Nicole Di Lascio, Claudia Kusmic, Francesco Stea, Francesco Faita Source Type: research
Deletion of chromosome 9P21 noncoding cardiovascular risk interval in mice induces a prothrombotic phenotype
Background: SNPs on chromosome 9p21.3 risk locus have been associated with cardiovascular diseases. We have established a direct mechanistic link between 9p21 noncoding risk interval and susceptibility to aneurysm in a mouse model with a targeted deletion of the 9p21 noncoding cardiovascular disease risk interval. (Source: Artery Research)
Source: Artery Research - November 25, 2016 Category: Cardiology Authors: Amel Mohamadi, Mustapha Bourhim, Gemma Basatemur, Huguette Louis, Athanase Benetos, Patrick Lacolley, Ziad Mallat, Veronique Regnault Source Type: research
Functional aortic changes induced by a high salt diet
This study examines effects of high salt diet on arterial blood pressure and aortic function in rats. (Source: Artery Research)
Source: Artery Research - November 25, 2016 Category: Cardiology Authors: Kathleen Connolly, Mark Butlin, Bart Spronck, Carmel McEniery, Alberto Avolio, Ian Wilkinson Source Type: research
Evolution of cardiac function and metabolism during aging in a murine animal model of obesity
The objectives of this experimental study were to assess the effects of a long-term high fat diet (HFD) on metabolism, adipose tissues and phenotypes of cardiovascular aging. (Source: Artery Research)
Source: Artery Research - November 25, 2016 Category: Cardiology Authors: Delphine Lambert, Fatiha Maskali, Sylvain Poussier, Alexandra Clement, Jean-Loup Machu, Pierre-Yves Marie, Patrick Lacolley, Athanase Benetos, Laure Joly Source Type: research
Coagulation control by the RhoA pathway and the exchange factor Arhgef1
The objective was to study the RhoA pathway and its control by Arhgef1 in platelet aggregation and thrombin generation due to PAR receptor activation by thrombin. (Source: Artery Research)
Source: Artery Research - November 25, 2016 Category: Cardiology Authors: Camille Rouillon, Amel Mohammadi, Gervaise Loirand, Veronique Regnault, Patrick Lacolley Source Type: research
Ventricular volume and arterial flow during preload reduction: an MRI study
Lower body negative pressure (LBNP) has been used to assess the cardiovascular effect of preload reduction. We are the first to use MRI to investigate ventricular volumes and great vessel flow during LBNP. (Source: Artery Research)
Source: Artery Research - November 25, 2016 Category: Cardiology Authors: Sandra Neumann, Gergely Szantho, Emma C. Hart, Nathan E. Manghat, Mark S. Turner, Mark C.K. Hamilton Source Type: research
