High PWV is associated with nano-scale changes in the medial layer of the internal mammary artery

Background: Arterial stiffening occurs as part of the natural ageing process. Degradation of the extracellular matrix (ECM) in the medial layer is typically implicated in arterial stiffening. However, little is known about how localised changes in arteries in terms of both structure and mechanical properties contribute to the overall stiffening of arteries.

Source: Artery Research - November 25, 2016 Category: Cardiology Authors: Riaz Akhtar, Zhuo Chang, Maria Lyck Hansen, Lars Melholt Rasmussen Source Type: research