Hemodynamics of pulmonary hypertension: Application of the reservoir-wave approach

Using the reservoir-wave approach, previously we characterized pulmonary vasculature mechanics with multiple interventions in a canine model. In the present study, we measured high-fidelity pulmonary arterial (PA) pressure, Doppler flow velocity, and pulmonary capillary wedge pressure in 11 patients referred for evaluation of exertional dyspnea. The analysis was performed using the reservoir-wave approach; wave intensity analysis was subsequently utilized to characterize the PA wave pattern. Our objective was to identify specific abnormalities associated with pulmonary hypertension.

Source: Artery Research - November 24, 2015 Category: Cardiology Authors: Anukul Ghimire, Mads Andersen, Lindsay Burrowes, J. Christopher Bouwmeester, Andrew Grant, Israel Belenkie, Nowell Fine, Barry Borlaug, John Tyberg Source Type: research