Matrix Gla Protein in relation to left ventricular diastolic function

Introduction: Matrix Gla Protein (MGP) is highly expressed in cardiomyocytes and is upregulated after acute and chronic pressure overload and in myocardial hypertrophy in mice and humans. However, no study addressed the relation between cardiac function and MGP in humans.

Source: Artery Research - November 24, 2015 Category: Cardiology Authors: Thibault Petit, Zhen-Yu Zhang, Wen-Yi Yang, Fang-Fei Wei, Yu-Mei Gu, Juditha Knez, Nicholas Cauwenberghs, Yan-Ping Liu, Nadja Drummen, Lotte Jacobs, Lutgarde Thijs, Tatiana Kuznetsova, Stefan Janssens, Cees Vermeer, Jan A. Staessen Source Type: research