Retinal arteriolar structure in primary hypertension – Review of the data

Vascular dysfunction and remodelling due to elevated blood pressure constitutes an early step in the pathogenesis of atherosclerotic disease. Microvascular remodelling reduces tissue perfusion and impedes blood-tissue exchange. These processes could lead to inadequate perfusion and tissue hypoxia in situations of high metabolic demand. Impaired tissue perfusion may be involved in target-organ damage and complications that involve several vascular beds.
Source: Artery Research - Category: Cardiology Authors: Source Type: research