Age and hypertension strongly reduce aortic visco-elastic properties in rats at basal and matched blood pressure levels

Age and hypertension are major causes of large artery stiffening, a cardiovascular risk factor for heart and kidney damage. Long term hypertension induces vascular remodeling, accelerating vascular aging. The aged Spontaneously Hypertensive Rat (SHR) model is recognized for human cardiovascular pathology but discrepancies are apparent in studies of arterial stiffness.
Source: Artery Research - Category: Cardiology Authors: Source Type: research