Scandiatransplant acceptable mismatch program (STAMP) a bridge to transplanting highly immunized patients
ConclusionThe program has matured during the years and now proves to be a valid approach for transplanting highly immunized patients. (Source: Tissue Antigens)
Source: Tissue Antigens - April 28, 2017 Category: Allergy & Immunology Authors: P. Koefoed ‐Nielsen, I. Weinreich, M. Bengtsson, J. Lauronen, C. Naper, M. Gäbel, S. S. Sørensen, L. Wennberg, A. V. Reisæter, B. K. Møller, Tags: ORIGINAL ARTICLE Source Type: research
Detection of a new
HLA ‐B*44 allele,
HLA‐B*44:02:45, by monoallelic Sanger sequencing
Sequence of the novel allele,
HLA‐B*44:02:45, differs from
HLA‐B*44:02:01:01 by 1‐nucleotide exchange in exon 2. (Source: Tissue Antigens)
Source: Tissue Antigens - April 24, 2017 Category: Allergy & Immunology Authors: E. Kuzmich, O. Makarenko, A. Alyanskiy, B. Afanasyev Tags: NEW ALLELE ALERTS Source Type: research
Identification of the novel HLA ‐B*27:147 allele by polymerase chain reaction sequence‐based typing
HLA‐B*27:147 differs from HLA‐B*27:04:01 by a single nucleotide substitution at position 523 C>G. (Source: Tissue Antigens)
Source: Tissue Antigens - April 20, 2017 Category: Allergy & Immunology Authors: J. He, W. Zhang, Z. ‐D. Han, W. Wang, F.‐M. Zhu Tags: NEW ALLELE ALERTS Source Type: research
Identification of a new HLA ‐DQB1*06 allele, HLA‐DQB1*06:210, by monoallelic Sanger sequencing
Sequence of the novel allele, HLA‐DQB1*06:210, differs from HLA‐DQB1*06:03:01 by 1 nucleotide exchange in exon 2. (Source: Tissue Antigens)
Source: Tissue Antigens - April 19, 2017 Category: Allergy & Immunology Authors: E. Kuzmich, A. Nasredinova, A. Alyanskiy, B. Afanasyev Tags: NEW ALLELE ALERTS Source Type: research
An HLA ‐B7‐specific antibody in an
HLA‐B*07 positive patient explained by a nonexpressed allele (HLA‐B*07:181N)
Antibody identification by a bead array assay in a kidney patient revealed several HLA‐specific antibodies including one directed against the HLA‐B7 antigen. Low‐resolution typing of the patient indicated the presence of an
HLA‐B*07 allele. To rule out an HLA‐specific autoantibody the HLA‐typing of the patient was further refined by nucleotide sequencing on a next‐generation sequencing platform and eventually showed an
HLA‐B*39:01:01:03 and
HLA‐B*07:181N
genotype. Thereby the allospecific nature of the antibody was proven. The HLA‐B7‐specific antibody could be explained by an immunization during t...
Source: Tissue Antigens - April 18, 2017 Category: Allergy & Immunology Authors: S. Wenda, I. Fa é, G. F. Fischer Tags: BRIEF COMMUNICATIONS Source Type: research
A novel HLA ‐B allele: HLA‐B*40:242
The HLA‐B*40:242 allele differs from B*40:54 by 1 nucleotide substitution at position 190. (Source: Tissue Antigens)
Source: Tissue Antigens - April 12, 2017 Category: Allergy & Immunology Authors: J. W. Zheng, J. H. Xie, Y. Sun, Y. Q. Jiang, D. Xiang Tags: NEW ALLELE ALERTS Source Type: research
Identification of the novel
HLA ‐DRB1*15:127 allele by polymerase chain reaction sequence‐based typing in a Chinese bone marrow donor
HLA‐DRB1*15:127 has 1 nucleotide change from
HLA‐DRB1*15:01:01:01 at position 308 C>G. (Source: Tissue Antigens)
Source: Tissue Antigens - April 11, 2017 Category: Allergy & Immunology Authors: J. ‐J. He, Z.‐D. Han, J. He, J. Xu, F.‐M. Zhu Tags: NEW ALLELE ALERTS Source Type: research
A new allele, HLA ‐A*03:275N
The novel allele HLA‐A*03:275N differs from HLA‐A*03:01:01:01 by 1 nucleotide substitutions in exon 2 (Source: Tissue Antigens)
Source: Tissue Antigens - April 6, 2017 Category: Allergy & Immunology Authors: M. Battarra, R. Condello, T. Galluccio, C. Stellitano, M. Andreani Tags: NEW ALLELE ALERTS Source Type: research
Defining the immunogenicity and antigenicity of HLA epitopes is crucial for optimal epitope matching in clinical renal transplantation
Transplantation of an human leukocyte antigen (HLA) mismatched graft can lead to the development of donor‐specific antibodies (DSA), which can result in antibody mediated rejection and graft loss as well as complicate repeat transplantation. These DSA are induced by foreign epitopes present on the mismatched HLA antigens of the donor. However, not all epitopes appear to be equally effective in their ability to induce DSA. Understanding the characteristics of HLA epitopes is crucial for optimal epitope matching in clinical transplantation. In this review, the latest insights on HLA epitopes are described with a special fo...
Source: Tissue Antigens - April 5, 2017 Category: Allergy & Immunology Authors: C. S. M. Kramer, D. L. Roelen, S. Heidt, F. H. J. Claas Tags: REVIEW ARTICLE Source Type: research
HLA ‐B*40:247, a novel
HLA‐B*40 variant, identified by sequence‐based typing in a Taiwanese individual
A one nucleotide replacement in codon 261 of
HLA‐B*40:01:01 results in a novel allele,
HLA‐B*40:247 (Source: Tissue Antigens)
Source: Tissue Antigens - April 5, 2017 Category: Allergy & Immunology Authors: C. L. Chang, C. Y. Lin Tags: NEW ALLELE ALERTS Source Type: research
The novel
KIR3DS1*083 allele identified in a southern Chinese Han individual
KIR3DS1*083 allele differs from the closest allele
KIR3DS1*01301 by 3 mutations in exon 4. (Source: Tissue Antigens)
Source: Tissue Antigens - April 5, 2017 Category: Allergy & Immunology Authors: Y. ‐P. Xu, S.‐X. Wang, S.‐Q. Gao, H.‐B. Zhang Tags: NEW ALLELE ALERTS Source Type: research
Identification of a novel HLA ‐A allele, HLA‐A*02:505, by sequence‐based typing in a patient with tuberculosis
The novel allele HLA‐A*02:505 was identified in a tuberculosis patient by human leukocyte antigen sequence‐based typing. (Source: Tissue Antigens)
Source: Tissue Antigens - April 5, 2017 Category: Allergy & Immunology Authors: W. ‐X. Li, G. Li, L. Yao, G. Shen, R. Yang, F.‐W. Qiu, Y. Ma Tags: NEW ALLELE ALERTS Source Type: research
Characterization of the novel HLA ‐A*32:95 allele, identified in the Republic of Kazakhstan
HLA‐A*32:95 differs from A*32:01:01 at nucleotide 28 in exon 2 from C to A. (Source: Tissue Antigens)
Source: Tissue Antigens - April 4, 2017 Category: Allergy & Immunology Authors: A. A. Turganbekova, R. I. Ramilyeva, D. K. Baimukasheva, Zh. K. Burkitbayev, S. A. Abdrakhmanova Tags: NEW ALLELE ALERTS Source Type: research
Detection of a novel HLA ‐B allele,
HLA‐B*39:119, in a Chinese individual
HLA‐B*39:119 allele differs from
HLA‐B*39:01:01:01 by a single nucleotide substitution at position 488. (Source: Tissue Antigens)
Source: Tissue Antigens - April 4, 2017 Category: Allergy & Immunology Authors: H. Yu, X. Ji, G. J. Ou, J. Wang, Q. Chen Tags: NEW ALLELE ALERTS Source Type: research
Full ‐length sequences of 2 HLA‐B alleles, B*48:03:01 and B*48:04:01, confirmed by cloning and sequencing
Full‐length sequences of
HLA‐B*48:03:01 and B*48:04:01, confirmed by cloning and sequencing in Chinese donors. (Source: Tissue Antigens)
Source: Tissue Antigens - April 3, 2017 Category: Allergy & Immunology Authors: Z. Li, H. ‐Y. Zou Tags: NEW ALLELE ALERTS Source Type: research
