Sequencing of the novel HLA ‐A*02:01:72 allele in a Chinese hematopoietic stem cell donor
HLA‐A*02:01:72 has one synonymous nucleotide change from HLA‐A*02:01:01:01 where 591 G is changed to A. (Source: Tissue Antigens)
Source: Tissue Antigens - October 21, 2017 Category: Allergy & Immunology Authors: X. Zhang, F. ‐Q. Lin, C. Wu, B. Zhang, J.‐P. Li Tags: NEW ALLELE ALERTS Source Type: research
The novel HLA ‐A*24:02 variant, HLA‐A*24:02:56, identified by sequencing in a Chinese individual
HLA‐A*24:02:56 differs from A*24:02:01:01 by one nucleotide change at position 795 from C to T. (Source: Tissue Antigens)
Source: Tissue Antigens - October 20, 2017 Category: Allergy & Immunology Authors: F. ‐Q. Lin, X. Zhang, B. Zhang, C. Wu, J.‐P. Li Tags: NEW ALLELE ALERTS Source Type: research
A novel allele, HLA ‐A*31:108, identified by sequence‐based typing in a Chinese individual
Summary
The HLA‐A*31:108 allele was found. (Source: Tissue Antigens)
Source: Tissue Antigens - October 14, 2017 Category: Allergy & Immunology Authors: Haoqiang Ding, Yingfeng Huang, Yangkai Chen, Xin Ye Tags: NEW ALLELE ALERTS Source Type: research
Description of four new HLA alleles in the Finnish population: A*03:283N, A*68:167, C*03:327, C*03:361
Summary statement
New HLA alleles found in the Finnish population: A*03:283N, A*68:167, C*03:327 and C*03:361 (Source: Tissue Antigens)
Source: Tissue Antigens - October 14, 2017 Category: Allergy & Immunology Authors: A Polvi, J Per äsaari, T Linjama, T Saarinen, S Koskela, CEM Voorter, T Jaatinen Tags: NEW ALLELE ALERTS Source Type: research
Identification of the novel HLA ‐B*57:91 allele, by Next Generation Sequencing in a Spanish individual
Summary
HLA‐B*57:91 differs from HLA‐B*57:01:01 by a single nucleotide substitution resulting in an amino acid change. (Source: Tissue Antigens)
Source: Tissue Antigens - October 14, 2017 Category: Allergy & Immunology Authors: E Enrich, E Campos, JL Caro ‐Oleas, MJ Herrero‐Mata, F Rudilla Tags: NEW ALLELE ALERTS Source Type: research
Identification of a novel allele, HLA ‐A*02:189, in a Chinese Han individual
HLA‐A*02:189 differs from HLA‐A*02:01:01:01 by a single substitution in exon 3 (846 G>T). (Source: Tissue Antigens)
Source: Tissue Antigens - October 10, 2017 Category: Allergy & Immunology Authors: Y. ‐P. Zhong, Z.‐R. Quan, H. Chen, S.‐Q. Gao Tags: NEW ALLELE ALERTS Source Type: research
Discovery of HLA ‐C*14:87, a novel HLA‐C*14 variant, in a Taiwanese individual
Abstract
One nucleotide substitution at residue 526 of the HLA‐C*14:15 results in a novel allele, HLA‐C*14:87 (Source: Tissue Antigens)
Source: Tissue Antigens - October 10, 2017 Category: Allergy & Immunology Authors: K. L. Yang, P. Y. Lin Tags: NEW ALLELE ALERTS Source Type: research
A novel HLA ‐B allele, HLA‐B*35:348, was identified by sequencing‐based typing
HLA‐B*35:348 has one nucleotide substitution, c.817G>C (GTG→CTG at codon 248) compared to B*35:01:01:01. (Source: Tissue Antigens)
Source: Tissue Antigens - October 10, 2017 Category: Allergy & Immunology Authors: W. ‐H. Ma, Y.‐Q. Wu, Z.‐H. Feng, S.‐T. Pang Tags: NEW ALLELE ALERTS Source Type: research
A novel HLA class II allele, HLA‐DRB1*04:01:17, identified in a Chinese volunteer donor for CMDP
Abstract
A total of 322 HLA‐DRB1*04 alleles have been identified until July 2017(1). HLA‐DRB1*04 is the most common HLA‐ DRB1 allele among North Chinese Han populations with the antigen frequency of 11.51% (2). The DRB1*04:05 , DRB1*04:06 and DRB1*04:01 alleles were well represented in Shandong Peninsula population with allele frequencies of 3.70%, 1.79% and 1.39% respectively (3). (Source: Tissue Antigens)
Source: Tissue Antigens - October 5, 2017 Category: Allergy & Immunology Authors: Z. ‐H. Feng, Z.‐X. Yang, W.‐H. Ma, S.‐T. Pang Tags: NEW ALLELE ALERTS Source Type: research
Issue Information
(Source: Tissue Antigens)
Source: Tissue Antigens - October 5, 2017 Category: Allergy & Immunology Tags: ISSUE INFORMATION Source Type: research
The novel HLA ‐B*08:183 allele identified by sequence‐based typing in a Caucasian leukemia patient
Abstract
HLA‐B*08:183 differs from HLA‐B*08:01:01 by a single substitution in exon 5. (Source: Tissue Antigens)
Source: Tissue Antigens - October 5, 2017 Category: Allergy & Immunology Authors: AA. Mostafa, M. Petrosenko, L. Stamm, K. Faisal, N Berka Tags: NEW ALLELE ALERTS Source Type: research
A novel HLA ‐A*02 allele, A*02:692, was identified by sequencing‐based typing
One nucleotide replacement at nucleotide 811 of HLA‐A*02: 01:01:01 results in a new allele, HLA‐A*02:692. (Source: Tissue Antigens)
Source: Tissue Antigens - October 5, 2017 Category: Allergy & Immunology Authors: Y. Zhu, B. Han, X. Chi, B. Hu, Z. Feng Tags: NEW ALLELE ALERTS Source Type: research
Identification of the novel allele, HLA ‐DRB1*09:30, by sequence‐based high resolution typing
HLA‐DRB1*09:30 shows a single nucleotide difference from DRB1*09:01:02 at nucleotide 250 (CGG‐>TGG). (Source: Tissue Antigens)
Source: Tissue Antigens - October 5, 2017 Category: Allergy & Immunology Authors: G. Ou, X. Ji, J. Wang, Z. Liu Tags: NEW ALLELE ALERTS Source Type: research
A novel multiplex polymerase chain reaction assay for detection of both HLA ‐A*31:01/HLA‐B*15:02 alleles, which confer susceptibility to carbamazepine‐induced severe cutaneous adverse reactions
HLA‐A*31:01 and HLA‐B*15:02 have been widely reported to confer genetic susceptibility to carbamazepine (CBZ)‐induced severe cutaneous adverse reactions (SCARs). Accordingly, the screening for these alleles has been highly recommended to prevent SCAR prior to introducing CBZ therapy. Although a number of methods are available for screening of HLA‐A*31:01 or HLA‐B*15:02 alleles separately, developing an assay that can detect both these alleles would be more clinically practical, cost‐effective and less time‐consuming. Therefore, in this study, a multiplex polymerase chain reaction (PCR) using TaqMan Probe was ...
Source: Tissue Antigens - October 2, 2017 Category: Allergy & Immunology Authors: D. V. Nguyen, C. Vidal, H. C. Chi, N. T. Q. Do, R. Fulton, J. Li, S. L. Fernando Tags: ORIGINAL ARTICLE Source Type: research
Identification of the novel allele, HLA ‐B*15:388, in a Chinese bone marrow donor
Summary statement
The novel allele HLA‐B*15:388, was identified in a Chinese bone marrow donor by sequence‐based typing. (Source: Tissue Antigens)
Source: Tissue Antigens - September 30, 2017 Category: Allergy & Immunology Authors: B. Han, Y. ‐L. Zhu, Q.‐M. Guo, S.‐T. Pang, Z.‐H. Feng Tags: NEW ALLELE ALERTS Source Type: research
