A new allele, HLA ‐DQA1*02:01:02
Abstract
The new allele HLA‐DQA1*02:01:02 differs from DQA1*02:01:01:01by C to T substitution in exon 2. (Source: Tissue Antigens)
Source: Tissue Antigens - September 1, 2017 Category: Allergy & Immunology Authors: T Galluccio, A Guagnano, G Stanglino, T Vicenza, M. Andreani Tags: NEW ALLELE ALERTS Source Type: research
HLA ‐B*67:01:03, a HLA novel allele, identified in a Chinese platelet donor
HLA‐B*67:01:03 has one synonymous nucleotide change from HLA‐B*67:01:02 at nucleotide 873 (codon 267 Proline). (Source: Tissue Antigens)
Source: Tissue Antigens - August 31, 2017 Category: Allergy & Immunology Authors: X. ‐F. Li, Y. Liu, X. Zhang, F.‐Q. Lin, J.‐P. Li Tags: NEW ALLELE ALERTS Source Type: research
Genomic sequences of two novel hla ‐c alleles, hla‐c*15:143 and hla‐c*07:109:02
Two novel HLA‐C alleles, C*07:109:02 and C*15:143, were characterized in two Spanish individuals. (Source: Tissue Antigens)
Source: Tissue Antigens - August 31, 2017 Category: Allergy & Immunology Authors: A. Balas, F. Garc ía‐Sánchez, R. Alenda, J. L. Vicario Tags: NEW ALLELE ALERTS Source Type: research
Identification of a new HLA ‐B*51:226 allele, in a Chinese bone marrow related donor
Abstract
HLA‐B*51:226 was initially identified in a Chinese related donor for stem cell transplantation (Source: Tissue Antigens)
Source: Tissue Antigens - August 28, 2017 Category: Allergy & Immunology Authors: Y. ‐N. Li, Z.‐H. Feng, W.‐H. Ma, H.‐Y. Wang Tags: NEW ALLELE ALERTS Source Type: research
Identification of a novel allele, HLA ‐A*02:01:131, by full‐length genomic sequencing
Summary
The HLA‐A*02:01:131 allele differs by a single nucleotide at codon 236 compared with HLA‐A*02:01:01:01. (Source: Tissue Antigens)
Source: Tissue Antigens - August 28, 2017 Category: Allergy & Immunology Authors: Y. Park, H. Kim, J. Im, C. E. Yoon, H. S. Kim Tags: NEW ALLELE ALERTS Source Type: research
HLA ‐A*33:74N, a novel HLA‐A*33 variant, identified by sequence‐based typing in a Taiwanese individual
Abstract
A one nucleotide replacement in codon 803 of HLA‐A*33:03:01 results in a novel allele, HLA‐A*33:74 N (Source: Tissue Antigens)
Source: Tissue Antigens - August 28, 2017 Category: Allergy & Immunology Authors: C. Y. Lin, C. L. Chang Tags: NEW ALLELE ALERTS Source Type: research
Sequence ‐based typing of a novel HLA‐DRB1 allele, HLA‐DRB1*14:32:03, in a Chinese individual
Abstract
HLA‐DRB1*14:32:03 has one synonymous nucleotide change from HLA‐DRB1*14:32:02 at nucleotide 303 (codon 72 Arginine). (Source: Tissue Antigens)
Source: Tissue Antigens - August 26, 2017 Category: Allergy & Immunology Authors: Jian ‐Ping Li, Xu Zhang, Feng‐Qiu Lin, Yan‐Hong Dong, Xiao‐Feng Li Tags: NEW ALLELE ALERTS Source Type: research
High ‐throughput next‐generation sequencing to genotype six classical HLA loci from 96 donors in a single MiSeq run
Abstract
Next Generation Sequencing (NGS) methods have been established as an efficient approach for HLA typing because unlike traditional Sanger sequencing, they provide unambiguous results at a reasonable cost. We previously developed a multi‐locus index method to genotype four HLA loci (A, B, C, and DRB1) on the Illumina MiSeq platform. We have now expanded this method to include two additional loci, HLA‐DPB1 and DQB1. Contiguous full‐length amplicons from 5’UTR through 3’UTR regions were generated using one long‐range PCR reaction per locus for each of the six loci from 96 individuals of different ethniciti...
Source: Tissue Antigens - August 25, 2017 Category: Allergy & Immunology Authors: Philip K. Ehrenberg, Aviva Geretz, Ravi Kumar Sindhu, Tamara Vayntrub, Marcelo A. Fern ández Viña, Richard Apps, Nelson Michael, Rasmi Thomas Tags: ORIGINAL ARTICLE Source Type: research
Sequence identification, serological reactivity and family genetics of a novel HLA alelle, HLA ‐A*26:82
HLA‐A*26:82 was identified by sequence‐based typing and showed the serological specificity of A26. (Source: Tissue Antigens)
Source: Tissue Antigens - August 24, 2017 Category: Allergy & Immunology Authors: C. Zhu, X. Nie, Y. Song, Y. Zhang, W. Qiao Tags: NEW ALLELE ALERTS Source Type: research
HLA ‐DPB1*519:01, a new allele identified by sequence‐based typing in a Korean individual
The new allele DPB1*519:01 showed one nucleotide difference with DPB1*13:01:01 at codon 234 (GTG/ATG). (Source: Tissue Antigens)
Source: Tissue Antigens - August 22, 2017 Category: Allergy & Immunology Authors: H. J. Choi, J. Im, J. H. Lee, S. H. Kim, M. G. Shin Tags: NEW ALLELE ALERTS Source Type: research
The full ‐length sequence of HLA‐B*59:01:01:01 confirmed by cloning and sequencing
The full‐length sequence of HLA‐B*59:01:01:01. (Source: Tissue Antigens)
Source: Tissue Antigens - August 15, 2017 Category: Allergy & Immunology Authors: Z. Li, H. ‐Y. Zou, D. Zhou Tags: NEW ALLELE ALERTS Source Type: research
ABO Blood Group Phenotype Frequency Estimation Using Molecular Phenotyping in Rhesus and Cynomolgus Macaques
This study underscores the importance of ABO blood group phenotyping of the domestic supply of macaques and their biospecimens. (Source: Tissue Antigens)
Source: Tissue Antigens - August 11, 2017 Category: Allergy & Immunology Authors: S. Kanthaswamy, J. Ng, R. Oldt, L. Valdivia, P. Houghton, D. G. Smith Tags: BRIEF COMMUNICATION Source Type: research
A variant of HLA‐DRB1*11, HLA‐DRB1*11:143, discovered in a Chinese hematopoietic stem cell donor
Abstract
HLA‐DRB1*11:143 has one nucleotide change from HLA‐DRB1*11:01:01 where Aspartic Acid (70) is changed to Glycine. (Source: Tissue Antigens)
Source: Tissue Antigens - August 10, 2017 Category: Allergy & Immunology Authors: Xiao ‐Feng Li, Gui‐Ji Li, Xu Zhang, Hua Fan, Jian‐Ping Li Tags: NEW ALLELE ALERTS Source Type: research
Detection of a novel HLA ‐DRB1*09 variant, HLA‐DRB1*09:31, in a College of American Pathologists HLA survey sample
Abstract
One nucleotide substitution at residue 25 of HLA‐DRB1*09:01:02:01 results in a novel allele, HLA‐DRB1*09:31. (Source: Tissue Antigens)
Source: Tissue Antigens - August 10, 2017 Category: Allergy & Immunology Authors: K. L. Yang, P. Y. Lin Tags: NEW ALLELE ALERTS Source Type: research
A novel analysis strategy for HLA typing using a sequence ‐specific oligonucleotide probe method
ConclusionThe FnS method showed improved accuracy and efficiency of HLA typing in a comprehensive and quantitative comparison between measured and expected CRPoAPs of candidate allele pairs. Therefore, this analysis strategy might be useful in a clinical setting. (Source: Tissue Antigens)
Source: Tissue Antigens - August 10, 2017 Category: Allergy & Immunology Authors: Dong Il Won Tags: ORIGINAL ARTICLE Source Type: research
