HLA ‐A*24:388N: a novel HLA‐A*24 allele identified by sequence‐based typing
Summary statement
The novel allele, A*24:388N, was identified by sequence‐based typing in a Chinese individual. (Source: Tissue Antigens)
Source: Tissue Antigens - September 30, 2017 Category: Allergy & Immunology Authors: Daoming Wang, Xiaoqin Yang, Xianghua Chai, Junbin Fang, Xiuqing Zhang Tags: NEW ALLELE ALERTS Source Type: research
A novel HLA ‐DRB1 allele, HLA‐DRB1*14:127:02, detected in a Chinese hematopoietic stem cell donor
HLA‐DRB1*14:127:02 has one nucleotide change from HLA‐DRB1*14:05:01 where Threonine (77) is changed to Asparagine. (Source: Tissue Antigens)
Source: Tissue Antigens - September 25, 2017 Category: Allergy & Immunology Authors: J. ‐P. Li, X. Zhang, F.‐Q. Lin, K.‐L. Zhang, X.‐F. Li Tags: NEW ALLELE ALERTS Source Type: research
Two novel alleles, HLA ‐A*02:643N and HLA‐B*53:44, identified in Brazilian individuals
Two novel alleles, HLA‐A*02:643N and HLA‐B*53:44, generated by different mechanisms, were identified in Brazilian individuals. (Source: Tissue Antigens)
Source: Tissue Antigens - September 23, 2017 Category: Allergy & Immunology Authors: E. M. G. Vale, E. Nascimento, C. K. F. Oliveira, M. F. Lasmar, R. A. Fabreti ‐Oliveira Tags: NEW ALLELE ALERTS Source Type: research
Identification of a new HLA ‐B*51:226 allele in a Chinese bone marrow‐related donor
HLA‐B*51:226 was initially identified in a Chinese‐related donor for stem cell transplantation. (Source: Tissue Antigens)
Source: Tissue Antigens - September 20, 2017 Category: Allergy & Immunology Authors: Y. ‐N. Li, Z.‐H. Feng, W.‐H. Ma, H.‐Y. Wang Tags: NEW ALLELE ALERTS Source Type: research
Candidate gene molecular markers as tools for analyzing genetic susceptibility to Morbillivirus infection in stranded Cetaceans
Abstract
Morbilliviruses, such as Cetacean morbillivirus (CeMV) or Phocine distemper virus (PDV), represent a growing threat for marine mammals on both hemispheres. Since free‐ranging animal populations strongly rely on natural resistance mechanisms, innate immunity related genes and virus cell entry receptor genes may represent key factors involved in susceptibility to CeMV in Cetaceans. Using the next generation sequencing technology, we have sequenced eleven candidate genes in two model species, Stenella coeruleoalba and Phocoena phocoena. Suitable single nucleotide polymorphism markers of potential functional importa...
Source: Tissue Antigens - September 11, 2017 Category: Allergy & Immunology Authors: Karla Stejskalova, Zuzana Bayerova, Jan Futas, Kristyna Hrazdilova, Marie Klumplerova, Jan Oppelt, Petra Splichalova, Giovanni Di Guardo, Sandro Mazzariol, Cristina Esmeralda Di Francesco, Gabriella Di Francesco, Giuliana Terracciano, Romulus ‐Marian Pa Tags: ORIGINAL ARTICLE Source Type: research
Characterization of the novel HLA ‐DRB1*13:241 allele by sequencing‐based typing
Abstract
HLA‐DRB1*13:241 differs from HLA‐DRB1*13:02:01 by one nucleotide substitution at position 335. (Source: Tissue Antigens)
Source: Tissue Antigens - September 8, 2017 Category: Allergy & Immunology Authors: Li ‐Qun Zhang, Xiao‐Yang Zhou, Yao Xiao, Jian‐Ping Cai Tags: NEW ALLELE ALERTS Source Type: research
Identification of HLA ‐B*58:01:21, a novel allele in a Korean individual
Abstract
Summary statement
B*58:01:21 has a single nucleotide change, c.264A>G (ACA→ACG at codon 88) compared to B*58:01:01:01. (Source: Tissue Antigens)
Source: Tissue Antigens - September 8, 2017 Category: Allergy & Immunology Authors: Jun Hyung Lee, Hyun ‐Jung Choi, Soo‐Hyun Kim, Myung‐Geun Shin Tags: NEW ALLELE ALERTS Source Type: research
HLA ‐B*40:302, a novel allele identified by sequence‐based typing in a Korean individual
Abstract
Summary statement:
B*40:302 differs from B*40:02:01:01 by a single non‐synonymous nucleotide substitution at codon 81 (CCG→CTG). (Source: Tissue Antigens)
Source: Tissue Antigens - September 8, 2017 Category: Allergy & Immunology Authors: Jun Hyung Lee, Jisu Im, Hyun ‐Jung Choi, Soo‐Hyun Kim, Myung‐Geun Shin Tags: NEW ALLELE ALERTS Source Type: research
Characterization of the novel HLA ‐A*02:07:10 allele by sequencing‐based typing
Abstract
HLA‐A*02:07:10 differs from HLA‐A*02:07:01 by one nucleotide substitution at position 117. (Source: Tissue Antigens)
Source: Tissue Antigens - September 8, 2017 Category: Allergy & Immunology Authors: Li ‐Qun Zhang, Xiao‐Yang Zhou, Yao Xiao, Jian‐Ping Cai Tags: NEW ALLELE ALERTS Source Type: research
Characterization of the novel HLA ‐DQB1*05:155 allele by sequencing‐based typing
Abstract
HLA‐DQB1*05:155 differs from HLA‐DQB1*05:01:01 by one nucleotide substitution at position 474 (G > C). (Source: Tissue Antigens)
Source: Tissue Antigens - September 8, 2017 Category: Allergy & Immunology Authors: Li ‐Qun Zhang, Xiao‐Yang Zhou, Yao Xiao, Jian‐Ping Cai Tags: NEW ALLELE ALERTS Source Type: research
A novel multiplex PCR assay for detection of both HLA ‐A*31:01/HLA‐B*15:02 alleles, which confer susceptibility to carbamazepine‐induced severe cutaneous adverse reactions
Abstract
HLA‐A*31:01 and HLA‐B*15:02 have been widely reported to confer genetic susceptibility to carbamazepine–induced severe cutaneous adverse reactions. Accordingly, the screening for these alleles has been highly recommended to prevent SCAR prior to introducing CBZ therapy. Although a number of methods are available for screening of HLA‐A*31:01 or HLA‐B*15:02 alleles separately, developing an assay that can detect both these alleles would be more clinically practical, cost‐effective and less time‐consuming. Therefore, in this study, a multiplex PCR using Taq°Man Probe was designed and validated to be ab...
Source: Tissue Antigens - September 8, 2017 Category: Allergy & Immunology Authors: Dinh Van Nguyen, Christopher Vidal, Hieu Chi Chu, Nga Thi Quynh Do, Richard Fulton, Jamma Li, Suran L Fernando Tags: ORIGINAL ARTICLE Source Type: research
Prof. Dr. Johannes Joseph van Rood (1926 ‐2017)
(Source: Tissue Antigens)
Source: Tissue Antigens - September 7, 2017 Category: Allergy & Immunology Authors: R. E. Bontrop, A. Brand, F. H. J. Claas Tags: OBITUARY Source Type: research
Issue Information
(Source: Tissue Antigens)
Source: Tissue Antigens - September 7, 2017 Category: Allergy & Immunology Tags: ISSUE INFORMATION Source Type: research
Sequence identification, serological reactivity and family genetics of a novel HLA allele, HLA ‐A*26:82
HLA‐A*26:82 was identified by sequence‐based typing and showed the serological specificity of A26. (Source: Tissue Antigens)
Source: Tissue Antigens - September 7, 2017 Category: Allergy & Immunology Authors: C. Zhu, X. Nie, Y. Song, Y. Zhang, W. Qiao Tags: NEW ALLELE ALERTS Source Type: research
A variant of HLA ‐DRB1*11, HLA‐DRB1*11:143, discovered in a Chinese hematopoietic stem cell donor
HLA‐DRB1*11:143 has one nucleotide change from HLA‐DRB1*11:01:01 where Aspartic Acid (70) is changed to Glycine. (Source: Tissue Antigens)
Source: Tissue Antigens - September 4, 2017 Category: Allergy & Immunology Authors: X. ‐F. Li, G.‐J. Li, X. Zhang, H. Fan, J.‐P. Li Tags: NEW ALLELE ALERTS Source Type: research
