A comprehensive mRNA expression analysis of developing chicken articular cartilage
Publication date: Available online 10 November 2015 Source:Gene Expression Patterns Author(s): Pratik Narendra Pratap Singh, Ayan Ray, Kimi Azad, Amitabha Bandyopadhyay Articular cartilage present at the ends of appendicular skeletal elements provides friction-less movement to the synovial joints and any damage to this tissue can lead to a degenerative disease of joint called osteoarthritis. During past two decades although many genes e.g.,Gdf5, Wnt9a, Noggin etc. have been identified and characterized in joint development, still a comprehensive understanding of molecular network(s) operational in articular car...
Source: Gene Expression Patterns - November 10, 2015 Category: Genetics & Stem Cells Source Type: research
Gene-expression profile of developing pollen tube of Pyrus bretschneideri
Publication date: Available online 4 November 2015 Source:Gene Expression Patterns Author(s): Hongsheng Zhou, Hao Yin, Jianqing Chen, Xing Liu, Yongbin Gao, Juyou Wu, Shaoling Zhang Pollen is an ideal model system for investigation of cell growth. In order to better understand the molecular biology mechanisms of the process of pear pollen tube development, RNA sequencing (RNA-Seq) technology was used to characterize the expression of genes during four development stages of pear pollen, including mature pollen grains (MP), hydrated pollen grains (HP), growing pollen tubes (PT) and stopped-growth pollen tub...
Source: Gene Expression Patterns - November 4, 2015 Category: Genetics & Stem Cells Source Type: research
Molecular Characterization of Myf5 and Comparative Expression Patterns of Myogenic Regulatory Factors in Siniperca Chuatsi
Publication date: Available online 4 November 2015 Source:Gene Expression Patterns Author(s): Xin Zhu, Yu-Long Li, Li Liu, Jian-Hua Wang, Hong-Hui Li, Ping Wu, Wu-Ying Chu, Jian-She Zhang Myogenic regulatory factors (MRFs) are muscle-specific basic helix–loop–helix (bHLH) transcription factor that plays an essential role in regulating skeletal muscle development and growth. To investigate molecular characterization of Myf5 and compare the expressional patterns of the four MRFs, we cloned the Myf5 cDNA sequence and analyzed the MRFs expressional patterns using quantitative real-time polymerase chain ...
Source: Gene Expression Patterns - November 4, 2015 Category: Genetics & Stem Cells Source Type: research
Spatial and temporal distribution of Patched-related protein in the Drosophila embryo
Publication date: Available online 23 October 2015 Source:Gene Expression Patterns Author(s): Carmen Bolatto, Cristina Parada, Fiorella Revello, Alejandro Zuñiga, Pablo Cabrera, Verónica Cambiazo Patched-related (Ptr) encodes a protein with 12 potential transmembrane domains and a sterol-sensing domain that is closely related in predicted topology and domain organization to Patched, the canonical receptor of the Hedgehog pathway. Here we describe the production of an antibody specific for Drosophila Ptr and analyze its spatial and temporal distribution in the embryo. We find that at early developmental s...
Source: Gene Expression Patterns - October 24, 2015 Category: Genetics & Stem Cells Source Type: research
Neuregulin1 and ErbB expression in the uninjured and regenerating olfactory mucosa
Publication date: Available online 19 October 2015 Source:Gene Expression Patterns Author(s): M.A. Gilbert, B. Lin, J. Peterson, W. Jang, J.E. Schwob Neuregulin1, a protein involved in signaling through the ErbB receptors, is required for the proper development of multiple organ systems. A complete understanding of the expression profile of Neuregulin1 is complicated by the presence of multiple isoform variants that result from extensive alternative splicing. Remarkably, these numerous protein products display a wide range of divergent functional roles, making the characterization of tissue-specific isoforms ...
Source: Gene Expression Patterns - October 20, 2015 Category: Genetics & Stem Cells Source Type: research
