Expression of MYOSIN VIIA in developing mouse cochleovestibular ganglion neurons
Publication date: Available online 7 January 2020Source: Gene Expression PatternsAuthor(s): Sarah Law, Molly Stout, Amanda Rensch, Jennifer M. RowsellAbstractMyosins make up a large super family of motor proteins responsible for actin-based motility in most eukaryotic cells. Myosin VIIA is essential for the development and function of sensory hair cells in the inner ear. The role of Myosin VIIA in the development of cochleovestibular ganglion (CVG) neurons in the mouse is largely unknown. Neurons of the CVG innervate sensory hair cells of the cochlea and vestibular organs to transmit hearing and balance information respect...
Source: Gene Expression Patterns - January 8, 2020 Category: Genetics & Stem Cells Source Type: research
A new member of the forkhead box protein family in zebrafish: Domain composition, phylogenetic implication and embryonic expression pattern
In this study, we reported a novel member of Forkhead box (Fox) proteins found in model zebrafish (Danio rerio). This new gene we cloned was primarily assigned as zgc:162612, which locates on Chromosome 3 at 26,108,033–26,109,322 in the zebrafish genome, but encodes an uncharacterized protein, LOC100037333. After we determined the nucleotide and deduced amino acid sequences of zgc:162612, we found that zgc:162612 is an intronless gene and contains 1290 base pairs encoding 308 amino acid residues. Zgc:162612 protein is composed of a highly conserved DNA-binding domain similar to that of the Fox protein family, but with ...
Source: Gene Expression Patterns - January 8, 2020 Category: Genetics & Stem Cells Source Type: research
Dynamic Delta-like1 expression in presomitic mesoderm cells during somite segmentation
Publication date: Available online 31 December 2019Source: Gene Expression PatternsAuthor(s): Akari Takagi, Akihiro Isomura, Kumiko Yoshioka-Kobayashi, Ryoichiro KageyamaAbstractDuring somite segmentation, the expression of clock genes such as Hes7 oscillates synchronously in the presomitic mesoderm (PSM). This synchronous oscillation slows down in the anterior PSM, leading to wave-like propagating patterns from the posterior to anterior PSM. Such dynamic expression depends on Notch signaling and is critical for somite formation. However, it remains to be determined how slowing oscillations in the anterior PSM are controll...
Source: Gene Expression Patterns - January 1, 2020 Category: Genetics & Stem Cells Source Type: research
Differential gene and protein expression in gastrocnemius and tibialis anterior muscle following tibial and peroneal nerve injury in rats
Publication date: Available online 4 December 2019Source: Gene Expression PatternsAuthor(s): Yaofa Lin, Zheng Xie, Jun Zhou, Gang Yin, Haodong LinAbstractPeripheral nerve injury is encountered quite commonly in the clinic, and treatment results are often not satisfactory. Therefore, promoting nerve regeneration and functional recovery is a primary goal of neuroscience research. Recovery of corresponding target muscle can differ following peripheral nerve injury, but the reasons are unknown. Herein, we investigated differential gene and protein expression in gastrocnemius and tibialis anterior muscle following tibial and co...
Source: Gene Expression Patterns - December 5, 2019 Category: Genetics & Stem Cells Source Type: research
Differential expression of foxo genes during embryonic development and in adult tissues of Xenopus tropicalis
Publication date: Available online 23 November 2019Source: Gene Expression PatternsAuthor(s): Li Zheng, Cheng-Zhou Mao, Yun-Qian Bi, Yi-Min Zhou, Zhou Zhang, Hui Zhao, Kyu-Sang Park, Ruijin Huang, Dong-Qing Cai, Xu-Feng QiAbstractThe forkhead-box transcription factors of O subfamily (FOXO) play important roles in regulation of various biological functions. We cloned foxo1, foxo3, foxo4, and foxo6 from Xenopus tropicalis (hereafter X. tropicalis), and examined their expression in embryos and adult tissues. Maternal transcripts of foxo1 and foxo3 genes are detected within the animal half of the early embryo, their zygotic tr...
Source: Gene Expression Patterns - November 24, 2019 Category: Genetics & Stem Cells Source Type: research
Editorial Board
Publication date: December 2019Source: Gene Expression Patterns, Volume 34Author(s): (Source: Gene Expression Patterns)
Source: Gene Expression Patterns - November 22, 2019 Category: Genetics & Stem Cells Source Type: research
Expression patterns of three JAK–STAT pathway genes in feather follicle development during chicken embryogenesis
Publication date: Available online 20 November 2019Source: Gene Expression PatternsAuthor(s): Yingfeng Tao, Xiaoliu Zhou, Zhiwei Liu, Xiaokang Zhang, Yangfan Nie, Xinting Zheng, Shaomei Li, Xuewen Hu, Ge Yang, Qianqian Zhao, Chunyan MouAbstractThe Janus kinase (JAK)–signal transducer and activator of transcription (STAT) (JAK–STAT) pathway is shown to restrain the hair follicles in catagen and telogen and prevent anagen reentry in murine hair follicle cycling. The early roles of JAK-STAT pathway genes in skin development remain uncharacterized in mouse and chicken models. Here, we revealed the expression patterns of th...
Source: Gene Expression Patterns - November 22, 2019 Category: Genetics & Stem Cells Source Type: research
Sox9 in mouse urogenital sinus epithelium mediates elongation of prostatic buds and expression of genes involved in epithelial cell migration
Publication date: Available online 25 October 2019Source: Gene Expression PatternsAuthor(s): Andrew J. Schneider, Joseph Gawdzik, Chad M. Vezina, Tracie R. Baker, Richard E. PetersonAbstractPrevious studies identified Sox9 as a critical mediator of prostate development but the precise stage when Sox9 acts had not been determined. A genetic approach was used to delete Sox9 from mouse urogenital sinus epithelium (UGE) prior to prostate specification. All prostatic bud types (anterior, dorsolateral and ventral) were stunted in Sox9 conditional knockouts (cKOs) even though the number of prostatic buds did not differ from that ...
Source: Gene Expression Patterns - October 26, 2019 Category: Genetics & Stem Cells Source Type: research
Expression of nucleosome assembly protein 1 like genes in zebrafish embryos
In this study, we finished the complete expression patterns of nap1l1 and nap1l4a in zebrafish embryos by whole-mount in situ hybridization. We observed maternal existence of nap1l1 transcript and that its zygotic expression is abundant and not spatially restricted at 6 somite stage, while nap1l4a mRNA is not detectable until 6 somite stage when it is weakly transcribed throughout the embryo. At 24 h post-fertilization (hpf), nap1l1 is predominantly expressed in the central nervous system, neural tube, ventral mesoderm, branchial arches, and pectoral fins, while nap1l4a mRNA is throughout the embryo, enriched in the eyes...
Source: Gene Expression Patterns - October 25, 2019 Category: Genetics & Stem Cells Source Type: research
Armadillo-like helical domain containing-4 is dynamically expressed in both the first and second heart fields
Publication date: Available online 24 October 2019Source: Gene Expression PatternsAuthor(s): Simon J. Conway, Reagan McConnell, Olga Simmons, Paige L. SniderAbstractArmadillo repeat and Armadillo-like helical domain containing proteins form a large family with diverse and fundamental functions in many eukaryotes. Herein we investigated the spatiotemporal expression pattern of Armadillo-like helical domain containing 4 (or Armh4) as an uncharacterized protein coding mouse gene, within the mouse embryo during the initial stages of heart morphogenesis. We found Armh4 is initially expressed in both first heart field as well as...
Source: Gene Expression Patterns - October 24, 2019 Category: Genetics & Stem Cells Source Type: research
The expression of FoxG1 in the early development of the European river lamprey Lampetra fluviatilis demonstrates significant heterochrony with that in other vertebrates
Publication date: December 2019Source: Gene Expression Patterns, Volume 34Author(s): Galina V. Ermakova, Alexandr V. Kucheryavyy, Andrey G. Zaraisky, Andrey V. BayramovAbstractFoxG1, a member of the Fox/Forkhead family of winged helix transcription factors, plays key roles in the induction and spatial compartmentalization of the telencephalon in vertebrates. Loss- and gain-of-function experiments have established FoxG1 as a maintenance factor for neural progenitors and a crucial player in the specification of the ventral telencephalon (subpallium). For the first time in evolution, the telencephalon appeared in the ancestor...
Source: Gene Expression Patterns - October 5, 2019 Category: Genetics & Stem Cells Source Type: research
The expression of FoxG in the early development of the European river lamprey Lampetra fluviatilis demonstrates significant heterochrony with that in other vertebrates
Publication date: Available online 28 September 2019Source: Gene Expression PatternsAuthor(s): Galina V. Ermakova, Alexandr V. Kucheryavyy, Andrey G. Zaraisky, Andrey V. BayramovAbstractFoxG1, a member of the Fox/Forkhead family of winged helix transcription factors, plays key roles in the induction and spatial compartmentalization of the telencephalon in vertebrates. Loss- and gain-of-function experiments have established FoxG1 as a maintenance factor for neural progenitors and a crucial player in the specification of the ventral telencephalon (subpallium). For the first time in evolution, the telencephalon appeared in th...
Source: Gene Expression Patterns - September 29, 2019 Category: Genetics & Stem Cells Source Type: research
Novel cis-regulatory regions in ecdysone responsive genes are sufficient to promote gene expression in Drosophila ovarian cells
Publication date: Available online 26 September 2019Source: Gene Expression PatternsAuthor(s): Samantha I. McDonald, Allison N. Beachum, Taylor D. Hinnant, Amelia J. Blake, Tierra Bynum, E. Parris Hickman, Joseph Barnes, Kaely L. Churchill, Tamesia S. Roberts, Denise E. Zangwill, Elizabeth T. AblesAbstractThe insect steroid hormone ecdysone is a key regulator of oogenesis in Drosophila melanogaster and many other species. Despite the diversity of cellular functions of ecdysone in oogenesis, the molecular regulation of most ecdysone-responsive genes in ovarian cells remains largely unexplored. We performed a functional scre...
Source: Gene Expression Patterns - September 27, 2019 Category: Genetics & Stem Cells Source Type: research
Selection and validation of castor bean (Ricinus communis) reference genes for quantitative PCR (RT-qPCR) in developing and germinating seeds and expression pattern of four ricin-family genes
This study aims to expand the set of internal control genes used for RT-qPCR experiments with Castor bean (Ricinus communis) seeds by evaluating candidate genes across several seed tissues and developmental stages. Nine reference genes were selected, including actin-11 (ACT11), tubulin alpha-2 (Tα2), elongation factor 1-alpha (EF1-α), protein phosphatase 2A-2 (PP2A2), polyubiquitin-3 (PUB3) and glyceraldehyde-3-phosphate dehydrogenase (GAPDH). Biological samples consisted of R. communis seeds in 15 stages of maturation and germination. We demonstrate that PP2A2, PUB3 and EF1-α are the most stably expressed genes across ...
Source: Gene Expression Patterns - September 17, 2019 Category: Genetics & Stem Cells Source Type: research
Ontogeny and tissue-specific expression of immune-relevant genes in Catla catla (Hamilton)
Publication date: Available online 14 September 2019Source: Gene Expression PatternsAuthor(s): P. Arya, P.K. Pradhan, Anutosh Paria, R. Sharma, Dev K. Verma, Ravindra, G. Rathore, N. SoodAbstractIndia is the second largest fish producing country in the world with production of 12.6 million tonnes (mt) in 2017–18, and Indian major carps (IMCs) share bulk of this fish production. Catla, Catla catla is the fastest growing species among IMCs. However, the survival rate of catla during larval rearing is normally lower than the other IMCs i.e rohu Labeo rohita, and mrigal Cirrhinus mrigala. Continuous efforts are devoted for t...
Source: Gene Expression Patterns - September 14, 2019 Category: Genetics & Stem Cells Source Type: research
