Expression of RNA-binding protein Rbfox1l demarcates a restricted population of dorsal telencephalic neurons within the adult zebrafish brain
In this study, we characterize Rbfox1l and Rbfox2 expression in the adult zebrafish brain. While Rbfox2 is expressed broadly, Rbfox1l is expressed in restricted populations of neurons in the dorsal telencephalon and cerebellum. In the dorsal telencephalon, Rbfox1l is expressed in a specific population of neurons spanning Dm and Dc regions. In the cerebellum, Rbfox1l and Rbfox2 are expressed in the Purkinje cell layer, reminiscent of Rbfox1 and Rbfox2 expression in the mammalian cerebellum. Our findings motivate future studies of Rbfox function in the zebrafish brain. (Source: Gene Expression Patterns)
Source: Gene Expression Patterns - January 9, 2019 Category: Genetics & Stem Cells Source Type: research
Expression of teneurin-m/odd Oz during segmentation in the beetle Tribolium castaneum
Publication date: Available online 7 January 2019Source: Gene Expression PatternsAuthor(s): Sil Jin, Jiyun O, Frank Stellabotte, Susan J. Brown, Chong Pyo ChoeAbstractThe pair-rule gene teneurin-m/odd Oz (ten-m/odz) is required for the patterning of alternate segment boundaries in the early Drosophila embryo. Mutant phenotypes of ten-m/odz display a typical pair-rule phenotype in which odd-numbered segments are eliminated. Consistent with its pair-rule function, Ten-m/Odz protein is expressed in a seven-stripe pattern before the onset of gastrulation. While expression of ten-m/odz orthologs have been characterized in sever...
Source: Gene Expression Patterns - January 8, 2019 Category: Genetics & Stem Cells Source Type: research
Expressional and functional analyses of epididymal SPINKs in mice
Publication date: Available online 25 December 2018Source: Gene Expression PatternsAuthor(s): Juri Jeong, Boyeon Lee, Jihye Kim, Jaehwan Kim, Seong Hyeon Hong, Donghyun Kim, Seungho Choi, Byung-Nam Cho, Chunghee ChoAbstractEpididymal maturation is critical for acquisition of motility and fertilizing capacity by sperm. During epididymal transit, the surface of sperm undergoes prominent sequential changes through interactions with secreted proteins, including protease inhibitors. In the present study, we characterized three epididymis-specific SPINKs (serine protease inhibitors, Kazal-type): SPINK8, SPINK11, and SPINK12. We ...
Source: Gene Expression Patterns - December 25, 2018 Category: Genetics & Stem Cells Source Type: research
Editorial Board
Publication date: December 2018Source: Gene Expression Patterns, Volume 30Author(s): (Source: Gene Expression Patterns)
Source: Gene Expression Patterns - November 29, 2018 Category: Genetics & Stem Cells Source Type: research
Developmental expression patterns of protein kinase A catalytic subunits in zebrafish
Publication date: Available online 20 November 2018Source: Gene Expression PatternsAuthor(s): Sarah E. Emerson, Benjamin K. Grebber, Morgan McNelllis, Ambrose R. Orr, Paula B. Deming, Alicia M. EbertAbstractProtein kinase A (PKA), also known as cAMP dependent protein kinase, is an essential component of many signaling pathways, many of which regulate key developmental processes. Inactive PKA is a tetrameric holoenzyme, comprised of two catalytic (PRKAC), and two regulatory subunits. Upon cAMP binding, the catalytic subunits are released and thereby activated. There are multiple isoforms of PKA catalytic subunits, but their...
Source: Gene Expression Patterns - November 21, 2018 Category: Genetics & Stem Cells Source Type: research
A tissue-specific enhancer of the C. elegans nhr-67/tailless gene drives coordinated expression in uterine stem cells and the differentiated anchor cell
Publication date: Available online 4 November 2018Source: Gene Expression PatternsAuthor(s): Shari Bodofsky, Katarina Liberatore, Lauren Pioppo, Dominic Lapadula, Lily Thompson, Susanna Birnbaum, George McClung, Akshara Kartik, Sheila Clever, Bruce WightmanAbstractThe nhr-67 nuclear receptor gene of Caenorhabditis elegans encodes the ortholog of the Drosophila tailless and vertebrate Tlx genes. In C. elegans, nhr-67 plays multiple roles in the development of the uterus during L2 and L3 larval stages. Four pre-VU cells are born in the L2 stage and form the precursor complement for the ventral surface of the mature uterus. O...
Source: Gene Expression Patterns - November 6, 2018 Category: Genetics & Stem Cells Source Type: research
Analysis of Brassica napus dehydrins and their Co-Expression regulatory networks in relation to cold stress
Publication date: Available online 6 November 2018Source: Gene Expression PatternsAuthor(s): Khazar Edrisi Maryan, Habibollah Samizadeh Lahiji, Naser Farrokhi, Hassan Hasani KomelehAbstractDehydrins (DHNs) are plant specific cold and drought stress-responsive proteins that belong to late embryogenesis abundant (LEA) protein families. B. napus DHNs (BnDHNs) were computationally analyzed to establish gene regulatory- and protein-protein interaction networks. Promoter analyses suggested functionality of phytohormones in BnDHNs gene network. The relative expressions of some BnDHNs were analyzed using qRT-PCR in seedling leaves...
Source: Gene Expression Patterns - November 6, 2018 Category: Genetics & Stem Cells Source Type: research
Expression of trpv channels during Xenopus laevis embryogenesis
Publication date: Available online 13 October 2018Source: Gene Expression PatternsAuthor(s): Chen Dong, Sudip Paudel, Nana Y. Amoh, Margaret S. SahaAbstractTransient receptor potential (TRP) cation channel genes code for an extensive family of conserved proteins responsible for a variety of physiological processes, including sensory perception, ion homeostasis, and chemical signal transduction. The TRP superfamily consists of seven subgroups, one of which is the transient receptor potential vanilloid (trpv) channel family. While trpv channels are relatively well studied in adult vertebrate organisms given their role in fun...
Source: Gene Expression Patterns - October 15, 2018 Category: Genetics & Stem Cells Source Type: research
Class I histone deacetylases in retinal progenitors and differentiating ganglion cells
ConclusionThese results indicate there may be a role for one or more of the Class I HDACs in retinal cell type-specific differentiation. (Source: Gene Expression Patterns)
Source: Gene Expression Patterns - September 2, 2018 Category: Genetics & Stem Cells Source Type: research
ALS-associated genes display CNS expression in the developing zebrafish
Publication date: Available online 27 August 2018Source: Gene Expression PatternsAuthor(s): Lauren A. Laboissonniere, Courtney L. Smith, Jacquelyn Mesenbrink, Rebecca Chowdhury, Abbie Burney, Margaret Lang, Matthew Sierra, Amy Stark, Gabriel Maldonado-Casalduc, Madison Muller, Jeffrey M. TrimarchiAbstractAmyotrophic lateral sclerosis (ALS) is characterized by progressive muscle atrophy resulting from the deterioration of motor neurons in the central nervous system (CNS). Recent genome-wide association studies have revealed several genes linked to ALS, further demonstrating the complexity of the disease. The zebrafish (Dani...
Source: Gene Expression Patterns - August 28, 2018 Category: Genetics & Stem Cells Source Type: research
Developmental expression of the slurp-like1/ly2.3/ly97.3 and slurp-like2/ly2.2/ly97.2 genes during zebrafish early embryogenesis
Publication date: Available online 24 August 2018Source: Gene Expression PatternsAuthor(s): Atsuo Kawahara, Hitoshi Morita, Kanoko Yanagi, Tomoe Ishizaka, Kiyohito Taimatsu, Rie OhgaAbstractMammalian SLURP1 and SLURP2 belong to the Ly-6/uPAR superfamily and are involved in maintaining the physiological integrity of keratinocytes. However, the developmental expression and functions of other Ly-6/uPAR family genes in vertebrates are still obscure. We have isolated novel Ly-6/uPAR family genes slurp-like1 (ly2.3/ly97.3) and slurp-like2 (ly2.2/ly97.2) in zebrafish. Both the Slurp-like1 and Slurp-like2 proteins contain the typi...
Source: Gene Expression Patterns - August 25, 2018 Category: Genetics & Stem Cells Source Type: research
Analysis of the FGFR spatiotemporal expression pattern within the chicken scleral ossicle system
Publication date: Available online 22 August 2018Source: Gene Expression PatternsAuthor(s): Shruti Kumar, Tamara A. Franz-OdendaalAbstractFibroblast Growth Factors (FGFs) play several important roles during organ morphogenesis and act as multi-functional growth factors that bind to their membrane bound receptors (FGFRs) and activate further downstream signalling pathways. Several studies have investigated the function and expression of FGF/FGFRs in endochondral bone development, however, we know little about their role in the development of neural crest derived intramembranous bones. Here, we investigate the expression of ...
Source: Gene Expression Patterns - August 23, 2018 Category: Genetics & Stem Cells Source Type: research
Expression pattern of delta-like 1 homolog in developing sympathetic neurons and chromaffin cells
In this study we have examined the precise spatiotemporal expression of DLK1 in developing sympathoadrenal cells. We show that DLK1 mRNA is highly expressed in early sympathetic neuron progenitors and that its expression depends on the presence of Phox2B. DLK1 expression becomes quickly restricted to a small subpopulation of cells in sympathetic ganglia, while virtually all chromaffin cells in the adrenal medulla and the Organ of Zuckerkandl still express high levels of DLK1 at late gestational stages. (Source: Gene Expression Patterns)
Source: Gene Expression Patterns - August 23, 2018 Category: Genetics & Stem Cells Source Type: research
Editorial Board
Publication date: September 2018Source: Gene Expression Patterns, Volume 29Author(s): (Source: Gene Expression Patterns)
Source: Gene Expression Patterns - August 19, 2018 Category: Genetics & Stem Cells Source Type: research
Spatiotemporal expression of the cocaine- and amphetamine-regulated transcript-like (cart-like) gene during zebrafish embryogenesis
Publication date: Available online 17 August 2018Source: Gene Expression PatternsAuthor(s): Atsuo Kawahara, Hitoshi Morita, Kanoko Yanagi, Hiroaki Suzuki, Takaaki Mori, Rie Ohga, Kiyohito TaimatsuAbstractThe cocaine- and amphetamine-regulated transcript (CART) genes are involved in the neural regulation of energy homeostasis; however, their developmental expressions and functions are not fully understood in vertebrates. We have identified a novel zebrafish cart-like gene that encodes a protein of 105 amino acids possessing sequence similarity to zebrafish and mammalian CART proteins. RT-PCR analysis revealed that the cart-...
Source: Gene Expression Patterns - August 18, 2018 Category: Genetics & Stem Cells Source Type: research
