Vagus nerve stimulation for genetic epilepsy with febrile seizures plus (GEFS+) accompanying seizures with impaired consciousness
We report vagus nerve stimulation (VNS) in a 6-year-old girl with GEFS+ who exhibited refractory generalized tonic-clonic seizures and complex partial seizures. (Source: Epilepsy and Behavior Case Reports)
Source: Epilepsy and Behavior Case Reports - December 29, 2016 Category: Neurology Source Type: research
Dyke –Davidoff–Masson syndrome in a Nigerian
Publication date: 2017 Source:Epilepsy & Behavior Case Reports, Volume 7 Author(s): Philip B. Adebayo, Amnat Bakare, Modupe M. Bello, Opeyemi D. Olaewe, Kolawole W. Wahab Dyke–Davidoff–Masson syndrome (DDMS) is a rare, but important cause of drug-resistant seizures. Dyke–Davidoff–Masson syndrome is a constellation of clinical features that consists of hemiparesis, seizure, facial asymmetry, and intellectual disability with distinct neuroimaging features. A 27-year-old lady presented to us with drug-resistant epilepsy, hemiparesis, and intellectual disability that necessitated her withdrawal from scho...
Source: Epilepsy and Behavior Case Reports - December 27, 2016 Category: Neurology Source Type: research
Ictal laughter and crying: Should they be classified as automatisms?
We describe a young girl with intractable focal dyscognitive seizures associated with gelastic and dacrystic features. However, neither laughter nor crying was correlated with a stereotyped electroencephalographic (EEG) pattern or involvement of a particular brain region. Additionally, based on the variety of epileptogenic foci associated with GS and DS in the literature, laughter and sobbing appear to represent ictal or peri-ictal automatisms. (Source: Epilepsy and Behavior Case Reports)
Source: Epilepsy and Behavior Case Reports - December 8, 2016 Category: Neurology Source Type: research
Functional hemispherotomy in Rasmussen syndrome in the absence of classic MRI findings
Publication date: Available online 5 December 2016 Source:Epilepsy & Behavior Case Reports Author(s): Yasunori Nagahama, Charuta Joshi, Brian Dlouhy, Angela Y. Wu, Taylor J. Abel, Gary Baumbach, Hiroto Kawasaki A 7-year-old previously healthy girl presented with a left-sided focal seizure without impaired consciousness and subsequently developed epilepsia partialis continua. Initial MRI was normal, and the subsequent images only showed a focal T2/FLAIR hyperintense area without cortical atrophy. She was diagnosed with Rasmussen syndrome by pathology and promptly treated with functional hemispherotomy. Rasm...
Source: Epilepsy and Behavior Case Reports - December 4, 2016 Category: Neurology Source Type: research
Unmasking of Myoclonus by Lacosamide in Generalized Epilepsy
We report a 67-year-old woman who experienced new-onset myoclonic seizures after initiation of lacosamide. We presume that she had an undiagnosed generalized epilepsy syndrome, likely juvenile myoclonic epilepsy. Myoclonic seizures were not reported before introducing lacosamide and completely resolved after lacosamide was discontinued. This suggests that lacosamide may have the potential to worsen myoclonus, similar to what has been reported with another sodium channel agent, lamotrigine, in some individuals with idiopathic generalized epilespy. (Source: Epilepsy and Behavior Case Reports)
Source: Epilepsy and Behavior Case Reports - November 16, 2016 Category: Neurology Source Type: research
Rapidly progressive cognitive impairment with neuropsychiatric symptoms as the initial manifestation of status epilepticus
We present two cases with sub-acute cognitive impairment and neuropsychiatric disorders (including anxiety and transient behavioral changes) as their first manifestation of NCSE. A neuropsychological profile diagnosed executive dysfunction; in addition, neurology examination revealed automatisms and 24-hour video EEG showed epileptiform activity. Although neuroimaging studies showed fronto-temporal abnormalities, neurophysiological and cognitive improvement after specific antiseizure drug treatment confirmed the diagnosis of non-convulsive status. Some theoretical considerations between mentally changes and focal epilepsy ...
Source: Epilepsy and Behavior Case Reports - November 8, 2016 Category: Neurology Source Type: research
Vagus nerve stimulation for genetic epilepsy with febrile seizures plus (GEFS+) accompanying complex partial seizures
We report vagus nerve stimulation (VNS) in a 6-year-old girl with GEFS+ who exhibited refractory generalized tonic-clonic seizures and complex partial seizures. (Source: Epilepsy and Behavior Case Reports)
Source: Epilepsy and Behavior Case Reports - November 8, 2016 Category: Neurology Source Type: research
Effect of adjunctive perampanel on the quality of sleep and daytime somnolence in patients with epilepsy
In conclusion, low-dose perampanel may improve seizure control without affecting the sleep characteristics or daytime somnolence in patients with epilepsy. (Source: Epilepsy and Behavior Case Reports)
Source: Epilepsy and Behavior Case Reports - October 29, 2016 Category: Neurology Source Type: research
Neurophysiological evidence of preserved connectivity in tuber tissue
We present a case of preserved corticospinal connectivity in a cortical tuber, in a 10year-old boy with intractable epilepsy and tuberous sclerosis complex (TSC). The patient had multiple subcortical tubers, one of which was located in the right central sulcus. In preparation for epilepsy surgery, motor mapping, by neuronavigated transcranial magnetic stimulation (nTMS) coupled with surface electromyography (EMG) was performed to locate the primary motor cortical areas. The resulting functional motor map revealed expected corticospinal connectivity in the left precentral gyrus. Surprisingly, robust contralateral deltoid an...
Source: Epilepsy and Behavior Case Reports - October 9, 2016 Category: Neurology Source Type: research
Extreme delta brush evolving into status epilepticus in a patient with Anti-NMDA encephalitis
We present a patient with anti-NMDA encephalitis who developed status epilepticus arising from the high frequency activity of the extreme delta brush. This case demonstrates that EDB is not only a marker for increased propensity for seizures, but directly implicated in seizure generation. (Source: Epilepsy and Behavior Case Reports)
Source: Epilepsy and Behavior Case Reports - September 24, 2016 Category: Neurology Source Type: research
Is there a role for diet monotherapy in adult epilepsy?
Publication date: Available online 20 September 2016 Source:Epilepsy & Behavior Case Reports Author(s): Mackenzie C. Cervenka, Bobbie J. Henry-Barron, Eric H. Kossoff Ten adults were treated with ketogenic diet monotherapy for epilepsy. Four patients were naïve to antiseizure drugs(ASD) and six previously tried and stopped ASDs. Of four treatment-naïve participants, two(50%) were free from disabling seizures on Modified Atkins Diet(MAD) monotherapy for > one year. Two(50%) stopped. Four of six patients(67%) who had previously tried ASDs became seizure-free on diet monotherapy and two experienced &...
Source: Epilepsy and Behavior Case Reports - September 20, 2016 Category: Neurology Source Type: research
A Major Miss in Prognostication after Cardiac Arrest: Burst Suppression and Brain Healing
We report a case with therapeutic hypothermia after cardiac arrest where meaningful recovery far exceeded all known outlying endpoints following cardiac arrest with loss of brainstem reflexes and subsequent status epilepticus. This man recovered after a cardiac arrest followed by a 6-week coma with absent motor response and 5weeks of burst suppression. Standard criteria suggested no chance of recovery. His recovery may relate to burst suppression to rescue neurons near neuronal cell death. Further research to understand the mechanisms of therapeutic hypothermia and late restoration of neuronal functional capacity may impro...
Source: Epilepsy and Behavior Case Reports - September 17, 2016 Category: Neurology Source Type: research
Dyke-Davidoff-Masson Syndrome in a Nigerian
Publication date: Available online 15 September 2016 Source:Epilepsy & Behavior Case Reports Author(s): Philip B. Adebayo, Amnat Bakare, Modupe M. Bello, Opeyemi D. Olaewe, Kolawole W. Wahab Dyke-Davidoff-Masson Syndrome (DDMS) is a rare but an important cause of intractable seizures. DDMS is a diagnostic constellation made up of hemiparesis, seizure, facial asymmetry and intellectual disability with distinct neuro-imaging features. A 27year old lady presented to us with refractory epilepsy, hemiparesis and intellectual disability that compelled her withdrawal from school. Her brain magnetic resonance imagin...
Source: Epilepsy and Behavior Case Reports - September 15, 2016 Category: Neurology Source Type: research
Headache maybe the initial symptom in Rasmussen's syndrome: A child case report
Conclusions This case demonstrates that the initial symptom of RS may involve only headache. (Source: Epilepsy and Behavior Case Reports)
Source: Epilepsy and Behavior Case Reports - September 14, 2016 Category: Neurology Source Type: research
Individualizing therapies with responsive epilepsy neurostimulation — A mirtazapine case study of hippocampal excitability
Conclusions Responsive neurostimulator systems in epilepsy may assess a medication's effect on hippocampal excitability. Mirtazapine worsened hippocampal excitability in a patient with bitemporal epilepsy. (Source: Epilepsy and Behavior Case Reports)
Source: Epilepsy and Behavior Case Reports - September 12, 2016 Category: Neurology Source Type: research
