Postictal neurogenic pulmonary edema: Case report and brief literature review
We present a case of a 34-year-old woman with a history of Focal epilepsy since adolescence, who presented self-limited pulmonary edema following a focal to bilateral tonic–clonic seizure with subsequent resolution of the symptoms. We also made a brief review of neurogenic pulmonary edema, its proposed pathophysiology, treatment and its relation with sudden unexpected death in epilepsy (SUDEP). (Source: Epilepsy and Behavior Case Reports)
Source: Epilepsy and Behavior Case Reports - July 10, 2018 Category: Neurology Source Type: research

Visual hallucinations: A novel complication after hemispherectomy
Publication date: 2018Source: Epilepsy & Behavior Case Reports, Volume 9Author(s): Jonas Vanags, Monisha Sachdev, Gerald Grant, Mohamad A. MikatiAbstractTwo patients at our center experienced florid visual hallucinations following hemispherectomy. The first patient had drug-resistant left hemispheric focal seizures at 20 months of age from a previous stroke. Following functional hemispherectomy at age 3, he experienced frightening hallucinations 1 month post-operatively lasting 3.5 months. Our second patient underwent subtotal hemispherectomy at age 6 for drug-resistant focal seizures from right hemispheric ...
Source: Epilepsy and Behavior Case Reports - July 10, 2018 Category: Neurology Source Type: research

Lacosamide-induced excessive laughing in a patient with Lennox–Gastaut syndrome
Publication date: 2018Source: Epilepsy & Behavior Case Reports, Volume 10Author(s): Hussein Algahtani, Bader Shirah, Raghad AlgahtaniAbstractLacosamide is one of the third-generation antiseizure drugs that block voltage-gated sodium channels by enhancing slow inactivation. The most common adverse effects of lacosamide include dizziness, headache, nausea, vomiting, diplopia, fatigue, and sedation. Less common side effects include memory impairment, weight gain, rash, and atrioventricular block. In this article, we describe a patient with Lennox–Gastaut syndrome who developed excessive laughing as a rare side effect of lac...
Source: Epilepsy and Behavior Case Reports - July 10, 2018 Category: Neurology Source Type: research

Neurosurgical treatment of nonconvulsive status epilepticus due to focal cortical dysplasia
We present a rare case of focal cortical dysplasia (FCD) and nonconvulsive status epilepticus (NCSE) treated successfully with early surgical intervention. Our case is a 9-year-old boy whose seizures, characterized by short episodes of loss of consciousness, appeared at the age of 7, and he showed progressive cognitive decline in the following years. NCSE was diagnosed, and his MRI revealed FCD in the left frontal region which was the same side as his EEG abnormality. Following lesionectomy, his NCSE disappeared and cognitive functions improved. Histopathologic analysis of the resected tissue revealed type-IIB FCD. This ca...
Source: Epilepsy and Behavior Case Reports - July 10, 2018 Category: Neurology Source Type: research

Drug-resistant epilepsy development following stem cell transplant and cyclosporine neurotoxicity induced seizures: Case report in an adult and analysis of reported cases in the literature
ConclusionsThe use of cyclosporine for GvHD prophylaxis and treatment following transplantation may cause seizures and be associated with DRE. Although discontinuation and dose decrease of CSA often reverse adverse neurological events, initial CSA-induced seizures may be associated with MTS that and subsequent greater risk of DRE development. (Source: Epilepsy and Behavior Case Reports)
Source: Epilepsy and Behavior Case Reports - July 10, 2018 Category: Neurology Source Type: research

Seizure frequency can be reduced by changing intracranial pressure: A case report in drug-resistant epilepsy
We report the case of a 23-year-old man who had undergone shunt surgery in childhood and later presented with focal impaired awareness seizures and behavior arrest. Seizures were uncontrolled despite 3 years of pharmacotherapy, but suddenly stopped after shunt removal. Our case supports the hypothesis that drug-resistant epilepsy can be influenced by changes in ICP. In particular, this case indicates that elevations in ICP may help reduce some seizures. (Source: Epilepsy and Behavior Case Reports)
Source: Epilepsy and Behavior Case Reports - July 10, 2018 Category: Neurology Source Type: research

Recurrent seizures from chronic kratom use, an atypical herbal opioid
We report a 19-year-old male with recurrent seizures that developed during daily Kratom abuse as a self-treatment for anxiety. Following recurrent focal impaired awareness seizures in addition to generalized tonic–clonic seizures, he was begun on anti-seizure drugs. Seizures subsided after completing rehabilitation. Brain MRI at 29 months revealed bilaterally symmetric T1-hyperintensity in globus pallidus, subthalamic nuclei, and cerebral peduncles. Our case suggests Kratom abuse may be associated with structural brain lesions on MRI and symptomatic focal epilepsy. (Source: Epilepsy and Behavior Case Reports)
Source: Epilepsy and Behavior Case Reports - July 10, 2018 Category: Neurology Source Type: research

Responsive neurostimulation for treatment of pediatric drug-resistant epilepsy
Publication date: 2018Source: Epilepsy & Behavior Case Reports, Volume 10Author(s): Nilika S. Singhal, Adam L. Numis, Morgan B. Lee, Edward F. Chang, Joseph E. Sullivan, Kurtis I. Auguste, Vikram R. RaoAbstractResponsive neurostimulation for epilepsy involves an implanted device that delivers direct electrical brain stimulation in response to detection of incipient seizures. Responsive neurostimulation is a safe and effective treatment for adults with drug-resistant epilepsy, but although novel treatments are critically needed for younger patients, responsive neurostimulation is currently not approved for children with dru...
Source: Epilepsy and Behavior Case Reports - July 10, 2018 Category: Neurology Source Type: research

Intracarotid amobarbital disrupts synchronous and nested oscillatory activity ipsilateral to injection
We report a patient case who underwent IAP while implanted with bilateral stereo-EEG. We analyzed the spectral power, phase amplitude coupling, and cluster-phase group synchrony during the procedure. Delta and gamma power increased bilaterally. By contrast, phase amplitude coupling increased only ipsilateral to the injection. Similarly, 4–30 Hz cluster-phase group synchrony declines and gamma cluster-phase group synchrony increases only ipsilateral to the injection. These results suggest that a possible additional mechanism for amobarbital action in the IAP is by altering the precise timing of oscillatory activity. (So...
Source: Epilepsy and Behavior Case Reports - July 10, 2018 Category: Neurology Source Type: research

Language recovery after epilepsy surgery of the Broca's area
We report transient expressive aphasia followed by recovery of speech. This case provides new insights into adult neuroplasticity of the language network. (Source: Epilepsy and Behavior Case Reports)
Source: Epilepsy and Behavior Case Reports - July 10, 2018 Category: Neurology Source Type: research

Continuous monitoring devices and seizure patterns by glucose, time and lateralized seizure onset
ConclusionSeizure onset laterality and spread varies with glucose and time of seizure (Source: Epilepsy and Behavior Case Reports)
Source: Epilepsy and Behavior Case Reports - July 10, 2018 Category: Neurology Source Type: research

Long-term use of methylphenidate in a boy with hypothalamic tumor, drug-resistant epilepsy and ADHD
Publication date: Available online 20 April 2018Source: Epilepsy & Behavior Case ReportsAuthor(s): Dobrinko Socanski, Nebojsa Jovic, Harald Beneventi, Anita Herigstad (Source: Epilepsy and Behavior Case Reports)
Source: Epilepsy and Behavior Case Reports - July 10, 2018 Category: Neurology Source Type: research

New onset syncopal events following vagus nerve stimulator implantation might be key to preventing vagus nerve stimulation-induced symptomatic bradycardia -a case report and review
ConclusionEven though arrhythmia could be critical, most cases were treated as new-onset epileptic seizures with adjustment of anti-seizure drugs for a period. To prevent cardiac asystole in VNS treatment, clinicians should be alert to the possibility of new onset syncopal events differing from habitual seizures. (Source: Epilepsy and Behavior Case Reports)
Source: Epilepsy and Behavior Case Reports - July 10, 2018 Category: Neurology Source Type: research

Drug resistant epilepsy with mesial temporal sclerosis as possible late neurological complication in two AML survivors after stem cell transplantation
Publication date: Available online 23 May 2018Source: Epilepsy & Behavior Case ReportsAuthor(s): Kwan-Ming Karen Yam, Wing-Kwan Alex Leung, Xian-Lun Zhu, Lai-Wah Eva Fung (Source: Epilepsy and Behavior Case Reports)
Source: Epilepsy and Behavior Case Reports - July 10, 2018 Category: Neurology Source Type: research

Sign and magnitude scaling properties of heart rate fluctuations following vagus nerve stimulation in a patient with drug-resistant epilepsy
This study shows that VNS therapy increases the complexity of cardiac fluctuations in a patient with drug-resistant epilepsy, reflecting an augmented HRV non-linearity and a diminished anticorrelated pattern in heart rate fluctuations. A potential clinical use of these parameters includes the early identification of bradycardia, sudden unexpected death (SUDEP) risk and preoperative VNS approaches. Thus, the scaling and magnitude properties of HRV have potential importance as a non-invasive and easy method for adequate diagnostic/prognostic in epilepsy treatment. (Source: Epilepsy and Behavior Case Reports)
Source: Epilepsy and Behavior Case Reports - July 10, 2018 Category: Neurology Source Type: research