Autosomal dominant temporal lobe epilepsy associated with heterozygous reelin mutation: 3 T brain MRI study with advanced neuroimaging methods
ConclusionsEvidence of multiple areas of functional connectivity confirm the theory of epileptogenic networks in ADTLE. Further studies are needed to elucidate this theory. (Source: Epilepsy and Behavior Case Reports)
Source: Epilepsy and Behavior Case Reports - November 2, 2018 Category: Neurology Source Type: research
Ability to knit may be impaired following right temporal lobe resection for drug-resistant epilepsy
Publication date: Available online 30 October 2018Source: Epilepsy & Behavior Case ReportsAuthor(s): Sallie Baxendale (Source: Epilepsy and Behavior Case Reports)
Source: Epilepsy and Behavior Case Reports - October 31, 2018 Category: Neurology Source Type: research
Mesial temporal Extraventricular Neurocytoma (mtEVN): A case report and literature review
ConclusionGross total resection of mtEVNs under intraoperative electrocorticography monitoring affords an excellent prognosis and successful seizure control. (Source: Epilepsy and Behavior Case Reports)
Source: Epilepsy and Behavior Case Reports - October 23, 2018 Category: Neurology Source Type: research
Epileptic spasms as the presenting seizure type in a patient with a new “O” of TORCH, congenital Zika virus infection
Publication date: Available online 18 October 2018Source: Epilepsy & Behavior Case ReportsAuthor(s): Jason Lockrow, Hannah Tully, Russell SanetoAbstractCongenital TORCH infections are a significant cause of epileptic spasms, an infantile epileptic encephalopathy, through disruptions to several pathways in neurodevelopment. Congenital Zika virus has a similar neurotropism to other TORCH agents, and leads to microcephaly, severe neurodevelopmental impairment, and high rates of early onset seizures. Here we report a child with confirmed congenital Zika virus who developed extensor epileptic spasms and hypsarrhythmia associate...
Source: Epilepsy and Behavior Case Reports - October 19, 2018 Category: Neurology Source Type: research
Sleep is associated with reduction of epileptiform discharges in benign adult familial myoclonus epilepsy
Publication date: Available online 16 October 2018Source: Epilepsy & Behavior Case ReportsAuthor(s): Takefumi Hitomi, Morito Inouchi, Katsuya Kobayashi, Shamima Sultana, Takeshi Inoue, Yuko Nakayama, Akihiro Shimotake, Masao Matsuhashi, Riki Matsumoto, Kazuo Chin, Ryosuke Takahashi, Akio IkedaAbstractTo clarify the effects of sleep on cortical irritability in benign adult familial myoclonus epilepsy (BAFME). We retrospectively compared epileptiform discharges of electroencephalographies (EEGs) between awake and sleep periods in 5 patients (mean age: 49.6 ± 20.3 years). We also analyzed polysomnography (PSG) of 1 pat...
Source: Epilepsy and Behavior Case Reports - October 17, 2018 Category: Neurology Source Type: research
Routine replacement of a vagal nerve stimulator generator leading to asystole
Publication date: Available online 11 October 2018Source: Epilepsy & Behavior Case ReportsAuthor(s): Keith Conti, Steven M. FalowskiAbstractA 52-year-old female with a longstanding history of intractable epilepsy that included complex partial seizures presented at end of service of her vagal nerve stimulator (VNS) generator. She had undergone a generator replacement in 2010 without complication; however, her latest replacement was accompanied by multiple bouts of asystole. We discuss the case, possible causes of the asystole, and its relevance to the future of VNS generator replacement and epilepsy treatment. (Source: Epil...
Source: Epilepsy and Behavior Case Reports - October 12, 2018 Category: Neurology Source Type: research
Anatomo-electro-clinical correlations of hypermotor seizures with amygdala enlargement: Hippocampal seizure origin identified using stereoelectroencephalography
Publication date: Available online 12 October 2018Source: Epilepsy & Behavior Case ReportsAuthor(s): Tomotaka Ishizaki, Satoshi Maesawa, Daisuke Nakatsubo, Hiroyuki Yamamoto, Masashi Shibata, Sachiko Kato, Mari Yoshida, Jun Natsume, Minoru Hoshiyama, Toshihiko Wakabayashi (Source: Epilepsy and Behavior Case Reports)
Source: Epilepsy and Behavior Case Reports - October 12, 2018 Category: Neurology Source Type: research
Adjunctive perampanel for glioma-associated epilepsy
Publication date: Available online 9 October 2018Source: Epilepsy & Behavior Case ReportsAuthor(s): Anastasie M. Dunn-Pirio, Sarah Woodring, Eric Lipp, James E. Herndon, Patrick Healy, Mallika Weant, Dina Randazzo, Annick Desjardins, Henry S. Friedman, Katherine B. PetersAbstractGlioma-associated epilepsy is associated with excessive glutamate signaling. We hypothesized that perampanel, an amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA)-type glutamate receptor antagonist, would treat glioma-related epilepsy. We conducted a single-arm study of adjunctive perampanel for patients with focal-onset glioma-associated s...
Source: Epilepsy and Behavior Case Reports - October 10, 2018 Category: Neurology Source Type: research
Heterotopia or overlaying cortex: What about in-between?
We describe a patient with unilateral periventricular nodular heterotopia (PNH) and drug-resistant epilepsy, whose SEEG revealed that seizures were arising from the PNH, with the almost simultaneous involvement of heterotopic neurons (“micronodules”) scattered within the white matter, and subsequently the overlying cortex. Laser ablation of heterotopic nodules and the adjacent white matter rendered the patient seizure free.This case elucidates that “micronodules” scattered in white matter between heterotopic nodules and overlying cortex might be another contributor in complex epileptogenicity of heterotopia. Detect...
Source: Epilepsy and Behavior Case Reports - October 10, 2018 Category: Neurology Source Type: research
Valproic acid as a monotherapy in methyl-CpG-binding protein 2 gene (MECP2) duplication-related epilepsy
We present the case of an eleven-year old male with MECP2 duplication. The patient presented with developmental delay and polymorphic seizure activity. The patient responded well to valproic acid (VPA) initially and upon re-challenge. This case report provides evidence for the use of VPA as an initial monotherapy for treatment of MECP2 duplication-related epilepsy. (Source: Epilepsy and Behavior Case Reports)
Source: Epilepsy and Behavior Case Reports - October 9, 2018 Category: Neurology Source Type: research
Epilepsy in patients with long QT syndrome type 1: A Norwegian family
We present a Norwegian family with mutations within the KCNQ1 gene causing cLQTS type 1 (LQT1) and epilepsy. The index patient had Jervell and Lange-Nielsen-syndrome (JLNS) with deafness and recurrent episodes of cardiac arrhythmia. The mother and the brother have Romano-Ward syndrome (RWS) with recurrent arrhythmias. Whereas the father has focal epilepsy and genetically verified LQT1, the sister has both focal epilepsy and RWS.Our findings are consistent with the notion that mutations in the KCNQ1 gene can cause epilepsy. (Source: Epilepsy and Behavior Case Reports)
Source: Epilepsy and Behavior Case Reports - October 9, 2018 Category: Neurology Source Type: research
Down syndrome associated moyamoya may worsen epilepsy control and can benefit from surgical revascularization
ConclusionIn patients with Down syndrome and moyamoya, improvements in seizure control and quality of life may occur with EC-IC bypass procedures. (Source: Epilepsy and Behavior Case Reports)
Source: Epilepsy and Behavior Case Reports - October 9, 2018 Category: Neurology Source Type: research
Recurrent focal seizures as a feature of status epilepticus presenting as a peri-ictal water drinking
We report a case of focal status epilepticus (SE) associated with peri-ictal water drinking (PIWD) behavior in a nine-year-old left-handed boy with epilepsy. We reviewed prior cases of epileptic peri-ictal water drinking. Only one adult patient with status epilepticus and PIWD has been reported previously. This is the first reported case of PIWD SE in a pediatric patient with frontal lobe epilepsy. We found PIWD to have no lateralizing value. (Source: Epilepsy and Behavior Case Reports)
Source: Epilepsy and Behavior Case Reports - October 9, 2018 Category: Neurology Source Type: research
Post-operative nonketotic hyperglycemic induced focal motor status epilepticus related to treatment with corticosteroids following standard anterior temporal lobectomy
Publication date: Available online 2 October 2018Source: Epilepsy & Behavior Case ReportsAuthor(s): Andrew Zillgitt, Abdullah Alshammaa, Muhammad Salim Kahn, Sarah Madani, Salman Zahoor, Ellen L. Air (Source: Epilepsy and Behavior Case Reports)
Source: Epilepsy and Behavior Case Reports - October 5, 2018 Category: Neurology Source Type: research
Ictal vomiting as a sign of non-convulsive status epilepticus after cerebellar hemorrhage: A case report
In conclusion, physicians must remind vomiting as a sign of status epilepticus. (Source: Epilepsy and Behavior Case Reports)
Source: Epilepsy and Behavior Case Reports - September 13, 2018 Category: Neurology Source Type: research
