Repetitive Transcranial Magnetic Stimulation Directed to a Seizure Focus Localized by High-Density EEG: A Case Report
Publication date: Available online 18 April 2018 Source:Epilepsy & Behavior Case Reports Author(s): Robert Fisher, Jing Zhou, Adam Fogarty, Aditya Joshi, Matthew Markert, Gayle K. Deutsch, Mariel Velez We demonstrate feasibility of using high-density EEG to map a neocortical seizure focus in conjunction with delivery of magnetic therapy. Our patient had refractory seizures affecting the left leg. A five-day course of placebo stimulation followed a month later by active rTMS was directed to the mapped seizure dipole. Active rTMS resulted in reduced EEG spiking, and shortening of seizure duration compared to...
Source: Epilepsy and Behavior Case Reports - April 21, 2018 Category: Neurology Source Type: research
Autoimmune Encephalitis Associated with Two Antibodies
Publication date: Available online 18 April 2018 Source:Epilepsy & Behavior Case Reports Author(s): Nikolai Gil D. Reyes, Mario B. Prado, Christian Wilson R. Turalde, Marc Laurence L. Fernandez (Source: Epilepsy and Behavior Case Reports)
Source: Epilepsy and Behavior Case Reports - April 21, 2018 Category: Neurology Source Type: research
Long-term use of methylphenidate in a boy with hypothalamic tumor, drug-resistant epilepsy and ADHD
Publication date: Available online 20 April 2018 Source:Epilepsy & Behavior Case Reports Author(s): Dobrinko Socanski, Nebojsa Jovic, Harald Beneventi, Anita Herigstad (Source: Epilepsy and Behavior Case Reports)
Source: Epilepsy and Behavior Case Reports - April 21, 2018 Category: Neurology Source Type: research
Continuous monitoring devices and seizure patterns by glucose, time and lateralized seizure onset
Conclusion Seizure onset laterality and spread varies with glucose and time of seizure (Source: Epilepsy and Behavior Case Reports)
Source: Epilepsy and Behavior Case Reports - March 23, 2018 Category: Neurology Source Type: research
Unusual Seizure Evolution: Focal-General-Focal-General
We present another unusual type characterized by focal onset with secondary generalization, that is followed immediately by continued focal activity that generalizes again without an intervening break. Better understanding of these seizure types may allow improved targeted therapies and help shed light on the mechanistic underpinnings of epilepsy. (Source: Epilepsy and Behavior Case Reports)
Source: Epilepsy and Behavior Case Reports - March 14, 2018 Category: Neurology Source Type: research
Teratoma-negative Anti-NMDA Receptor Encephalitis Presenting with a Single Generalized Tonic-clonic Seizure
Publication date: Available online 13 March 2018 Source:Epilepsy & Behavior Case Reports Author(s): Andy Cheuk-Him Ng, Miljan Tripic, Seyed M. Mirsattari Herein, we describe a case report of anti-NMDA receptor encephalitis characterized by a single generalized tonic–clonic seizure and predominantly psychiatric symptoms, persisting long after EEG abnormalities had resolved. We discuss common presentations of anti-NMDA receptor encephalitis and advocate for the inclusion of this disease entity in the differential diagnosis of patients presenting with one generalized tonic–clonic seizure and prominent psychia...
Source: Epilepsy and Behavior Case Reports - March 13, 2018 Category: Neurology Source Type: research
Seizures in HIV: The case for special consideration
Conclusion For HIV+ patients presenting with seizures/epilepsy the AED prescription and the provision of supplementary support services needs to be carefully considered. (Source: Epilepsy and Behavior Case Reports)
Source: Epilepsy and Behavior Case Reports - March 13, 2018 Category: Neurology Source Type: research
Responsive neurostimulation for treatment of pediatric drug-resistant epilepsy
Publication date: Available online 12 March 2018 Source:Epilepsy & Behavior Case Reports Author(s): Nilika S. Singhal, Adam L. Numis, Morgan B. Lee, Edward F. Chang, Joseph E. Sullivan, Kurtis I. Auguste, Vikram R. Rao Responsive neurostimulation for epilepsy involves an implanted device that delivers direct electrical brain stimulation in response to detection of incipient seizures. Responsive neurostimulation is a safe and effective treatment for adults with drug-resistant epilepsy, but, although novel treatments are critically needed for younger patients, responsive neurostimulation is currently not app...
Source: Epilepsy and Behavior Case Reports - March 12, 2018 Category: Neurology Source Type: research
Seizure Remission and Improvement of Neurological Function in Sialidosis with Perampanel Therapy
Publication date: Available online 12 March 2018 Source:Epilepsy & Behavior Case Reports Author(s): Su-Ching Hu, Kun-Long Hung, Hui-Ju Chen, Wang-Tso Lee A 15-year-old boy experienced myoclonic seizures for 3years. He initially had occasional myoclonus, gradually progressive ataxia, tremors, and psychomotor and speech regression developed. Eventually, he exhibited nearly continuous myoclonus. He received treatment of sodium valproate, levetiracetam, clobazam and phenobarbital, without efficacy. A ketogenic diet also proved ineffective. Adjunctive therapy with 4mg/day of perampanel was started and was graduall...
Source: Epilepsy and Behavior Case Reports - March 12, 2018 Category: Neurology Source Type: research
Lacosamide may improve cognition in patients with focal epilepsy: EpiTrack to compare cognitive side effects of Lacosamide and Carbamazepine
Publication date: Available online 12 March 2018 Source:Epilepsy & Behavior Case Reports Author(s): Claudio Liguori, Francesca Izzi, Natalia Manfredi, Nicola Biagio Mercuri, Fabio Placidi Carbamazepine (CBZ) is a first generation antiepileptic-drug, considered as first choice therapy in focal epilepsy but associated with cognitive side effects. Lacosamide (LCM) is a third-generation antiepileptic-drug approved for treating focal epilepsy. This case series documented the comparable efficacy of LCM and CBZ as first add on treatments in patients affected by uncontrolled focal seizures, but LCM showed the increa...
Source: Epilepsy and Behavior Case Reports - March 12, 2018 Category: Neurology Source Type: research
Drug-resistant epilepsy development following stem cell transplant and cyclosporine neurotoxicity induced seizures: Case report in an adult and analysis of reported cases in the literature
Conclusions The use of cyclosporine for GvHD prophylaxis and treatment following transplantation may cause seizures that lead to DRE. Although discontinuation and dose decrease of CSA often reverses adverse neurological events, initial CSA-induced seizures may cause irreversible damage that leads to increased risk of DRE development. (Source: Epilepsy and Behavior Case Reports)
Source: Epilepsy and Behavior Case Reports - March 10, 2018 Category: Neurology Source Type: research
Sub-lobar dysplasia — A comprehensive evaluation with neuroimaging, magnetoencephalography and histopathology
We report a right temporal sublobar dysplasia, with detailed evaluation including neuroimaging, magnetoencephalography and histopathology to further characterize the pathology. Additional pathological features included a deep collateral sulcus in the basal right temporal lobe, thinned out right corticospinal tract, and bilateral asymmetric basal ganglia changes. Magnetoencephalograpy localized the seizure focus to the posterior margin of the dysplasia. Histopathological evaluation helped exclude other types of dysplasia. Similar to a previous study, the child had Engel 1a outcome. (Source: Epilepsy and Behavior Case Reports)
Source: Epilepsy and Behavior Case Reports - February 28, 2018 Category: Neurology Source Type: research
Recurrent catamenial status epilepticus: Is it rare or an under recognized phenomenon in women with epilepsy?
Publication date: 2018 Source:Epilepsy & Behavior Case Reports, Volume 9 Author(s): Albi J. Chalissery, Emer Murphy, Gerard Mullins, Peter Widdess-Walsh, Ronan Kilbride, Norman Delanty (Source: Epilepsy and Behavior Case Reports)
Source: Epilepsy and Behavior Case Reports - February 28, 2018 Category: Neurology Source Type: research
Seizure frequency can be reduced by changing intracranial pressure: a case report of intractable epilepsy
We report the case of a 23-year-old man who had undergone shunt surgery in childhood and later presented with focal impaired awareness seizure with behavior arrest. Seizures were uncontrolled despite 3 years of pharmacotherapy, but suddenly stopped after shunt removal. Our case supports the hypothesis that intractable epilepsy can be influenced by changes in ICP. In particular, this case indicates that elevations in ICP may help reduce some seizures. (Source: Epilepsy and Behavior Case Reports)
Source: Epilepsy and Behavior Case Reports - February 11, 2018 Category: Neurology Source Type: research
Lacosamide-Induced Excessive Laughing in a Patient with Lennox –Gastaut Syndrome
Publication date: Available online 6 February 2018 Source:Epilepsy & Behavior Case Reports Author(s): Hussein Algahtani, Bader Shirah, Raghad Algahtani Lacosamide is one of the third-generation antiseizure drugs that block voltage-gated sodium channels by enhancing slow inactivation. The most common adverse effects of lacosamide include dizziness, headache, nausea, vomiting, diplopia, fatigue, and sedation. Less common side effects include memory impairment, weight gain, rash, and atrioventricular block. In this article, we describe a patient with Lennox–Gastaut syndrome who developed excessive laughing as a...
Source: Epilepsy and Behavior Case Reports - February 11, 2018 Category: Neurology Source Type: research
