Pilot data on responsive epilepsy neurostimulation, measures of sleep apnea and continuous glucose measurements
Conclusion Hippocampal nighttime responsive neurostimulation therapies did not appear to worsen measures of normal or abnormal sleep. (Source: Epilepsy and Behavior Case Reports)
Source: Epilepsy and Behavior Case Reports - January 4, 2018 Category: Neurology Source Type: research
Can the combination of hyperthermia, seizures and ion channel dysfunction cause fatal post-ictal cerebral edema in patients with SCN1A mutations?
We report on our patient and discuss whether the combination of hyperthermia and ion channel dysfunction may not only trigger seizures but also a fatal pathophysiological cascade of cerebral edema and herniation leading to cardio-respiratory collapse. (Source: Epilepsy and Behavior Case Reports)
Source: Epilepsy and Behavior Case Reports - December 24, 2017 Category: Neurology Source Type: research
Conjoint glutamic acid decarboxylase 65 and P/Q voltage gated calcium channel antibodies in autoimmune epilepsy: A case report
This report highlights a possible role of P/Q VGCC antibodies in the pathogenesis of autoimmune epilepsy. (Source: Epilepsy and Behavior Case Reports)
Source: Epilepsy and Behavior Case Reports - December 22, 2017 Category: Neurology Source Type: research
Anterior corpus callosotomy in patients with drug-resistant epilepsy: Invasive EEG findings and seizure outcomes
We examined ictal surface and intracranial electroencephalogram (iEEG) recordings in 16 patients being evaluated for anterior CC alone or in combination with focal resection, and determined the role of the iEEG in predicting postoperative seizure outcomes. In our cohort, CC improved generalized atonic seizures and focal seizures with impaired awareness but did not alter outcomes for generalized tonic-clonic or tonic seizures. Invasive EEG prior to CC did not refine the prediction of postsurgical seizure outcomes in patients with inconclusive scalp EEG. (Source: Epilepsy and Behavior Case Reports)
Source: Epilepsy and Behavior Case Reports - December 9, 2017 Category: Neurology Source Type: research
Development and Use of the Art Therapy Seizure Assessment Sculpture on an Inpatient Epilepsy Monitoring Unit
Publication date: Available online 8 December 2017 Source:Epilepsy & Behavior Case Reports Author(s): Sarah E. Brown, Tamara Shella, Elia Pestana-Knight (Source: Epilepsy and Behavior Case Reports)
Source: Epilepsy and Behavior Case Reports - December 8, 2017 Category: Neurology Source Type: research
Sub-lobar dysplasia – a comprehensive evaluation with neuroimaging, magnetoencephalography and histopathology
We report a right temporal sublobar dysplasia, with detailed evaluation with neuroimaging, magnetoencephalography and histopathology to further characterize the pathology. Additional pathological features included a deep collateral sulcus in the basal right temporal lobe, thinned out right corticospinal tract, bilateral asymmetric basal ganglia changes. Magnetoencephalograpy localized the seizure focus to the posterior margin of the dysplasia. Histopathological evaluation helped rule out other types of dysplasia. Similar to a previous study, the child had Engel 1a outcome. (Source: Epilepsy and Behavior Case Reports)
Source: Epilepsy and Behavior Case Reports - December 6, 2017 Category: Neurology Source Type: research
Evaluation of perampanel as monotherapy for focal seizures: Experience from open-label extension studies
Publication date: Available online 1 December 2017 Source:Epilepsy & Behavior Case Reports Author(s): Patrick Kwan, Scott Mintzer, Antonio Laurenza, Anna Patten, Karen Cartwright Perampanel, a selective, non-competitive α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptor antagonist, is approved for adjunctive treatment of focal seizures, with or without secondarily generalized seizures, and for primary generalized tonic–clonic seizures in patients with epilepsy aged ≥12years. Perampanel was recently approved for monotherapy use for focal seizures in the U.S.A. Anti-seizure drug monother...
Source: Epilepsy and Behavior Case Reports - December 2, 2017 Category: Neurology Source Type: research
Non ictal onset zone: A window to ictal dynamics
Publication date: 2017 Source:Epilepsy & Behavior Case Reports, Volume 8 Author(s): Pegah Afra, Sara J. Hanrahan, Spencer Sterling Kellis, Paul House The focal and network concepts of epilepsy present different aspects of electroclinical phenomenon of seizures. Here, we present a 23-year-old man undergoing surgical evaluation with left fronto-temporal electrocorticography (ECoG) and microelectrode-array (MEA) in the middle temporal gyrus (MTG). We compare action-potential (AP) and local field potentials (LFP) recorded from MEA with ECoG. Seizure onset in the mesial-temporal lobe was characterized by changes i...
Source: Epilepsy and Behavior Case Reports - November 27, 2017 Category: Neurology Source Type: research
Hemispherotomy for late post-traumatic super-refractory status epilepticus in an adult
Publication date: 2017 Source:Epilepsy & Behavior Case Reports, Volume 8 Author(s): Raghavendra Nayak, Vivek Mathew, Ramanan Rajgopal, Krishnaprabhu Raju (Source: Epilepsy and Behavior Case Reports)
Source: Epilepsy and Behavior Case Reports - November 27, 2017 Category: Neurology Source Type: research
Recurrent catamenial status epilepticus: Is it rare or an under recognised phenomenon in women with epilepsy?
Publication date: Available online 21 October 2017 Source:Epilepsy & Behavior Case Reports Author(s): Albi J. Chalissery, Emer Murphy, Gerard Mullins, Peter Widdess-Walsh, Ronan Kilbride, Norman Delanty (Source: Epilepsy and Behavior Case Reports)
Source: Epilepsy and Behavior Case Reports - November 27, 2017 Category: Neurology Source Type: research
Paroxysmal dysphasia in a 68year-old man: Enhancing the MRI spectrum!
We describe a case of a patient with glioblastoma multiforme presenting as dominant temporal lobe epilepsy. Seizures were manifest as episodes of speech arrest on a background of long-standing history of episodic speech difficulty and headache. In this case, recognizing a change in semiology allowed diagnosis of a high-grade glioma. Use of electrocorticography during surgical excision of the tumor guided safe maximal excision without damage to eloquent cortex and helped confirm the diagnosis of brain tumor-related epilepsy. (Source: Epilepsy and Behavior Case Reports)
Source: Epilepsy and Behavior Case Reports - October 14, 2017 Category: Neurology Source Type: research
An Interaction between warfarin and cannabidiol, a case report
Publication date: Available online 12 October 2017 Source:Epilepsy & Behavior Case Reports Author(s): Leslie Grayson, Brannon Vines, Kate Nichol, Jerzy P. Szaflarski (Source: Epilepsy and Behavior Case Reports)
Source: Epilepsy and Behavior Case Reports - October 13, 2017 Category: Neurology Source Type: research
Visual Hallucinations: A Novel Complication After Hemispherectomy
Publication date: Available online 2 October 2017 Source:Epilepsy & Behavior Case Reports Author(s): Jonas Vanags, Monisha Sachdev, Gerald Grant, Mohamad A. Mikati Two patients at our center experienced florid visual hallucinations following hemispherectomy. Case 1 had intractable left hemisphere focal seizures at 20months of age from a previous stroke. Following functional hemispherectomy at age 3, he experienced frightening hallucinations 1month post-operatively for 3.5months. Case 2 underwent subtotal hemispherectomy at age 6 for intractable focal seizures from right hemisphere cortical dysplasia. 18months...
Source: Epilepsy and Behavior Case Reports - October 4, 2017 Category: Neurology Source Type: research
Impairment of Consciousness Induced by Bilateral Electrical Stimulation of the Frontal Convexity
Publication date: Available online 29 September 2017 Source:Epilepsy & Behavior Case Reports Author(s): Imran H. Quraishi, Christopher F. Benjamin, Dennis D. Spencer, Hal Blumenfeld, Rafeed Alkawadri (Source: Epilepsy and Behavior Case Reports)
Source: Epilepsy and Behavior Case Reports - September 29, 2017 Category: Neurology Source Type: research
Efficacy of perampanel in a patient with epilepsia partialis continua
Publication date: Available online 27 September 2017 Source:Epilepsy & Behavior Case Reports Author(s): H. Argente-Escrig, A. Gómez-Ibáñez, V. Villanueva Perampanel is the first-in-class selective and noncompetitive α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor antagonist. It is authorized in the US and Europe as an add-on antiepileptic drug for partial-onset seizures, and for primary generalized tonic-clonic seizures. Single reports have also indicated a potential efficacy on myoclonic jerks. Here, we report a patient whose refractory epilepsia partialis continua completely resolved after ...
Source: Epilepsy and Behavior Case Reports - September 28, 2017 Category: Neurology Source Type: research
