Controllable yawning expressed as focal seizures of frontal lobe epilepsy
We present the first case of controllable yawning as a primary seizure semiology with dominant frontal lobe involvement in a 20-year-old man. Video electroencephalography recorded 8 yawning episodes accompanied with right arm movement correlating with rhythmic diffuse theta range activity with left hemispheric predominance. Magnetoencephalography coherence source imaging was consistent with persistent neuronal networks with areas of high coherence reliably present over the left lateral orbitofrontal region. Epileptogenic areas may have widespread networks involving the dominant frontal lobe in unique symptomatogenic areas....
Source: Epilepsy and Behavior Case Reports - September 11, 2016 Category: Neurology Source Type: research
A case of Symptomatic Reflex epilepsy precipitated by bathing
Publication date: Available online 3 September 2016 Source:Epilepsy & Behavior Case Reports Author(s): Sachin Sureshbabu, Dinesh Nayak, Sudhir Peter, Chindripu Sobhana, Gaurav Mittal, Vikash Aggarwal (Source: Epilepsy and Behavior Case Reports)
Source: Epilepsy and Behavior Case Reports - September 3, 2016 Category: Neurology Source Type: research
Acute Intermittent Porphyria presenting with posterior reversible encephalopathy syndrome and lateralized periodic discharges plus fast activity on cEEG
We report a 20years-old patient with 6-months history of recurrent abdominal pain, and 3-days history of vomiting, hypertension, seizures and encephalopathy. The brain MRI showed posterior reversible encephalopathy syndrome and the cEEG monitoring showed lateralized periodic discharges plus fast activity. Comprehensive CSF studies were negative. Due to severe abdominal pain without definite etiology we requested urine porphobilinogen, and serum and fecal porphyrins, which were suggestive of acute intermittent porphyria (AIP). Patient had complete resolution of her symptoms with carbohydrate loading and highly caloric diet....
Source: Epilepsy and Behavior Case Reports - August 25, 2016 Category: Neurology Source Type: research
Controllable Yawning Expressed as Focal Seizure of Frontal Lobe Epilepsy
We present the first case of controllable yawning as a primary seizure semiology with dominant frontal lobe involvement in a 20year-old-man. Video electroencephalography recorded 8 yawning episodes accompanied with right arm movement correlating with rhythmic diffuse theta range activity with left hemispheric predominance. Magnetoencephalography-Coherence Source Imaging was consistent with persistent neuronal networks with areas of high coherence reliably present over left lateral orbito-frontal region. Epileptogenic areas may have widespread networks involving the dominant frontal lobe symptomatogenic areas. (Source: Epil...
Source: Epilepsy and Behavior Case Reports - August 25, 2016 Category: Neurology Source Type: research
Fantastic confabulation in right frontal lobe epilepsy
Conclusion Fantastic confabulations are rare but may be a relatively specific behavioral marker for FLE-associated psychosis. (Source: Epilepsy and Behavior Case Reports)
Source: Epilepsy and Behavior Case Reports - August 25, 2016 Category: Neurology Source Type: research
A case report on the efficacy of vigabatrin analogue (1S, 3S)-3-amino-4-difluoromethylenyl-1-cyclopentanoic acid (CPP-115) in a patient with infantile spasms
Publication date: Available online 21 August 2016 Source:Epilepsy & Behavior Case Reports Author(s): Kyra Doumlele, Erin Conway, Julie Hedlund, Patricia Tolete, Orrin Devinsky West Syndrome is characterized by infantile spasms, a hypsarrhythmic electroencephalogram (EEG) pattern, and a poor neurodevelopmental prognosis. First-line treatments include adrenocorticotrophic hormone (ACTH) and vigabatrin, but adverse effects often limit their use. CPP-115 is a high-affinity vigabatrin analogue developed to increase therapeutic potency and to limit retinal toxicity. Here we present a child treated with CPP-115 thr...
Source: Epilepsy and Behavior Case Reports - August 20, 2016 Category: Neurology Source Type: research
‘Tickling’ seizures originating in the left frontoparietal region
We report a 10-year-old boy with mild developmental delay and epilepsy with new events of right back tickling and emotional upset. These initially appeared behavioral, causing postulation of habit behaviors or psychogenic nonepileptic seizures. Several ictal and interictal EEGs were unrevealing. Continuous EEG revealed only poorly localized frontal ictal activity. Given that his clinical symptoms suggested a parietal localization, double-density EEG electrodes were placed to better localize the epileptogenic and symptomatogenic zones. These revealed evolution of left greater than right frontoparietal discharges consistent ...
Source: Epilepsy and Behavior Case Reports - August 16, 2016 Category: Neurology Source Type: research
Praxis-induced reflex seizures mainly precipitated by writing due to a parietal focal cortical dysplasia
We report the case of a 23-year-old left-handed woman with medically intractable praxis-induced reflex seizures mainly precipitated by writing. Selective resection of subtle end-of-sulcus cortical dysplasia in the right inferior parietal lobule resulted in freedom from seizures. To the best of our knowledge, this is the first case of praxis-induced reflex seizures mainly precipitated by writing in which a focal lesion was found, and treated successfully by surgery. (Source: Epilepsy and Behavior Case Reports)
Source: Epilepsy and Behavior Case Reports - August 13, 2016 Category: Neurology Source Type: research
Atypical benign partial epilepsy of childhood with acquired neurocognitive, lexical semantic, and autistic spectrum disorder
We describe the phenotype–genotype study of a boy with ABPE with follow-up from ages 5 to 13years showing acquired oromotor and, later, a specific lexical semantic and pervasive developmental disorder. Exome sequencing identified variants in SCN9A, CPA6, and SCNM1. A direct role of the epilepsy in the pathogenesis of the oromotor and neurocognitive deficits is apparent. (Source: Epilepsy and Behavior Case Reports)
Source: Epilepsy and Behavior Case Reports - August 3, 2016 Category: Neurology Source Type: research
Wolf –Hirschhorn (4p-) syndrome with West syndrome
Publication date: 2016 Source:Epilepsy & Behavior Case Reports, Volume 6 Author(s): Hirotaka Motoi, Tohru Okanishi, Sotaro Kanai, Takuya Yokota, Tomohiro Yamazoe, Mitsuyo Nishimura, Ayataka Fujimoto, Takamichi Yamamoto, Hideo Enoki Wolf–Hirschhorn syndrome (WHS) is a chromosome disorder (4p-syndrome) which is characterized by craniofacial features and epileptic seizures. Here, we report a case of WHS with West syndrome, in whom the seizures were refractory to several antiepileptic drugs but were responsive to the addition of lamotrigine. The patient had epileptic spasms at age seven months. The interic...
Source: Epilepsy and Behavior Case Reports - August 3, 2016 Category: Neurology Source Type: research
LGI1-negative faciobrachial dystonic-like seizures originating from the insula
We report the distinct characteristics of insular faciobrachial dystonic-like seizures that would help clinicians to differentiate them from typical LGI1-positive FBDS, thus, guiding therapy while awaiting antibody results. LGI1-negative faciobrachial dystonic-like seizures should be considered when the seizure semiology includes unilateral and prolonged dystonia without loss of awareness, there is an ictal EEG correlate, MRI is suggestive of insular lesion, and when there is neither clearly associated memory impairment nor hyponatremia. (Source: Epilepsy and Behavior Case Reports)
Source: Epilepsy and Behavior Case Reports - August 3, 2016 Category: Neurology Source Type: research
Add-on perampanel in Lance –Adams syndrome
Publication date: 2016 Source:Epilepsy & Behavior Case Reports, Volume 6 Author(s): Bernhard J. Steinhoff, Matthias Bacher, Christoph Kurth, Anke M. Staack, Reinhold Kornmeier Perampanel (PER) is the first-in-class selective, noncompetitive α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptor antagonist that has been licensed and marketed as antiepileptic drug (AED) indicated for patients with partial-onset and primary generalized tonic–clonic seizures. A positive effect was reported in some patients with epileptic myoclonic jerks in idiopathic generalized epilepsy and in progressive myocl...
Source: Epilepsy and Behavior Case Reports - August 3, 2016 Category: Neurology Source Type: research
Nonconvulsive status epilepticus cases arising in connection with cephalosporins
Publication date: 2016 Source:Epilepsy & Behavior Case Reports, Volume 6 Author(s): Ibrahim Bora, Aylin Bican Demir, Pinar Uzun Cephalosporins, particularly cefepime, exert neurotoxic side effects that can lead to status epilepticus. These neurotoxic side effects include myoclonus, dystonic movements, tremor, asterixis, seizure, status epilepticus, encephalopathy, and sometimes coma. Status epilepticus, particularly nonconvulsive status epilepticus (NCSE), is a well-known but unusual complication in patients with altered renal function who were receiving treatment with intravenous cephalosporins, especially ce...
Source: Epilepsy and Behavior Case Reports - August 3, 2016 Category: Neurology Source Type: research
Status epilepticus caused by cerebral amyloid angiopathy-related inflammation
This report discusses a case of nonconvulsive status epilepticus, caused by cerebral amyloid angiopathy-related inflammation. Brain biopsy demonstrated cerebral amyloid angiopathy, with clinical and radiographic features indicative of a fluctuating inflammatory process. Immunomodulatory treatment with pulse steroids resulted in rapid and dramatic clinical and radiographic improvement. Cerebral amyloid angiopathy-related inflammation should be considered in the differential diagnosis of new-onset seizures after the age of 40, when associated with fluctuating multifocal T2 hyperintensities and petechial hemorrhages on gradie...
Source: Epilepsy and Behavior Case Reports - August 3, 2016 Category: Neurology Source Type: research
Relationship between high-frequency oscillations and spikes in a case of temporal lobe epilepsy
Conclusions These results support ripples as a marker for SOZ and show that they co-occur with spikes. Seizure onset was heralded by an increase in ripples and spikes with ripples, without an increase in spikes without ripples. We hypothesize that spikes associated with ripples may have a somewhat different pathophysiological mechanism than spikes not associated with ripples, differences that may be relevant for the timing of seizure onset. (Source: Epilepsy and Behavior Case Reports)
Source: Epilepsy and Behavior Case Reports - August 3, 2016 Category: Neurology Source Type: research
