Epidemiologic Perspectives and Innovations This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

Functional conservation of the apoptotic machinery from coral to man: the diverse and complex Bcl-2 and caspase repertoires of Acropora millepora
Conclusions: The data presented here confirm that many of the basic mechanisms involved in both the intrinsic and extrinsic apoptotic pathways were in place in the common ancestor of cnidarians and bilaterians. With the identification of most or all of the repertoires of coral Bcl-2 and caspases, our results not only provide new perspectives on the evolution of apoptotic pathways, but also a framework for future experimental studies towards a complete understanding of coral bleaching mechanisms, in which apoptotic cell death might be involved. (Source: Epidemiologic Perspectives and Innovations)
Source: Epidemiologic Perspectives and Innovations - January 16, 2016 Category: Epidemiology Authors: Aurelie MoyaKazuhiro SakamakiBenjamin MasonLotte HuismanSylvain ForêtYvonne WeissTara BullKentaro TomiiKenichiro ImaiDavid HaywardEldon BallDavid Miller Source Type: research

Situation awareness errors in anesthesia and critical care in 200 cases of a critical incident reporting system
Conclusions: SA errors are very frequent in critical incidents reported in a CIRS. The SA taxonomy was suitable to provide mechanistic insights into the central role of SA for decision-making and thus, patient safety. (Source: Epidemiologic Perspectives and Innovations)
Source: Epidemiologic Perspectives and Innovations - January 16, 2016 Category: Epidemiology Authors: Christian SchulzVeronika KrautheimAnnika HackemannMatthias KreuzerEberhard KochsKlaus Wagner Source Type: research

Deciphering transcriptional regulations coordinating the response to environmental changes
Conclusions: Lombarde provides a useful modeling scheme for deciphering the regulatory mechanisms that underlie the phenotypic responses of an organism to environmental challenges. The method can become a reliable tool for further research on genome-scale transcriptional regulation studies. (Source: Epidemiologic Perspectives and Innovations)
Source: Epidemiologic Perspectives and Innovations - January 16, 2016 Category: Epidemiology Authors: Vicente AcuñaAndrés AravenaCarito GuziolowskiDamien EveillardAnne SiegelAlejandro Maass Source Type: research

Carbon dioxide dialysis in a swine model utilizing systemic and regional anticoagulation
Background: Extracorporeal carbon dioxide removal (ECCO 2 R) has been gaining interest to potentially facilitate gas transfer and equilibrate mild to moderate hypercapnic acidosis, when standard therapy with non-invasive ventilation is deemed refractory. However, concern regarding the effectiveness of low-flow CO 2 removal remains. Additionally, the prospect to steadily reduce hypercapnia via low-flow ECCO 2 R technique is limited, especially with regional anticoagulation which potentially reduces the...
Source: Epidemiologic Perspectives and Innovations - January 16, 2016 Category: Epidemiology Authors: A. SharmaP. WeerwindO. BekersE. WoutersJ. Maessen Source Type: research

Influences on eating: a qualitative study of adolescents in a periurban area in Lima, Peru
Conclusions: To address nutrition-related issues such as obesity and iron-deficiency anemia in Peruvian adolescents, further research is warranted to elucidate the roles of certain factors shaping behavior, particularly that of family, cited numerous times as having a positive influence. Addressing nutrition-related issues such as obesity and iron-deficiency anemia in this population requires consideration of the effect of social and environmental factors in the context of adolescent lifestyles on behavior. Nutrition education messages for adolescents should consider the cultural perceptions and importance of particular fo...
Source: Epidemiologic Perspectives and Innovations - January 15, 2016 Category: Epidemiology Authors: Jinan BannaOpal BuchthalTreena DelormierHilary Creed-KanashiroMary Penny Source Type: research

The association of body image distortion with weight control behaviors, diet behaviors, physical activity, sadness, and suicidal ideation among Korean high school students: a cross-sectional study
Conclusions: Not only the over-estimation but also the under-estimation of body weight is prevalent among high school students in South Korea. Body image distortion was significantly associated with sadness and suicidal ideation. (Source: Epidemiologic Perspectives and Innovations)
Source: Epidemiologic Perspectives and Innovations - January 15, 2016 Category: Epidemiology Authors: Jounghee LeeYoungmin Lee Source Type: research

A scoping review on determinants of unmet need for family planning among women of reproductive age in low and middle income countries
Conclusion: Factors associated with unmet need for FP and non-contraception use were common across different LMIC settings. This suggests that women in LMICs face similar barriers to FP and that it is still necessary for reproductive health programs to identify FP interventions that more specifically tackle unmet need. (Source: Epidemiologic Perspectives and Innovations)
Source: Epidemiologic Perspectives and Innovations - January 15, 2016 Category: Epidemiology Authors: Joseph WulifanStephan BrennerAlbrecht JahnManuela De Allegri Source Type: research

Description of Sergentomyia phadangensis n. sp. (Diptera, Psychodidae) of Thailand
Conclusions: The description of a new species in Thailand is of importance in view of the existence of autochthonous leishmaniases. (Source: Epidemiologic Perspectives and Innovations)
Source: Epidemiologic Perspectives and Innovations - January 15, 2016 Category: Epidemiology Authors: Raxsina PolseelaJerome DepaquitChamnarn Apiwathnasorn Source Type: research

Drug poisoning deaths in the United States, 1999–2012: a statistical adjustment analysis
Conclusions: Death certificates substantially understate the involvement of opioid analgesics, sedatives, psychotropics, and drug combinations in fatal drug poisonings. Adjustment procedures that account for cases where only unspecified drugs are reported on death certificates provide more accurate information. (Source: Epidemiologic Perspectives and Innovations)
Source: Epidemiologic Perspectives and Innovations - January 15, 2016 Category: Epidemiology Authors: Christopher Ruhm Source Type: research

Perspectives and experiences of new migrants on health screening in Sweden
Conclusions: Migrants are aware of their vulnerability and the need to undergo health screening though they view it as an official requirement. Thus, those who underwent the screening were more concerned about residency rather than the actual benefits of screening. The issues highlighted in this study may limit access to and uptake of the screening service, and compromise its effectiveness. To maximize the uptake: (1) linguistically and culturally adapted information is needed, (2) other screening approaches should be tried, (3) trained medical interpreters should be used, (4) a holistic and human right approach should be ...
Source: Epidemiologic Perspectives and Innovations - January 15, 2016 Category: Epidemiology Authors: Faustine Nkulu KalengayiAnna-Karin HurtigAnnika NordstrandClas AhlmBeth Ahlberg Source Type: research

Medicaid prescription limits: policy trends and comparative impact on utilization
We examined the recent use of prescription caps by Medicaid programs and the impact of policy implementation on prescription utilization. Methods: We identified Medicaid cap policies from 2001–2010. We classified caps as applying to all prescriptions (overall caps) or only branded prescriptions (brand caps). Using state-level, aggregate prescription data, we developed interrupted time-series analyses to evaluate the impact of implementing overall caps and brand caps in a subset of states with data available before and after cap initiation. For overall caps, we examined the use of essential medications, which were classif...
Source: Epidemiologic Perspectives and Innovations - January 15, 2016 Category: Epidemiology Authors: Daniel LiebermanJennifer PolinskiNiteesh ChoudhryJerry AvornMichael Fischer Source Type: research

First-in-human study and clinical case reports of the alveolar bone regeneration with the secretome from human mesenchymal stem cells
Conclusions: MSC-CM was used safely and with less inflammatory signs and appears to have great osteogenic potential for regenerative medicine of bone. This is the first in-human clinical study of alveolar bone regeneration using MSC-CM. (Source: Epidemiologic Perspectives and Innovations)
Source: Epidemiologic Perspectives and Innovations - January 15, 2016 Category: Epidemiology Authors: Wataru KatagiriMasashi OsugiTakamasa KawaiHideharu Hibi Source Type: research

Reducing the length of postnatal hospital stay: implications for cost and quality of care
Conclusions: Many policy debates, such as that about the length of postnatal hospital-stay, demand consideration of multiple dimensions. This paper demonstrates how diverse data sources and techniques can be integrated to provide a more holistic analysis. Our study suggests that while earlier discharge from the postnatal ward may achievable, it may not generate all of the anticipated cost savings. Some useful savings may be realised but if staff and bed capacity are simply reduced in proportion to the length of stay, care quality may be compromised. (Source: Epidemiologic Perspectives and Innovations)
Source: Epidemiologic Perspectives and Innovations - January 15, 2016 Category: Epidemiology Authors: John BowersHelen Cheyne Source Type: research

Classification of fibroglandular tissue distribution in the breast based on radiotherapy planning CT
Background: Accurate segmentation of breast tissues is required for a number of applications such as model based deformable registration in breast radiotherapy. The accuracy of breast tissue segmentation is affected by the spatial distribution (or pattern) of fibroglandular tissue (FT). The goal of this study was to develop and evaluate texture features, determined from planning computed tomography (CT) data, to classify the spatial distribution of FT in the breast. Methods: Planning CT data of 23 patients were evaluated in this study. Texture features were derived from the radial glandular fraction (RGF), which described ...
Source: Epidemiologic Perspectives and Innovations - January 14, 2016 Category: Epidemiology Authors: Prabhjot JunejaPhilip EvansDavid WindridgeEmma Harris Source Type: research

Nurses’ perceptions of and satisfaction with the use of automated dispensing cabinets at the Heart and Cancer Centers in Qatar: a cross-sectional study
Conclusions: The nurses’ perceptions of and levels of satisfaction with the ADC system were very good over the 6 months after complete implementation and integration at HH and NCCCR. ADCs appear to increase efficiency in the medication process and should therefore improve the quality of care. (Source: Epidemiologic Perspectives and Innovations)
Source: Epidemiologic Perspectives and Innovations - January 14, 2016 Category: Epidemiology Authors: Manal ZaidanFatma RustomNancy KassemSumaya Al YafeiLinda PetersMohamed Ibrahim Source Type: research