Epidemiologic Perspectives and Innovations This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

Debates in allergy medicine: baked milk and egg ingestion accelerates resolution of milk and egg allergy
This article will review our current understanding of baked milk and egg tolerance and outline how these baked forms accelerates tolerance to regular milk and egg. (Source: Epidemiologic Perspectives and Innovations)
Source: Epidemiologic Perspectives and Innovations - January 26, 2016 Category: Epidemiology Authors: Stephanie Leonard Source Type: research

Aspirin inhibits epithelial-to-mesenchymal transition and migration of oncogenic K-ras-expressing non-small cell lung carcinoma cells by down-regulating E-cadherin repressor Slug
Conclusions: Cumulatively, these results signify a crucial role of the anti-inflammatory agent aspirin as a novel negative regulator of epithelial-to-mesenchymal transition thereby suggesting its candidature as a promising tool for deterring metastasis of highly invasive K-ras-expressing NSCLC cells. (Source: Epidemiologic Perspectives and Innovations)
Source: Epidemiologic Perspectives and Innovations - January 26, 2016 Category: Epidemiology Authors: Poulami KhanArgha MannaShilpi SahaSuchismita MohantyShravanti MukherjeeMinakshi MazumdarDeblina GuhaTanya Das Source Type: research

A Fluorescent Oligothiophene-Bis-Triazine ligand interacts with PrP fibrils and detects SDS-resistant oligomers in human prion diseases
Conclusions: MR100 is a powerful tool not only for studying the prion aggregation pathways regarding oligomeric and sPrP Sc species, but also for developing alternative methods for the detection of prion-infected samples. Considering our bioassay results, MR100 is a promising molecule for the development of prion decontamination approaches. (Source: Epidemiologic Perspectives and Innovations)
Source: Epidemiologic Perspectives and Innovations - January 26, 2016 Category: Epidemiology Authors: Thibaut ImberdisAdeline Ayrolles-TorroAlysson Duarte RodriguesJoan TorrentMaria Alvarez-MartinezGabor KovacsJean-Michel VerdierMike RobitzerVéronique Perrier Source Type: research

Urban traffic-derived nanoparticulate matter reduces neurite outgrowth via TNFα in vitro
Conclusions: These findings implicate microglia-derived TNFα as a mediator of nPM in air pollution-associated neurodegenerative changes which alter synaptic functions and neuronal growth. (Source: Epidemiologic Perspectives and Innovations)
Source: Epidemiologic Perspectives and Innovations - January 26, 2016 Category: Epidemiology Authors: Hank ChengDavid DavisSina HasheminassabConstantinos SioutasTodd MorganCaleb Finch Source Type: research

Chitosan nerve tube for primary repair of traumatic sensory nerve lesions of the hand without a gap: study protocol for a randomized controlled trial
This study will enroll 100 participants with traumatic sensory nerve lesions of the hand without a gap from three Trauma Care Centers. Participants will be randomized in a 1:1 ratio to primary microsurgical repair of the injured nerve with the additional use of a chitosan nerve tube or direct tension free microsurgical repair of the injured nerve alone. The static two-point discrimination of the injured finger after 6 months will be the primary outcome parameter.DiscussionIn the proposed study, the additional use of a chitosan nerve tube for a primary microsurgical repair of traumatic sensory nerve lesions of the hand wit...
Source: Epidemiologic Perspectives and Innovations - January 26, 2016 Category: Epidemiology Authors: Florian NeubrechSina HeiderLeila HarhausBerthold BickertUlrich KneserThomas Kremer Source Type: research

Gene methylation profile of gastric cancerous tissue according to tumor site in the stomach
Background: There is considerable information on the methylation of the promoter regions of different genes involved in gastric carcinogenesis. However, there is a lack of information on how this epigenetic process differs in tumors originating at different sites in the stomach.The aim of this study is to assess the methylation profiles of the MLH1, MGMT, and DAPK-1 genes in cancerous tissues from different stomach sites. Methods: Samples were acquired from 81 patients suffering stomach adenocarcinoma who underwent surgery for gastric cancer in the Lithuanian University of Health Sciences Hospital Kaunas Clinics in 2009–...
Source: Epidemiologic Perspectives and Innovations - January 26, 2016 Category: Epidemiology Authors: Rita Kupcinskaite-NoreikieneRasa UgenskieneAlius NoreikaViktoras RudzianskasJurgita GedminaiteJurgita SkiecevicieneElona Juozaityte Source Type: research

Debates in allergy medicine: baked egg and milk do not accelerate tolerance to egg and milk
There is emerging evidence that children with egg and cow’s milk allergy who can tolerate these allergens cooked in baked goods are more likely to develop tolerance. As a result a hypothesis has arisen that exposure to egg and milk in baked goods may hasten tolerance development; however, it is unclear whether children who develop tolerance do so because they have ingested low levels of egg or milk in baked products. An alternative explanation for the improved prognosis in those who can tolerate food allergens in the baked form is that tolerance to egg and milk in baked goods is simply an indicator of a phenotype that is...
Source: Epidemiologic Perspectives and Innovations - January 26, 2016 Category: Epidemiology Authors: Thanh DangRachel PetersKatrina Allen Source Type: research

Cortical activation patterns in healthy subjects during the traditional Japanese word generation task Shiritori determined by multichannel near-infrared spectroscopy
Conclusions: Cognitive functions subserved by fronto-temporal regions are elicited by Shiritori task with overt speech in healthy subjects. Thus, Shiritori might potentially be used as a clinically-relevant task to activate language-related networks in the brain. (Source: Epidemiologic Perspectives and Innovations)
Source: Epidemiologic Perspectives and Innovations - January 24, 2016 Category: Epidemiology Authors: Takayuki NakahachiRyouhei IshiiLeonides CanuetHidetoshi TakahashiMakoto IshitobiYoko KamioMasao Iwase Source Type: research

A preliminary evaluation of cytotoxicity, antihyperglycemic and antinociceptive activity of Polygonum hydropiper L. ethanolic leaf extract
In this study, we analyze the cytotoxicity property of aerial parts of the plant along with antihyperglycemic and antinociceptive activity. Methods: Cytoxicity was determined by brine shrimp lethality assay and antihyperglycemic activity was measured by oral glucose tolerance tests. Antinociceptive activity was determined by observing decreases in abdominal writhings in intraperitoneally administered acetic acid-induced pain model in mice. Results: Administration of ethanol extract of leaf led to dose-dependent and significant reductions in blood glucose levels in glucose-loaded mice. Blood sugar levels of the tested mice ...
Source: Epidemiologic Perspectives and Innovations - January 23, 2016 Category: Epidemiology Authors: Arafat OanyAl SiddikeyMohammad HossainRafiad IslamAbdullah-Al Emran Source Type: research

Meaning of self-management from the perspective of individuals with traumatic spinal cord injury, their caregivers, and acute care and rehabilitation managers: an opportunity for improved care delivery
Conclusions: Interventions that are co-created by users and health care professionals are associated with positive physical and mental health outcomes. Thus, the understanding of self-management from these varying perspectives could be applied to the development of a tailored self-management program that is relevant to individuals with traumatic SCI and their caregivers. This may involve the development of a program that uses some of the structure of traditional chronic disease self-management programs, in accordance with the beliefs held by the managers, but also incorporates elements of wellness/health promotion interven...
Source: Epidemiologic Perspectives and Innovations - January 23, 2016 Category: Epidemiology Authors: Sarah MunceFiona WebsterMichael FehlingsSharon StrausEunice JangSusan Jaglal Source Type: research

Capturing judgement strategies in risk assessments with improved quality of clinical information: How nurses’ strategies differ from the ecological model
Conclusions: Improving the quality of information by clinical simulations significantly impacted on nurses’ judgement policies of risk assessments. Nurses’ judgement strategies also varied with the increased years of experience. Such variations in processing clinical information may contribute to nurses’ suboptimal judgements in clinical practice. Constructing predictive models of common judgement situations, and increasing nurses’ awareness of information weightings in such models may help improve judgements made by nurses. (Source: Epidemiologic Perspectives and Innovations)
Source: Epidemiologic Perspectives and Innovations - January 23, 2016 Category: Epidemiology Authors: Huiqin YangCarl Thompson Source Type: research

Independent mitochondrial and nuclear exchanges arising in Rhizophagus irregularis crossed-isolates support the presence of a mitochondrial segregation mechanism
Conclusions: Our findings suggest that mitochondrial segregation might take place either during spore formation or colony development and that it might be independent of the nuclear segregation machinery. We present the basic building blocks for a better understanding of the mitochondrial inheritance process and segregation in these important symbiotic fungi. The comprehension of these processes is of great importance since it has been shown that different segregated lines of the same isolate can have variable effects on the host plant. (Source: Epidemiologic Perspectives and Innovations)
Source: Epidemiologic Perspectives and Innovations - January 23, 2016 Category: Epidemiology Authors: Laurence DauboisDenis BeaudetMohamed HijriIvan de la Providencia Source Type: research

The relationship between foot arch measurements and walking parameters in children
Conclusions: These results suggest that more than one measure of the arch may be needed elucidate the relationship between arch height and gait. (Source: Epidemiologic Perspectives and Innovations)
Source: Epidemiologic Perspectives and Innovations - January 23, 2016 Category: Epidemiology Authors: Simone GillSara KeimigDamian Kelty-StephenYa-Ching HungJeremy DeSilva Source Type: research

Evaluation of the effects of the Arm Light Exoskeleton on movement execution and muscle activities: a pilot study on healthy subjects
Conclusions: The preliminary analysis on healthy subjects supported the use of ALEx for post-stroke upper limb robotic assisted rehabilitation, and it provided clues on the effects of different rehabilitative strategies on movement and muscle coordination. (Source: Epidemiologic Perspectives and Innovations)
Source: Epidemiologic Perspectives and Innovations - January 23, 2016 Category: Epidemiology Authors: Elvira PirondiniMartina CosciaSimone MarcheschiGianluca RoasFabio SalsedoAntonio FrisoliMassimo BergamascoSilvestro Micera Source Type: research

Combination of modern plant breeding and enzyme technology to obtain highly enriched erucic acid from Crambe oil
Conclusions: The combination of modern plant breeding and enzyme technology is a promising approach for preparation of fatty acids of high purity. (Source: Epidemiologic Perspectives and Innovations)
Source: Epidemiologic Perspectives and Innovations - January 22, 2016 Category: Epidemiology Authors: Natalia VolkovaXueyuan LiLi-Hua ZhuPatrick Adlercreutz Source Type: research