Impact evaluation of a healthy lifestyle intervention to reduce cardiovascular disease risk in health centers in San José, Costa Rica and Chiapas, Mexico
Conclusion: Group education interventions at health centers have the potential to improve stage-of-change activation, and may also improve clinical outcomes. In the future, it will be essential to dedicate resources to understand ways to reach a representative group of the patient population, tailor the intervention so that patients are engaged to participate, and consider the broader family and community context that influences patients’ capacity to manage their condition. (Source: Epidemiologic Perspectives and Innovations)
Source: Epidemiologic Perspectives and Innovations - December 28, 2015 Category: Epidemiology Authors: Meredith FortSandra MurilloErika LópezAna DengoNadia Alvarado-MolinaIndira de BeaussetMaricruz CastroLiz PeñaManuel Ramírez-ZeaHomero Martínez Source Type: research

Increased prevalence and incidence of anemia among adults in transforming rural China: two cross-sectional surveys
Conclusion: Our study showed a high prevalence and incidence of anemia among adults in rural Deqing, China. Monitoring and intervention were needed urgently, especially among individuals over 45 years of age. (Source: Epidemiologic Perspectives and Innovations)
Source: Epidemiologic Perspectives and Innovations - December 28, 2015 Category: Epidemiology Authors: Xuecai WangZhaofan WuYue ChenJianfu ZhuXiaolian DongChaowei FuQingwu Jiang Source Type: research

Catatonia in Ugandan children with nodding syndrome and effects of treatment with lorazepam: a pilot study
Conclusions: About half of a selected sample of children with NS met criteria for catatonia. Catatonia scores decreased in most patients after one or two doses of lorazepam. Larger, longer, and controlled studies are warranted to assess the prevalence of catatonia in NS and to assess the use of lorazepam in NS through its effects on catatonia.Trial Registration: ClinicalTrials.gov NCT02462109Date of formal registration: June 2, 2015 (Source: Epidemiologic Perspectives and Innovations)
Source: Epidemiologic Perspectives and Innovations - December 28, 2015 Category: Epidemiology Authors: Angelina Kakooza-MwesigeDirk DhosscheRichard IdroDickens AkenaJoyce NalugyaBenard Opar Source Type: research

Social communication and emotion difficulties and second to fourth digit ratio in a large community-based sample
This study aims to investigate the association between social communication and emotion recognition difficulties and second to fourth digit ratio (2D:4D) and circulating maternal testosterone during pregnancy in a large community-based cohort: the Avon Longitudinal Study of Parents and Children (ALSPAC). A secondary aim is to investigate possible gender differences in the associations. Methods: Data on social communication (Social and Communication Disorders Checklist, N = 7165), emotion recognition (emotional triangles, N = 5844 and diagnostics analysis of non-verbal accuracy, N = 7488) and 2D:4D (second to fo...
Source: Epidemiologic Perspectives and Innovations - December 28, 2015 Category: Epidemiology Authors: Manuela BaronaRadha KothariDavid SkuseNadia Micali Source Type: research

Efficacy of TB-PCR using EBUS-TBNA samples in patients with intrathoracic granulomatous lymphadenopathy
Conclusions: TB-PCR using EBUS-TBNA samples is a useful laboratory test for diagnosing IGL. Moreover, this technique can prevent further invasive evaluation in patients whose histological and microbiological tests are non-diagnostic. (Source: Epidemiologic Perspectives and Innovations)
Source: Epidemiologic Perspectives and Innovations - December 28, 2015 Category: Epidemiology Authors: Jung EomJeong MokMin LeeKwangha LeeMin KimSun JangHae NaSeung SongGeewon LeeEun-Jung JoMi-Hyun KimKi KimHye-Kyung Park Source Type: research

Buserelin treatment to rats causes enteric neurodegeneration with moderate effects on CRF-immunoreactive neurons and Enterobacteriaceae in colon, and in acetylcholine-mediated permeability in ileum
Background: The gonadotropin-releasing hormone (GnRH) analog buserelin causes enteric neuronal loss. Acute stress or injection of corticotropin-releasing factor (CRF) affects motility, secretion, and barrier function of the gastrointestinal tract. The aim of the study was to characterize the CRF immunoreactivity in enteric neurons after buserelin treatment, and to evaluate possible effects of enteric neuropathy on gut microbiota, intestinal permeability, and stress response behavior. Results: Sixty rats were given buserelin (20 μg) or saline subcutaneously for 5 days, repeated four times with 3 weeks in-between. At the...
Source: Epidemiologic Perspectives and Innovations - December 28, 2015 Category: Epidemiology Authors: Elin SandCaroline LinningeLiudmyla LozinskaEmil EgeciogluBodil RothGöran MolinBjörn WeströmEva EkbladBodil Ohlsson Source Type: research

Evaluation performance of diagnostic methods of intestinal parasitosis in school age children in Ethiopia
Conclusion: In this study, the Kato Katz technique outperformed the other two methods but the true values for sensitivity, specificity and diagnostic values are not known. Moreover, it is labor intensive and not easily accessible. Hence, it is preferable to use FEC technique to complement the Wet mount test. (Source: Epidemiologic Perspectives and Innovations)
Source: Epidemiologic Perspectives and Innovations - December 26, 2015 Category: Epidemiology Authors: Mulat YimerTadesse HailuWondemagegn MuluBayeh Abera Source Type: research

A cancer cell-line titration series for evaluating somatic classification
Conclusions: Our cell-line titration series dataset, along with the associated verification results, was effective for this evaluation and will serve as a valuable dataset for future somatic calling algorithm development. The data is available for further analysis at the European Genome-phenome Archive under accession number EGAS00001001016. Data access requires registration through the International Cancer Genome Consortium’s Data Access Compliance Office (ICGC DACO). (Source: Epidemiologic Perspectives and Innovations)
Source: Epidemiologic Perspectives and Innovations - December 26, 2015 Category: Epidemiology Authors: Robert DenrocheLaura MullenLee TimmsTimothy BeckChristina YungLincoln SteinJohn McPhersonAndrew Brown Source Type: research

Comparative in silico analysis of SSRs in coding regions of high confidence predicted genes in Norway spruce (Picea abies) and Loblolly pine (Pinus taeda)
Background: Microsatellites or simple sequence repeats (SSRs) are DNA sequences consisting of 1–6 bp tandem repeat motifs present in the genome. SSRs are considered to be one of the most powerful tools in genetic studies. We carried out a comparative study of perfect SSR loci belonging to class I (≥20) and class II (≥12 and (Source: Epidemiologic Perspectives and Innovations)
Source: Epidemiologic Perspectives and Innovations - December 26, 2015 Category: Epidemiology Authors: Sonali RanadeYao-Cheng LinYves Van de PeerMaría García-Gil Source Type: research

Clinical significance of OCT4 and SOX2 protein expression in cervical cancer
Abstracts Background: Cancer stem cell markers have become a major research focus because of their relationship with radiation or chemotherapy resistance in cancer therapy. Cancer stem cell markers including OCT4 and SOX2 have been found in various solid tumors. Here, we investigate the expression and clinical significance of OCT4 and SOX2 in cervical cancer. Methods: To define the clinical significance of OCT4 and SOX2 expression, we performed immunohistochemistry for OCT4 and SOX2 on 305 normal cervical epithelium samples, 289 cervical intraepithelial neoplasia samples, and 161 cervical cancer cases and compared the data...
Source: Epidemiologic Perspectives and Innovations - December 26, 2015 Category: Epidemiology Authors: Bo KimHanbyoul ChoChel ChoiKris YlayaJoon-Yong ChungJae-Hoon KimStephen Hewitt Source Type: research

Safety and efficacy of VisuMax® circle patterns for flap creation and enhancement following small incision lenticule extraction
Conclusions: This initial case series demonstrates that VisuMax® Circle pattern is efficacious and a suitable method to create a corneal flap for enhancement, following small incision lenticule extraction. (Source: Epidemiologic Perspectives and Innovations)
Source: Epidemiologic Perspectives and Innovations - December 26, 2015 Category: Epidemiology Authors: Ekktet ChansueMorakot TanehsakdiSukanda SwasdibutraColm McAlinden Source Type: research

Factors associated with neonatal deaths in Chitwan district of Nepal
Conclusion: Results of this study suggest that the current community based newborn survival intervention should provide an even greater focus to essential newborn care practices, low birth weight newborns, and female education. (Source: Epidemiologic Perspectives and Innovations)
Source: Epidemiologic Perspectives and Innovations - December 26, 2015 Category: Epidemiology Authors: Rajani ShahBimala SharmaVishnu KhanalUsha PandeyAnu VishwokarmaDinesh Malla Source Type: research

Knowledge, attitudes and perceptions of stroke: a cross-sectional survey in rural and urban Uganda
Conclusion: Stroke knowledge is poor in both rural and urban Uganda. Tailored public health approaches that improve stroke awareness, knowledge and self management approaches are urgently needed to develop effective preventive measures and community response to stroke. (Source: Epidemiologic Perspectives and Innovations)
Source: Epidemiologic Perspectives and Innovations - December 26, 2015 Category: Epidemiology Authors: Mark KaddumukasaJames KayimaMartin KaddumukasaEdward DdumbaLevi MugenyiSvetlana PundikAnthony FurlanMartha SajatovicElly Katabira Source Type: research

Phytochemical investigation of crude methanol extracts of different species of Swertia from Nepal
Conclusion: Among the seven studied species, SCH showed anticipating results in total phenol content, flavonoid content and DPPH radical scavenging test. The less considered species of Swertia can be a potential source of bioactive amarogentin, and other useful therapeutic compounds in the alarming status of Swertia chirayita as shown by the phytochemical analysis. (Source: Epidemiologic Perspectives and Innovations)
Source: Epidemiologic Perspectives and Innovations - December 26, 2015 Category: Epidemiology Authors: Supreet KhanalNiroj ShakyaKrishna ThapaDeepak Pant Source Type: research

Liver cirrhosis mortality, alcohol consumption and tobacco consumption over a 62 year period in a high alcohol consumption country: a trend analysis
Conclusions: The decrease in liver cirrhosis mortality may have been caused by a decrease in alcohol drinking and tobacco smoking. Smoking may have exerted indirect effects via alcohol consumption as well as direct effects. These trends existed despite largely missing preventive efforts to reduce alcohol consumption and tobacco smoking. Increases in educational attainment in the general population may have contributed to the reductions in alcohol and tobacco consumption. Convincing evidence that the increased provision of substance use disorder treatment significantly contributed to the decrease of liver cirrhosis was not ...
Source: Epidemiologic Perspectives and Innovations - December 26, 2015 Category: Epidemiology Authors: Ulrich JohnMonika Hanke Source Type: research