Epidemiologic Perspectives and Innovations This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

Reluctance to care for patients with HIV or hepatitis B / C in Japan
Conclusions: Overall, this study suggests that anxiety arising from perceived infection risk and having a prejudicial attitude might affect the acceptance of infected patients, while personal confidence in universal precautions probably mitigates this situation. Improving nurses’ confidence in using universal precautions therefore represents a positive measure that can help reduce prejudice and improve the quality of healthcare services in Japan, as elsewhere. (Source: Epidemiologic Perspectives and Innovations)
Source: Epidemiologic Perspectives and Innovations - February 5, 2016 Category: Epidemiology Authors: Koji WadaDerek SmithTomohiro Ishimaru Source Type: research

Results of the treatment of bone metastases with modular prosthetic replacement—analysis of 67 patients
Conclusions: The use of modular prostheses is an adequate method of treatment in patients with bone metastases. A radical resection of the tumor, which prevents local recurrences and loosening of implants, gives good outcomes. Reduced joint mobility resulting from muscle attachment cutting is well tolerated and concerns mainly patients that underwent operations on the humerus. (Source: Epidemiologic Perspectives and Innovations)
Source: Epidemiologic Perspectives and Innovations - February 5, 2016 Category: Epidemiology Authors: Grzegorz Guzik Source Type: research

Journal of Experimental & Clinical Cancer Research reviewer acknowledgement 2015
Contributing reviewersThe editors of Journal of Experimental & Clinical Cancer Research would like to thank all our reviewers who have contributed their time and expertise to the journal in Volume 34 (2015). (Source: Epidemiologic Perspectives and Innovations)
Source: Epidemiologic Perspectives and Innovations - February 5, 2016 Category: Epidemiology Authors: Mauro Castelli Source Type: research

BMC Dermatology Reviewer Acknowledgement, 2015
Contributing reviewersThe editors of BMC Dermatology would like to thank all our reviewers who have contributed their time to the journal in Volume 15 (2015). (Source: Epidemiologic Perspectives and Innovations)
Source: Epidemiologic Perspectives and Innovations - February 5, 2016 Category: Epidemiology Authors: Guangde Tu Source Type: research

MiR-302a/b/c/d cooperatively sensitizes breast cancer cells to adriamycin via suppressing P-glycoprotein(P-gp) by targeting MAP/ERK kinase kinase 1 (MEKK1)
Conclusion: Our results indicate that miR-302 cooperatively sensitizes breast cancer cells to adriamycin via suppressing P-glycoprotein by targeting MEKK1 of ERK pathway. miR-302 gene cluster may be a potential target for reversing P-gp-mediated chemoresistance in breast cancer. (Source: Epidemiologic Perspectives and Innovations)
Source: Epidemiologic Perspectives and Innovations - February 3, 2016 Category: Epidemiology Authors: Lin ZhaoYan WangLongyang JiangMiao HeXuefeng BaiLifeng YuMinjie Wei Source Type: research

An observational study of the direct costs related to hospital admissions, mortality and premature death associated with liver disease in Portugal
Conclusion: In 2011, liver disease was the 10th most common cause of death and the third most important cause of premature death in Portugal. Alcohol cirrhosis was the leading cause of liver-related hospital admissions between 2001 and 2008. It appears that liver disease imposes a considerable social and economic burden on Portugal. Our results suggest that educational, legislative and therapeutic interventions to prevent morbidity, mortality and premature death from liver disease are urgently required to minimise the economic and clinical burdens.JEL Classification: I110, I140, I180, H510. (Source: Epidemiologic Perspectives and Innovations)
Source: Epidemiologic Perspectives and Innovations - February 3, 2016 Category: Epidemiology Authors: Sofia VitorRui MarinhoJosé GíriaJosé Velosa Source Type: research

Non-responders in a quitline evaluation are more likely to be smokers – a drop-out and long-term follow-up study of the Swedish National Tobacco Quitline
Conclusions: Non-responders to a 12-month follow-up smoking cessation questionnaire in a quitline setting were more likely to be smokers 1.5–3 years later. We propose a conservative correction factor of 0.8 for self-reported abstinence in telephone-based cessation studies if the response rate is approximately 55–65 %. (Source: Epidemiologic Perspectives and Innovations)
Source: Epidemiologic Perspectives and Innovations - February 3, 2016 Category: Epidemiology Authors: Eva NohlertJohn ÖhrvikÁsgeir Helgason Source Type: research

ADAMTS-18 in the host tissues exerts little effect on breast tumor progress in a murine 4T1 breast cancer model
Conclusions: We did not confirm that ADAMTS-18 in the host tissues is relevant for breast tumor progress in a murine 4 T1 breast cancer model. (Source: Epidemiologic Perspectives and Innovations)
Source: Epidemiologic Perspectives and Innovations - February 3, 2016 Category: Epidemiology Authors: Min LiuTiantian LuFang JingSuying DangWei Zhang Source Type: research

Increased fucosyl glycoconjugate by Mycoplasma hyopneumoniae enhances adherences of Pasteurella multocida type A in the ciliated epithelial cells of the respiratory tract
Conclusions: The results of the present study demonstrate that M. hyopneumoniae increases the L-fucose composition to enhance adherence of P. multocida type A to the bronchial and bronchiolar epithelial cells. (Source: Epidemiologic Perspectives and Innovations)
Source: Epidemiologic Perspectives and Innovations - February 3, 2016 Category: Epidemiology Authors: Changhoon ParkJiwoon JeongIkjae KangKyuhyung ChoiSu-Jin ParkChanhee Chae Source Type: research

Single frequency intake of α-linolenic acid rich phytosterol esters attenuates atherosclerosis risk factors in hamsters fed a high fat diet
This study aimed to explore the effects of dose and frequency of α-linolenic acid rich phytosterol esters (ALA-PE) on cholesterol and triglyceride metabolism markers focused on intestinal cholesterol absorption and bioconversion of ALA in liver. Methods: Dose-dependency study Male Syrian golden hamsters were fed high-fat diets (HFD) containing low, medium and high dose of ALA-PE (0.72 %, 2.13 % and 6.39 %) for 6 weeks. The high fat diet contained 89.5 % chow diet, 0.2 % cholesterol, 10 % lard and 0.3 % bile salt.Dose-frequency study Male Syrian golden hamsters were provided: (I) 0.4 mL/100 g peanut oil by gavage...
Source: Epidemiologic Perspectives and Innovations - February 3, 2016 Category: Epidemiology Authors: Qianchun DengXiao YuJiqu XuXiuying KouMingming ZhengFenghong HuangQingde HuangLan Wang Source Type: research

Schistosoma haematobium and soil-transmitted Helminths in Tana Delta District of Kenya: infection and morbidity patterns in primary schoolchildren from two isolated villages
Background: Schistosomes and soil-transmitted helminths (STH) (hookworm, Trichuris trichiura and Ascaris lumbricoides) are widely distributed in developing countries where they infect over 230 million and 1.5 billion people, respectively. The parasites are frequently co-endemic and many individuals are co-infected with two or more of the species, but information on how the parasites interact in co-infected individuals is scarce. The present study assessed Schistosoma haematobium and STH infection and morbidity patterns among school children in a hyper-endemic focus in the Tana River delta of coastal Kenya. Methods: Two hun...
Source: Epidemiologic Perspectives and Innovations - February 3, 2016 Category: Epidemiology Authors: Kariuki NjaanakeBirgitte VennervaldPaul SimonsenHenry MadsenDunstan MukokoGachuhi KimaniWalter JaokoBenson Estambale Source Type: research

Monitoring patient care through health facility exit interviews: an assessment of the Hawthorne effect in a trial of adherence to malaria treatment guidelines in Tanzania
Background: Survey of patients exiting health facilities is a common way to assess consultation practices. It is, however, unclear to what extent health professionals may change their practices when they are aware of such interviews taking place, possibly paying more attention to following recommended practices. This so-called Hawthorne effect could have important consequences for interpreting research and programme monitoring, but has rarely been assessed. Methods: A three-arm cluster-randomised trial of interventions to improve adherence to guidelines for the use of anti-malarial drugs was conducted in Tanzania. Patient ...
Source: Epidemiologic Perspectives and Innovations - February 3, 2016 Category: Epidemiology Authors: Baptiste LeurentHugh ReyburnFlorida MuroHilda MbakilwaDavid Schellenberg Source Type: research

ClinQC: a tool for quality control and cleaning of Sanger and NGS data in clinical research
Conclusions: ClinQC is a powerful and easy to handle pipeline for quality control and trimming in clinical research. ClinQC is written in Python with multiprocessing capability, run on all major operating systems and is available at https://sourceforge.net/projects/clinqc. (Source: Epidemiologic Perspectives and Innovations)
Source: Epidemiologic Perspectives and Innovations - February 2, 2016 Category: Epidemiology Authors: Ram PandeyStephan PabingerAlbert KriegnerAndreas Weinhäusel Source Type: research

Pulmonary metastasectomy in pediatric patients
Conclusions: Multidisciplinary treatment involving pediatric oncologists, surgeons, and radiation oncologists is necessary to obtain positive results in children who have pulmonary metastases of oncological diseases. Wedge resection is a suitable option for children because less lung tissue is resected. (Source: Epidemiologic Perspectives and Innovations)
Source: Epidemiologic Perspectives and Innovations - February 2, 2016 Category: Epidemiology Authors: Basak ErginelFeryal Gun SoysalErbug KeskinRejin KebudiAlaaddin CelikTansu Salman Source Type: research

Virucidal activity of Haemaphysalis longicornis longicin P4 peptide against tick-borne encephalitis virus surrogate Langat virus
Conclusion: Our results suggest that longicin P4 has in vitro antiviral activity against LGTV but not against a non-enveloped virus such as adenovirus. Likewise, though most cationic antimicrobial peptides like longicin act directly on target membranes, the exact mechanism of membrane targeting of longicin P4 in enveloped viruses, such as LGTV, requires further investigation. Lastly, while the in vitro virucidal capacity of longicin P4 was confirmed in this study, the role of the endogenous tick longicin in the antiviral defense of H. longicornis against LGTV still remains to be demonstrated. (Source: Epidemiologic Perspec...
Source: Epidemiologic Perspectives and Innovations - February 2, 2016 Category: Epidemiology Authors: Melbourne TalactacKentaro YoshiiHiroki MaedaKodai KusakisakoEmmanuel HernandezNaotoshi TsujiKozo FujisakiRemil GalayTetsuya TanakaMasami Mochizuki Source Type: research