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Wiley Interdisciplinary Reviews: Nanomedicine and Nanobiotechnology, Ahead of Print. (Source: Wiley Interdisciplinary Reviews: Nanomedicine and Nanobiotechnology)
Source: Wiley Interdisciplinary Reviews: Nanomedicine and Nanobiotechnology - November 23, 2017 Category: Nanotechnology Source Type: research

Extracellular matrix remodeling in 3D: implications in tissue homeostasis and disease progression
The extracellular matrix (ECM) plays a critical role in regulating cell behavior during tissue homeostasis and in disease progression. Through a combination of adhesion, contraction, alignment of ECM proteins and subsequent degradation, cells change the chemical, mechanical, and physical properties of their surrounding matrix. Other contributing factors to matrix remodeling are the de novo synthesis of ECM proteins, post‐translational modifications and receptor‐mediated internalization. In this review, we highlight how each of these processes contributes to the maintenance of homeostasis and in disease conditions such ...
Source: Wiley Interdisciplinary Reviews: Nanomedicine and Nanobiotechnology - November 23, 2017 Category: Nanotechnology Authors: Andrew J. Ford, Padmavathy Rajagopalan Tags: Overview Source Type: research

Breaking free from vascular confinement: status and prospects for submicron ultrasound contrast agents
Wiley Interdisciplinary Reviews: Nanomedicine and Nanobiotechnology, EarlyView. (Source: Wiley Interdisciplinary Reviews: Nanomedicine and Nanobiotechnology)
Source: Wiley Interdisciplinary Reviews: Nanomedicine and Nanobiotechnology - November 17, 2017 Category: Nanotechnology Authors: Carly Pellow , David E. Goertz , Gang Zheng Source Type: research

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Wiley Interdisciplinary Reviews: Nanomedicine and Nanobiotechnology, Ahead of Print. (Source: Wiley Interdisciplinary Reviews: Nanomedicine and Nanobiotechnology)
Source: Wiley Interdisciplinary Reviews: Nanomedicine and Nanobiotechnology - November 17, 2017 Category: Nanotechnology Source Type: research

Recent progress on fabrication and drug delivery applications of nanostructured hydroxyapatite
Through this brief review, we provide a comprehensive historical background of the development of nanostructured hydroxyapatite (nHAp), and its application potentials for controlled drug delivery, drug conjugation, and other biomedical treatments. Aspects associated with efficient utilization of hydroxyapatite (HAp) nanostructures such as their synthesis, interaction with drug molecules, and other concerns, which need to be resolved before they could be used as a potential drug carrier in body system, are discussed. This review focuses on the evolution of perceptions, practices, and accomplishments in providing improved de...
Source: Wiley Interdisciplinary Reviews: Nanomedicine and Nanobiotechnology - November 1, 2017 Category: Nanotechnology Authors: Sudip Mondal, Sergy V. Dorozhkin, Umapada Pal Tags: Advanced Review Source Type: research

Breaking free from vascular confinement: status and prospects for submicron ultrasound contrast agents
This article reviews the status and prospects of exogenous agents including nanobubbles, echogenic liposomes, gas vesicles, cavitation seeds, and nanodroplets, and assesses outstanding criticisms preventing their advance. For further resources related to this article, please visit the WIREs website. While microbubbles are confined to remain in the vasculature, physiological consequences of tumor microvasculature afford opportunities for nanoscale agents to escape the intravascular space and expand bubble‐mediated potential. Here we review the status and prospects of nanoscale exogenous agents as ultrasound theranostic m...
Source: Wiley Interdisciplinary Reviews: Nanomedicine and Nanobiotechnology - November 1, 2017 Category: Nanotechnology Authors: Carly Pellow, David E. Goertz, Gang Zheng Tags: Opinion Source Type: research

The protein corona on nanoparticles as viewed from a nanoparticle ‐sizing perspective
Most surfaces of engineered nanoparticles (NPs) are reactive toward biomolecules. Therefore, whenever NPs become immersed in biological fluids, proteins and other biomolecules bind to the NP surface, forming an adsorption layer (biomolecular corona) that modifies the NPs’ physicochemical properties and subsequent interactions with living systems. Its exploration is a formidable endeavor owing to the enormous diversity of engineered NPs in terms of their physicochemical properties and the vast number of biomolecules available in biofluids that may bind to NPs with widely different strengths. Significant progress has been ...
Source: Wiley Interdisciplinary Reviews: Nanomedicine and Nanobiotechnology - October 26, 2017 Category: Nanotechnology Authors: Haixia Wang, Youhui Lin, Karin Nienhaus, G. Ulrich Nienhaus Tags: Opinion Source Type: research

The protein corona on nanoparticles as viewed from a nanoparticle ‐sizing perspective
Wiley Interdisciplinary Reviews: Nanomedicine and Nanobiotechnology, EarlyView. (Source: Wiley Interdisciplinary Reviews: Nanomedicine and Nanobiotechnology)
Source: Wiley Interdisciplinary Reviews: Nanomedicine and Nanobiotechnology - October 26, 2017 Category: Nanotechnology Authors: Haixia Wang , Youhui Lin , Karin Nienhaus , G. Ulrich Nienhaus Source Type: research

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Wiley Interdisciplinary Reviews: Nanomedicine and Nanobiotechnology, Ahead of Print. (Source: Wiley Interdisciplinary Reviews: Nanomedicine and Nanobiotechnology)
Source: Wiley Interdisciplinary Reviews: Nanomedicine and Nanobiotechnology - October 26, 2017 Category: Nanotechnology Source Type: research

Drug nanocrystals for cancer therapy
Drug nanocrystals (NCs) with fascinating physicochemical properties have attracted great attention in drug delivery. High drug‐loading efficiency, great structural stability, steady dissolution, and long circulation time are a few examples of these properties, which makes drug NCs an excellent formulation for efficient cancer therapy. In the last two decades, there are a lot of hydrophobic or lipophilic drugs, such as paclitaxel (PTX), camptothecin (CPT), thymectacin, busulfan, cyclosporin A, 2‐devinyl‐2‐(1‐hexyloxyethyl) pyropheophorbide (HPPH), and so on, which have been formulated into drug NCs for cancer ther...
Source: Wiley Interdisciplinary Reviews: Nanomedicine and Nanobiotechnology - October 17, 2017 Category: Nanotechnology Authors: Xiaoqing Miao, Wuwei Yang, Tao Feng, Jing Lin, Peng Huang Tags: Advanced Review Source Type: research

Drug nanocrystals for cancer therapy
Wiley Interdisciplinary Reviews: Nanomedicine and Nanobiotechnology,Volume 10, Issue 3, May/June 2018. (Source: Wiley Interdisciplinary Reviews: Nanomedicine and Nanobiotechnology)
Source: Wiley Interdisciplinary Reviews: Nanomedicine and Nanobiotechnology - October 17, 2017 Category: Nanotechnology Authors: Xiaoqing Miao , Wuwei Yang , Tao Feng , Jing Lin , Peng Huang Source Type: research

Drug nanocrystals for cancer therapy
Wiley Interdisciplinary Reviews: Nanomedicine and Nanobiotechnology, EarlyView. (Source: Wiley Interdisciplinary Reviews: Nanomedicine and Nanobiotechnology)
Source: Wiley Interdisciplinary Reviews: Nanomedicine and Nanobiotechnology - October 17, 2017 Category: Nanotechnology Source Type: research