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Wiley Interdisciplinary Reviews: Nanomedicine and Nanobiotechnology, Ahead of Print. (Source: Wiley Interdisciplinary Reviews: Nanomedicine and Nanobiotechnology)
Source: Wiley Interdisciplinary Reviews: Nanomedicine and Nanobiotechnology - October 17, 2017 Category: Nanotechnology Source Type: research

Issue Information
(Source: Wiley Interdisciplinary Reviews: Nanomedicine and Nanobiotechnology)
Source: Wiley Interdisciplinary Reviews: Nanomedicine and Nanobiotechnology - October 12, 2017 Category: Nanotechnology Tags: Issue Information Source Type: research

Cover Image, Volume 9, Issue 6
In the Overview by Sangtani and Nag et al., the authors detail recent advances in multifunctional therapeutic nanoparticles (NPs) for drug delivery and imaging. The distinction is made between hard NPs such as quantum dots and gold NPs (where drug cargos are attached to the NP surface) and soft NPs such as liposomes and micelles (which allow both core loading and surface attachment). The image shows a cut away view of a mammalian cell interfaced with soft (foreground left) and hard (foreground right) NPs during the delivery of surface‐appended (green spheres) and core‐loaded (red rods) cargos. Illustration is courtesy ...
Source: Wiley Interdisciplinary Reviews: Nanomedicine and Nanobiotechnology - October 12, 2017 Category: Nanotechnology Authors: Ajmeeta Sangtani, Okhil K. Nag, Lauren D. Field, Joyce C. Breger, James B. Delehanty Tags: Cover Image Source Type: research

Mechanisms of carbon nanotube ‐induced pulmonary fibrosis: a physicochemical characteristic perspective
Wiley Interdisciplinary Reviews: Nanomedicine and Nanobiotechnology,Volume 10, Issue 3, May/June 2018. (Source: Wiley Interdisciplinary Reviews: Nanomedicine and Nanobiotechnology)
Source: Wiley Interdisciplinary Reviews: Nanomedicine and Nanobiotechnology - October 6, 2017 Category: Nanotechnology Authors: Katherine S. Duke , James C. Bonner Source Type: research

Mechanisms of carbon nanotube ‐induced pulmonary fibrosis: a physicochemical characteristic perspective
Wiley Interdisciplinary Reviews: Nanomedicine and Nanobiotechnology, EarlyView. (Source: Wiley Interdisciplinary Reviews: Nanomedicine and Nanobiotechnology)
Source: Wiley Interdisciplinary Reviews: Nanomedicine and Nanobiotechnology - October 6, 2017 Category: Nanotechnology Source Type: research

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Wiley Interdisciplinary Reviews: Nanomedicine and Nanobiotechnology, Ahead of Print. (Source: Wiley Interdisciplinary Reviews: Nanomedicine and Nanobiotechnology)
Source: Wiley Interdisciplinary Reviews: Nanomedicine and Nanobiotechnology - October 6, 2017 Category: Nanotechnology Source Type: research

A hindsight reflection on the clinical studies of poly(l ‐glutamic acid)‐paclitaxel
Wiley Interdisciplinary Reviews: Nanomedicine and Nanobiotechnology,Volume 10, Issue 3, May/June 2018. (Source: Wiley Interdisciplinary Reviews: Nanomedicine and Nanobiotechnology)
Source: Wiley Interdisciplinary Reviews: Nanomedicine and Nanobiotechnology - September 11, 2017 Category: Nanotechnology Authors: Jun Zhao , Eugene J. Koay , Tingting Li , Xiaoxia Wen , Chun Li Source Type: research

Two decades of dendrimers as versatile MRI agents: a tale with and without metals
Wiley Interdisciplinary Reviews: Nanomedicine and Nanobiotechnology,Volume 10, Issue 3, May/June 2018. (Source: Wiley Interdisciplinary Reviews: Nanomedicine and Nanobiotechnology)
Source: Wiley Interdisciplinary Reviews: Nanomedicine and Nanobiotechnology - September 11, 2017 Category: Nanotechnology Authors: Michael T. McMahon , Jeff W. M. Bulte Source Type: research

Two decades of dendrimers as versatile MRI agents: a tale with and without metals
Wiley Interdisciplinary Reviews: Nanomedicine and Nanobiotechnology, EarlyView. (Source: Wiley Interdisciplinary Reviews: Nanomedicine and Nanobiotechnology)
Source: Wiley Interdisciplinary Reviews: Nanomedicine and Nanobiotechnology - September 11, 2017 Category: Nanotechnology Source Type: research

A hindsight reflection on the clinical studies of poly(l ‐glutamic acid)‐paclitaxel
Wiley Interdisciplinary Reviews: Nanomedicine and Nanobiotechnology, EarlyView. (Source: Wiley Interdisciplinary Reviews: Nanomedicine and Nanobiotechnology)
Source: Wiley Interdisciplinary Reviews: Nanomedicine and Nanobiotechnology - September 11, 2017 Category: Nanotechnology Source Type: research

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Wiley Interdisciplinary Reviews: Nanomedicine and Nanobiotechnology, Ahead of Print. (Source: Wiley Interdisciplinary Reviews: Nanomedicine and Nanobiotechnology)
Source: Wiley Interdisciplinary Reviews: Nanomedicine and Nanobiotechnology - September 11, 2017 Category: Nanotechnology Source Type: research

A hindsight reflection on the clinical studies of poly(l ‐glutamic acid)‐paclitaxel
Chemotherapy for cancer treatment is limited by the excessive toxicity to normal tissues. The design of chemodrug‐loaded nanoformulations provides a unique approach to improve the treatment efficacy while minimizing toxicity. Despite the numerous publications of nanomedicine for the last several decades, however, only a small fraction of the developed nanoformulations have entered clinical trials, with even fewer being approved for clinical application. Poly(l‐glutamic acid)‐paclitaxel (PG‐TXL) belongs to the few formulations that reached phase III clinical trials. Unfortunately, the development of PG‐TXL stopped...
Source: Wiley Interdisciplinary Reviews: Nanomedicine and Nanobiotechnology - September 11, 2017 Category: Nanotechnology Authors: Jun Zhao, Eugene J. Koay, Tingting Li, Xiaoxia Wen, Chun Li Tags: Overview Source Type: research

Mechanisms of carbon nanotube ‐induced pulmonary fibrosis: a physicochemical characteristic perspective
Carbon nanotubes (CNTs) are engineered nanomaterials (ENMs) with numerous beneficial applications. However, they could pose a risk to human health from occupational or consumer exposures. Rodent models demonstrate that exposure to CNTs via inhalation, instillation, or aspiration results in pulmonary fibrosis. The severity of the fibrogenic response is determined by various physicochemical properties of the nanomaterial such as residual metal catalyst content, rigidity, length, aggregation status, or surface charge. CNTs are also increasingly functionalized post‐synthesis with organic or inorganic agents to modify or enha...
Source: Wiley Interdisciplinary Reviews: Nanomedicine and Nanobiotechnology - September 1, 2017 Category: Nanotechnology Authors: Katherine S. Duke, James C. Bonner Tags: Advanced Review Source Type: research

Two decades of dendrimers as versatile MRI agents: a tale with and without metals
Dendrimers or dendritic polymers are a class of compounds with great potential for nanomedical use. Some of their properties, including their rigidity, low polydispersity and the ease with which their surfaces can be modified make them particularly well suited for use as MRI diagnostic or theranostic agents. For the past 20 years, researchers have recognized this potential and refined dendrimer formulations to optimize these nanocarriers for a host of MRI applications, including blood pool imaging agents, lymph node imaging agents, tumor‐targeted theranostic agents and cell tracking agents. This review summarizes the var...
Source: Wiley Interdisciplinary Reviews: Nanomedicine and Nanobiotechnology - September 1, 2017 Category: Nanotechnology Authors: Michael T. McMahon, Jeff W. M. Bulte Tags: Advanced Review Source Type: research