Wiley Interdisciplinary Reviews: Nanomedicine and Nanobiotechnology This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

Challenges in carrier‐mediated intracellular delivery: moving beyond endosomal barriers
The deployment of molecular to microscale carriers for intracellular delivery has tremendous potential for biology and medicine, especially for in vivo therapies. The field remains limited, however, by a poor understanding of how carriers gain access to the cell interior. In this review, we provide an overview of the different types of carriers, their speculated modes of entry, putative pathways of vesicular transport, and sites of endosomal escape. We compare this alongside pertinent examples from the cell biology of how viruses, bacteria, and their effectors enter cells and escape endosomal confinement. We anticipate ins...
Source: Wiley Interdisciplinary Reviews: Nanomedicine and Nanobiotechnology - November 1, 2015 Category: Nanotechnology Authors: Martin P. Stewart, Anna Lorenz, James Dahlman, Gaurav Sahay Tags: Advanced Review Source Type: research

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(Source: Wiley Interdisciplinary Reviews: Nanomedicine and Nanobiotechnology)
Source: Wiley Interdisciplinary Reviews: Nanomedicine and Nanobiotechnology - October 12, 2015 Category: Nanotechnology Tags: Issue Information Source Type: research

Osteogenic growth peptide and its use as a bio‐conjugate in regenerative medicine applications
For nearly 2000 years, biomaterials have been used as damaged tissue implants. A field that started with wood and gold tissue replacements has evolved into an advanced science which combines ideas of cellular biology, engineering, and synthetic chemistry to produce bioresorbable materials capable of directing specific cell responses. With the overwhelming number of failed bone defect repairs every year, bone tissue engineering has become an important area of study. Both naturally occurring and synthetic polymeric materials have shown promising results for bone regeneration with their wide range of mechanical and degradatio...
Source: Wiley Interdisciplinary Reviews: Nanomedicine and Nanobiotechnology - September 22, 2015 Category: Nanotechnology Authors: Gina M. Policastro, Matthew L. Becker Tags: Advanced Review Source Type: research

Temporal flickering of contrast agents for enhanced optical imaging: a review
The temporal flickering of contrast agents that labels a biological sample is a unique modality for cellular imaging with single molecule sensitivity. It improves the signal‐to‐noise ratio statistics associated with the noisy in vivo environment and has promising applications in single particle tracking and super‐resolution microscopy techniques. The flickering can be triggered either statistically through the mechanism of temporal fluctuations of the emitter or through external modulation. The enriching toolbox of contrast agents that are feasible for biomedical imaging for the flickering methods will be discussed, ...
Source: Wiley Interdisciplinary Reviews: Nanomedicine and Nanobiotechnology - September 15, 2015 Category: Nanotechnology Authors: Tali Ilovitsh, Zeev Zalevsky Tags: Advanced Review Source Type: research

Temporal flickering of contrast agents for enhanced optical imaging
The temporal flickering of contrast agents that labels a biological sample is a unique modality for cellular imaging with single molecule sensitivity. It improves the signal‐to‐noise ratio statistics associated with the noisy in vivo environment and has promising applications in single particle tracking and super‐resolution microscopy techniques. The flickering can be triggered either statistically through the mechanism of temporal fluctuations of the emitter or through external modulation. The enriching toolbox of contrast agents that are feasible for biomedical imaging for the flickering methods will be discussed, ...
Source: Wiley Interdisciplinary Reviews: Nanomedicine and Nanobiotechnology - September 14, 2015 Category: Nanotechnology Authors: Tali Ilovitsh, Zeev Zalevsky Tags: Advanced Review Source Type: research