Corrigendum to 'Neoadjuvant short-course hyperfractionated accelerated radiotherapy (SC-HART) combined with S-1 for locally advanced rectal cancer'
(Source: Journal of Radiation Research)
Source: Journal of Radiation Research - November 11, 2014 Category: Physics Authors: Doi, H., Beppu, N., Odawara, S., Tanooka, M., Takada, Y., Niwa, Y., Fujiwara, M., Kimura, F., Yanagi, H., Yamanaka, N., Kamikonya, N., Hirota, S. Tags: Corrigendum Source Type: research
Lung tumor motion reproducibility for five patients who received four-fraction VMAT stereotactic ablative body radiotherapy under constrained breathing conditions: a preliminary study
(Source: Journal of Radiation Research)
Source: Journal of Radiation Research - November 11, 2014 Category: Physics Authors: Nakagawa, K., Haga, A., Sasaki, K., Kida, S., Masutani, Y., Yamashita, H., Takahashi, W., Igaki, H., Sakumi, A., Ohtomo, K., Yoda, K. Tags: Letter to the Editor Source Type: research
Effective usage of a clearance check to avoid a collision in Gamma Knife Perfexion radiosurgery with the Leksell skull frame
This study sought to develop a simulation method to find the appropriate frame location on the patient's head by retrospective analysis of treatment plans for brain metastasis cases. To validate the accuracy of the collision warning, we compared the collision distance calculated using Leksell GammaPlan (LGP) with actual measured distances. We then investigated isocenter coordinates in near-collision cases using data from 844 previously treated patients and created a clearance map by superimposing them on CT images for just the frame, post and stereotactic fiducial box. The differences in distance between the simulation in ...
Source: Journal of Radiation Research - November 11, 2014 Category: Physics Authors: Nakazawa, H., Tsugawa, T., Mori, Y., Hagiwara, M., Komori, M., Hashizume, C., Shibamoto, Y., Kobayashi, T. Tags: Technology Source Type: research
Geometric accuracy of 3D coordinates of the Leksell stereotactic skull frame in 1.5 Tesla- and 3.0 Tesla-magnetic resonance imaging: a comparison of three different fixation screw materials
We assessed the geometric distortion of 1.5-Tesla (T) and 3.0-T magnetic resonance (MR) images with the Leksell skull frame system using three types of cranial quick fixation screws (QFSs) of different materials—aluminum, aluminum with tungsten tip, and titanium—for skull frame fixation. Two kinds of acrylic phantoms were placed on a Leksell skull frame using the three types of screws, and were scanned with computed tomography (CT), 1.5-T MR imaging and 3.0-T MR imaging. The 3D coordinates for both strengths of MR imaging were compared with those for CT. The deviations of the measured coordinates at selected po...
Source: Journal of Radiation Research - November 11, 2014 Category: Physics Authors: Nakazawa, H., Mori, Y., Yamamuro, O., Komori, M., Shibamoto, Y., Uchiyama, Y., Tsugawa, T., Hagiwara, M. Tags: Technology Source Type: research
Acute urinary morbidity after a permanent 125I implantation for localized prostate cancer
In this study, Du90 and Dup90 were the most significant predictors of AUM after prostate brachytherapy. (Source: Journal of Radiation Research)
Source: Journal of Radiation Research - November 11, 2014 Category: Physics Authors: Ohga, S., Nakamura, K., Shioyama, Y., Tatsugami, K., Sasaki, T., Nonoshita, T., Yoshitake, T., Asai, K., Hirata, H., Naito, S., Honda, H. Tags: Oncology Source Type: research
Neoadjuvant capecitabine, bevacizumab and radiotherapy for locally advanced rectal cancer: results of a single-institute Phase I study
The aim of this Phase I clinical trial was to assess the feasibility and safety of capecitabine-based preoperative chemoradiotherapy (CRT) combined with bevacizumab and to determine the optimal capecitabine dose for Japanese patients with locally advanced rectal cancer. Patients with cT3/T4 rectal cancer were eligible. Bevacizumab was administered at 5 mg/kg intravenously on Days 1, 15 and 29. Capecitabine was administered on weekdays concurrently with pelvic radiotherapy at a daily dose of 1.8 Gy, totally to 50.4 Gy. Capecitabine was initiated at 825 mg/m2 twice daily at Dose Level 1, with a planned escalation to 900 mg/m...
Source: Journal of Radiation Research - November 11, 2014 Category: Physics Authors: Miki, Y., Maeda, K., Hosono, M., Nagahara, H., Hirakawa, K., Shimatani, Y., Tsutsumi, S., Miki, Y. Tags: Oncology Source Type: research
Evaluation of accuracy of B-spline transformation-based deformable image registration with different parameter settings for thoracic images
Deformable image registration (DIR) is fundamental technique for adaptive radiotherapy and image-guided radiotherapy. However, further improvement of DIR is still needed. We evaluated the accuracy of B-spline transformation-based DIR implemented in elastix. This registration package is largely based on the Insight Segmentation and Registration Toolkit (ITK), and several new functions were implemented to achieve high DIR accuracy. The purpose of this study was to clarify whether new functions implemented in elastix are useful for improving DIR accuracy. Thoracic 4D computed tomography images of ten patients with esophageal ...
Source: Journal of Radiation Research - November 11, 2014 Category: Physics Authors: Kanai, T., Kadoya, N., Ito, K., Onozato, Y., Cho, S. Y., Kishi, K., Dobashi, S., Umezawa, R., Matsushita, H., Takeda, K., Jingu, K. Tags: Oncology Source Type: research
Computer-assisted delineation of lung tumor regions in treatment planning CT images with PET/CT image sets based on an optimum contour selection method
To assist radiation oncologists in the delineation of tumor regions during treatment planning for lung cancer, we have proposed an automated contouring algorithm based on an optimum contour selection (OCS) method for treatment planning computed tomography (CT) images with positron emission tomography (PET)/CT images. The basic concept of the OCS is to select a global optimum object contour based on multiple active delineations with a level set method around tumors. First, the PET images were registered to the planning CT images by using affine transformation matrices. The initial gross tumor volume (GTV) of each lung tumor...
Source: Journal of Radiation Research - November 11, 2014 Category: Physics Authors: Jin, Z., Arimura, H., Shioyama, Y., Nakamura, K., Kuwazuru, J., Magome, T., Yabu-Uchi, H., Honda, H., Hirata, H., Sasaki, M. Tags: Oncology Source Type: research
Strength estimation of a moving 125Iodine source during implantation in brachytherapy: application to linked sources
This study sought to demonstrate the feasibility of estimating the source strength during implantation in brachytherapy. The requirement for measuring the strengths of the linked sources was investigated. The utilized sources were 125I with air kerma strengths of 8.38–8.63 U (μGy m2 h–1). Measurements were performed with a plastic scintillator (80 mm x 50 mm x 20 mm in thickness). For a source-to-source distance of 10.5 mm and at source speeds of up to 200 mm s–1, a counting time of 10 ms and a detector-to-needle distance of 5 mm were found to be the appropriate measurement conditions. The combined sta...
Source: Journal of Radiation Research - November 11, 2014 Category: Physics Authors: Tanaka, K., Endo, S., Tateoka, K., Asanuma, O., Hori, M., Takagi, M., Bengua, G., Kamo, K.-i., Sato, K., Takeda, H., Hareyama, M., Sakata, K.-i., Takada, J. Tags: Oncology Source Type: research
Radiotherapy for gastric lymphoma: a planning study of 3D conformal radiotherapy, the half-beam method, and intensity-modulated radiotherapy
This study was conducted to compare the three radiotherapy planning techniques of four-fields 3D conformal radiotherapy (3DCRT), half-field radiotherapy (the half-beam method) and intensity-modulated radiotherapy (IMRT) used to treat primary gastric lymphoma in which the planning target volume (PTV) had a large overlap with the left kidney. A total of 17 patients with gastric diffuse large B-cell lymphoma (DLBCL) were included. In DLBCL, immunochemotherapy (Rituximab + CHOP) was followed by radiotherapy of 40 Gy to the whole stomach and peri-gastric lymph nodes. 3DCRT, the half-field method, and IMRT were compared with res...
Source: Journal of Radiation Research - November 11, 2014 Category: Physics Authors: Inaba, K., Okamoto, H., Wakita, A., Nakamura, S., Kobayashi, K., Harada, K., Kitaguchi, M., Sekii, S., Takahashi, K., Yoshio, K., Murakami, N., Morota, M., Ito, Y., Sumi, M., Uno, T., Itami, J. Tags: Oncology Source Type: research
Development and reproducibility evaluation of a Monte Carlo-based standard LINAC model for quality assurance of multi-institutional clinical trials
Technical developments in radiotherapy (RT) have created a need for systematic quality assurance (QA) to ensure that clinical institutions deliver prescribed radiation doses consistent with the requirements of clinical protocols. For QA, an ideal dose verification system should be independent of the treatment-planning system (TPS). This paper describes the development and reproducibility evaluation of a Monte Carlo (MC)-based standard LINAC model as a preliminary requirement for independent verification of dose distributions. The BEAMnrc MC code is used for characterization of the 6-, 10- and 15-MV photon beams for a wide ...
Source: Journal of Radiation Research - November 11, 2014 Category: Physics Authors: Usmani, M. N., Takegawa, H., Takashina, M., Numasaki, H., Suga, M., Anetai, Y., Kurosu, K., Koizumi, M., Teshima, T. Tags: Oncology Source Type: research
Direct measurement of a patient's entrance skin dose during pediatric cardiac catheterization
In conclusion, we directly measured ESD using RPLD chips and found that maximum ESD could be estimated in real-time using angiographic parameters, such as DAP and cumulative dose at the IRP. Children requiring repeated catheterizations would be exposed to high radiation levels throughout their lives, although treatment influences radiation dose. Therefore, the radiation dose associated with individual cardiac catheterizations should be analyzed, and the effects of radiation throughout the lives of such patients should be followed. (Source: Journal of Radiation Research)
Source: Journal of Radiation Research - November 11, 2014 Category: Physics Authors: Sun, L., Mizuno, Y., Iwamoto, M., Goto, T., Koguchi, Y., Miyamoto, Y., Tsuboi, K., Chida, K., Moritake, T. Tags: Oncology Source Type: research
Dosimetry analyses comparing high-dose-rate brachytherapy, administered as monotherapy for localized prostate cancer, with stereotactic body radiation therapy simulated using CyberKnife
The purpose of this study was to perform dosimetry analyses comparing high-dose-rate brachytherapy (HDR-BT) with simulated stereotactic body radiotherapy (SBRT). We selected six consecutive patients treated with HDR-BT monotherapy in 2010, and a CyberKnife SBRT plan was simulated for each patient using computed tomography images and the contouring set used in the HDR-BT plan for the actual treatment, but adding appropriate planning target volume (PTV) margins for SBRT. Then, dosimetric profiles for PTVs of the rectum, bladder and urethra were compared between the two modalities. The SBRT plan was more homogenous and provid...
Source: Journal of Radiation Research - November 11, 2014 Category: Physics Authors: Fukuda, S., Seo, Y., Shiomi, H., Yamada, Y., Ogata, T., Morimoto, M., Konishi, K., Yoshioka, Y., Ogawa, K. Tags: Oncology Source Type: research
Protective effect of inhalation of hydrogen gas on radiation-induced dermatitis and skin injury in rats
The effect of inhalation of hydrogen-containing gas (1.3% hydrogen + 20.8% oxygen + 77.9% nitrogen) (HCG) on radiation-induced dermatitis and on the healing of healing-impaired skin wounds in rats was examined using a rat model of radiation-induced skin injury. An X-ray dose of 20 Gy was irradiated onto the lower part of the back through two holes in a lead shield. Irradiation was performed before or after inhalation of HCG for 2 h. Inhalation of HCG significantly reduced the severity of radiodermatitis and accelerated healing-impaired wound repair. Staining with terminal deoxynucleotidyl transferase-mediated dUTP nick-end...
Source: Journal of Radiation Research - November 11, 2014 Category: Physics Authors: Watanabe, S., Fujita, M., Ishihara, M., Tachibana, S., Yamamoto, Y., Kaji, T., Kawauchi, T., Kanatani, Y. Tags: Biology Source Type: research
Comparison study of tooth enamel ESR spectra of cows, goats and humans
The ESR radiation dosimetric properties of tooth enamel samples from cows and goats were investigated and compared with those of human samples. Samples were prepared first mechanically, and then chemically. The study results showed that the native signals from cow and goat samples were weaker than those from human samples; the radiation sensitivities for cow and goat samples were very close to those of human tooth enamel samples. These results indicated that cow and goat teeth could be alternative materials for radiation dose estimation. (Source: Journal of Radiation Research)
Source: Journal of Radiation Research - November 11, 2014 Category: Physics Authors: Jiao, L., Liu, Z.-C., Ding, Y.-Q., Ruan, S.-Z., Wu, Q., Fan, S.-J., Zhang, W.-Y. Tags: Biology Source Type: research
