Different dietary energy intake affects skeletal muscle development through an Akt-dependent pathway in Dorper × Small Thin-Tailed crossbred ewe lambs
The objective of this experiment was to investigate the mechanisms through which different levels of dietary energy affect postnatal skeletal muscle development in ewe lambs. Twelve Dorper × Small Thin-Tailed crossbred ewe lambs (100 d of age; 20 ± 0.5 kg BW) were selected randomly and divided into 2 groups in a completely randomized design. Animals were offered identical diets at 100% or 65% of ad libitum intake. Lambs were euthanized when BW in the ad libitum group reached 35 k g and the semitendinosus muscle was sampled. (Source: Domestic Animal Endocrinology)
Source: Domestic Animal Endocrinology - May 26, 2016 Category: Endocrinology Authors: J.X. Zhao, X.D. Liu, K. Li, W.Z. Liu, Y.S. Ren, J.X. Zhang Source Type: research

Diagnosis of prediabetes in cats: glucose concentration cut points for impaired fasting glucose and impaired glucose tolerance
The objective of the study was to establish methodology and cut points for fasting and 2-h blood glucose concentrations in healthy client-owned senior cats (≥8 yr) using ear/paw samples and a portable glucose meter calibrated for feline blood. Of the 78 cats, 27 were ideal (body condition score [BCS] 4 or 5 of 9), 31 overweight (BCS 6 or 7), and 20 obese (BCS 8 or 9); 19 were Burmese and 59 non-Burmese. (Source: Domestic Animal Endocrinology)
Source: Domestic Animal Endocrinology - May 26, 2016 Category: Endocrinology Authors: M.K. Reeve-Johnson, J.S. Rand, D. Vankan, S.T. Anderson, R. Marshall, J.M. Morton Source Type: research

Dosing obese cats based on body weight spuriously affects some measures of glucose tolerance
The primary objective was to investigate whether dosing glucose by body weight results in spurious effects on measures of glucose tolerance in obese cats, because volume of distribution does not increase linearly with body weight. Healthy research cats (n = 16; 6 castrated males, 10 spayed females) were used. A retrospective study was performed using glucose concentration data from glucose tolerance and insulin sensitivity tests before and after cats were fed ad libitum for 9 to 12 mo to promote weight gain. (Source: Domestic Animal Endocrinology)
Source: Domestic Animal Endocrinology - May 26, 2016 Category: Endocrinology Authors: M.K. Reeve-Johnson, J.S. Rand, S.T. Anderson, D.J. Appleton, J.M. Morton, D. Vankan Source Type: research

Diagnosis of prediabetes in cats: glucose concentration cutpoints for impaired fasting glucose and impaired glucose tolerance
The objective of the study was to establish methodology and cutpoints for fasting and 2-h blood glucose concentrations in healthy client-owned senior cats (> 8 yrs) using ear/ paw samples and a portable glucose meter calibrated for feline blood. Of the 78 cats, 27 were ideal (body condition score (BCS) 4 or 5 out of 9), 31 overweight (BCS 6 or 7) and 20 obese (BCS 8 or 9); 19 were Burmese and 59 non-Burmese. (Source: Domestic Animal Endocrinology)
Source: Domestic Animal Endocrinology - May 26, 2016 Category: Endocrinology Authors: M.K. Reeve-Johnson, J.S. Rand, D. Vankan, S.T. Anderson, R. Marshall, J.M. Morton Source Type: research

Temporal relationships between minor, preovulatory, or periovulatory FSH surges and the emergence and development of 2-mm follicles of wave 1 in Bos taurus heifers
The number and day of emergence (first detection) of 2-mm follicles and the number and day when the 2-mm follicles reached 3-, 4-, 5-, and 6-mm during wave 1 were determined every 0.5 d (n = 9 heifers). Emergence of the follicles at each of the indicated diameters was normalized to the beginning and ending nadir and the peak of each of a minor FSH surge, the preovulatory surge and the periovulatory surge. Relative to the day of ovulation (Day 0), the minor FSH surge, preovulatory surge, and periovulatory surge encompassed (nadir to nadir) Days −7.0 to −2.5 (peak, Day −4.0), Days −2.5 to −0.5 (peak, Day −1.0), a...
Source: Domestic Animal Endocrinology - May 26, 2016 Category: Endocrinology Authors: J.M. Baldrighi, M.A.R. Siddiqui, O.J. Ginther Source Type: research

Different dietary energy intake affects skeletal muscle development through an Akt-dependent pathway in Dorper × Small Thin-Tailed crossbred ewe lambs
The objective of this experiment was to investigate the mechanisms through which different levels of dietary energy affect postnatal skeletal muscle development in ewe lambs. Twelve Dorper × Small Thin-Tailed crossbred ewe lambs (100 d of age; 20 ± 0.5 kg body weight, BW) were selected randomly and divided into two groups in a completely randomized design. Animals were offered identical diets at 100% or 65% of ad libitum intake. Lambs were euthanized when BW in the ad libitum group reached 35 kg, and the semitendinosus (ST) muscle was sampled. (Source: Domestic Animal Endocrinology)
Source: Domestic Animal Endocrinology - May 26, 2016 Category: Endocrinology Authors: J.X. Zhao, X.D. Liu, K. Li, W.Z. Liu, Y.S. Ren, J.X. Zhang Source Type: research

Molecular cloning, expression analysis, and function of decorin in goat ovarian granulosa cells
This study cloned the full-length cDNA of goat DCN obtained from the ovary of an adult goat. Sequence analysis revealed that the putative DCN protein shared a highly conserved amino acid sequence with known mammalian homologs. The tissue distribution of DCN mRNA expression was evaluated by real-time PCR, and the results showed that DCN was widely expressed in the tissues of adult goat. (Source: Domestic Animal Endocrinology)
Source: Domestic Animal Endocrinology - May 24, 2016 Category: Endocrinology Authors: J.Y. Peng, K.X. Gao, H.Y. Xin, P. Han, G.Q. Zhu, B.Y. Cao Source Type: research

Molecular cloning, expression analysis, and function of decorin in goat ovarian granulosa cells
This study cloned the full-length cDNA of goat DCN obtained from the ovary of an adult goat. Sequence analysis revealed that the putative DCN protein shared a highly conserved amino acid sequence with known mammalian homologs. The tissue distribution of DCN mRNA expression was evaluated by real-time PCR, and results showed that DCN was widely expressed in the tissues of adult goat. (Source: Domestic Animal Endocrinology)
Source: Domestic Animal Endocrinology - May 24, 2016 Category: Endocrinology Authors: J.Y. Peng, K.X. Gao, H.Y. Xin, P. Han, G.Q. Zhu, B.Y. Cao Source Type: research

Preface: Eighth International Conference on Farm Animal Endocrinology
The review articles of the present special issue of Domestic Animal Endocrinology are based on invited talks presented at the eighth International Conference on Farm Animal Endocrinology (ICFAE), which took place from 27 to 29 August 2015 at Hotel Legoland, Billund, Denmark. A total of 80 scientists participated in the conference and witnessed high-quality talks and poster presentations arranged into 5 scientific sessions (1) Endocrine control of metabolism, (2) the gut: new critical control points for endocrine-immune-metabolic targeting, (3) animal health and stress: consequences and strategies, (4) endocrine control of...
Source: Domestic Animal Endocrinology - May 19, 2016 Category: Endocrinology Authors: Mogens Vestergaard, Rupert Bruckmaier, Akio Miyamoto, organizing committee Source Type: research

8th International Conference on Farm Animal Endocrinology
The review articles of the present special issue of Domestic Animal Endocrinology are based on invited talks presented at the 8th International Conference on Farm Animal Endocrinology (ICFAE), which took place 27-29 August 2015 at Hotel Legoland, Billund, Denmark. A total of 80 scientists participated in the conference and witnessed high-quality talks and poster presentations arranged into five scientific sessions; 1: Endocrine control of metabolism, 2: The gut: New critical control points for endocrine-immune-metabolic targeting, 3: Animal Health and stress: consequences and strategies, 4: Endocrine control of lactation, ...
Source: Domestic Animal Endocrinology - May 19, 2016 Category: Endocrinology Authors: Mogens Vestergaard, Rupert Bruckmaier, Akio Miyamoto Source Type: research

Changes in acyl and total ghrelin concentrations and their association with dry matter intake, average daily gain, and feed efficiency of finishing beef steers and heifers
The objective of this experiment was to determine the change in acyl ghrelin, total ghrelin, and the ghrelin ratio (acyl ghrelin/total ghrelin) over an 84-d DMI and average daily BW gain (ADG) measurement period and to determine the association of those ghrelin measurements with DMI, ADG, ADG:DMI ratio (G:F), and residual feed intake in finishing beef steers and heifers. (Source: Domestic Animal Endocrinology)
Source: Domestic Animal Endocrinology - May 17, 2016 Category: Endocrinology Authors: A.P. Foote, K.E. Hales, H.C. Freetly Source Type: research

Changes in acyl and total ghrelin concentrations and their association with dry matter intake, average daily gain, and feed efficiency of finishing beef steers and heifers
The objective of this experiment was to determine the change in acyl ghrelin, total ghrelin, and the ghrelin ratio (acyl ghrelin/total ghrelin) over an 84-d DMI and average daily BW gain (ADG) measurement period and to determine the association of those ghrelin measurements with DMI, ADG, ADG:DMI ratio (G:F), and residual feed intake (RFI) in finishing beef steers and heifers. (Source: Domestic Animal Endocrinology)
Source: Domestic Animal Endocrinology - May 17, 2016 Category: Endocrinology Authors: A.P. Foote, K.E. Hales, H.C. Freetly Source Type: research

A transcriptional cofactor YAP regulates IFNT expression via transcription factor TEAD in bovine conceptuses
Interferon tau (IFNT) is the pregnancy recognition protein in all ruminants, and its expression is restricted to trophoblast cells. Interferon tau production increases as the conceptus elongates; however, its expression is downregulated soon after the initiation of conceptus attachment to the uterine epithelium. Our previous study identified that among 8 bovine IFNT genes, only 2 forms of IFNTs, IFNT2 and IFN-tau-c1, were expressed by the conceptuses during the periattachment period. To characterize whether Hippo signaling including a transcription cofactor yes-associated protein (YAP) was involved in the IFNT regulation, ...
Source: Domestic Animal Endocrinology - May 16, 2016 Category: Endocrinology Authors: K. Kusama, R. Bai, T. Sakurai, H. Bai, A. Ideta, Y. Aoyagi, K. Imakawa Source Type: research

A transcriptional co-factor YAP regulates IFNT expression via transcription factor TEAD in bovine conceptuses
Interferon tau (IFNT) is the pregnancy recognition protein in all ruminants and its expression is restricted to trophoblast cells. IFNT production increases as the conceptus elongates, however, its expression is down-regulated soon after the initiation of conceptus attachment to the uterine epithelium. Our previous study identified that among eight bovine IFNT genes, only two forms of IFNTs, IFNT2 and IFN-tau-c1, were expressed by the conceptuses during the peri-attachment period. To characterize whether Hippo signaling including a transcription co-factor Yes associated protein (YAP) was involved in the IFNT regulation, we...
Source: Domestic Animal Endocrinology - May 16, 2016 Category: Endocrinology Authors: K. Kusama, R. Bai, T. Sakurai, H. Bai, A. Ideta, Y. Aoyagi, K. Imakawa Source Type: research