Birth Defects Research Part A: Clinical and Molecular Teratology This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

EFTUD2 deficiency in vertebrates: Identification of a novel human mutation and generation of a zebrafish model
ConclusionThis study reports a novel mutation in EFTUD2 in a Mandibulofacial Dysostosis, Guion‐Almeida type patient with unusual ocular features and the generation of a first animal model of eftud2 deficiency. The severe embryonic phenotype observed in eftud2 mutants indicates an important conserved role during development of diverse tissues in vertebrates. Birth Defects Research (Part A), 2015. © 2015 Wiley Periodicals, Inc. (Source: Birth Defects Research Part A: Clinical and Molecular Teratology)
Source: Birth Defects Research Part A: Clinical and Molecular Teratology - June 1, 2015 Category: Perinatology & Neonatology Authors: Brett Deml, Linda M. Reis, Sanaa Muheisen, David Bick, Elena V. Semina Tags: Original Research Article Source Type: research

Findings from the National Birth Defects Prevention Study: Interpretation and translation for the clinician
ConclusionThe NBDPS has continued to play an important role as a rich U.S. data source that can advance the understanding of maternal conditions and their treatments in relation to birth defects. Birth Defects Research (Part A), 2015. © 2015 Wiley Periodicals, Inc. (Source: Birth Defects Research Part A: Clinical and Molecular Teratology)
Source: Birth Defects Research Part A: Clinical and Molecular Teratology - June 1, 2015 Category: Perinatology & Neonatology Authors: Sura Alwan, Christina D. Chambers Tags: Original Research Article Source Type: research

Using the electronic medical record to refer women taking category D or X medications for teratogen and contraceptive counseling
ConclusionCreating an EMR alert and referral system for women prescribed category X or D medications is feasible. Counseling on teratogen exposure and contraception may improve the acceptability of more effective contraception. Birth Defects Research (Part A), 2015. © 2015 Wiley Periodicals, Inc. (Source: Birth Defects Research Part A: Clinical and Molecular Teratology)
Source: Birth Defects Research Part A: Clinical and Molecular Teratology - June 1, 2015 Category: Perinatology & Neonatology Authors: Sheila K. Mody, Jennifer Wu, Marla Ornelas, Colleen Kernahan, Elizabeth Salas, Kelly Kao, Robert Felix, Christina Chambers Tags: Brief Report Source Type: research

Unusual trend in the prevalence of trisomy 13 in mothers aged 35 and older: A population based study of national congenital anomaly data
ConclusionThe unexpected declining trend in trisomy 13 in older mothers could not be explained by the risk factors examined in this study. There have been no other reports of trends in the prevalence of trisomy 13 in older mothers in recent years. There is further need for surveillance of trends in future and in other populations. Birth Defects Research (Part A), 2014. © 2015 Wiley Periodicals, Inc. (Source: Birth Defects Research Part A: Clinical and Molecular Teratology)
Source: Birth Defects Research Part A: Clinical and Molecular Teratology - June 1, 2015 Category: Perinatology & Neonatology Authors: Deepa Balachandran Nair, David Tucker, Rhian Hughes, Judith Greenacre, Margery Morgan Tags: Original Research Article Source Type: research

Periconceptional changes in weight and risk of delivering offspring with conotruncal heart defects
ConclusionGiven current recommendations about limited weight gain for obese pregnant women, these data indicate that dieting may not substantially increase a fetus' risk of having a conotruncal defect. Birth Defects Research (Part A), 2015. © 2015 Wiley Periodicals, Inc. (Source: Birth Defects Research Part A: Clinical and Molecular Teratology)
Source: Birth Defects Research Part A: Clinical and Molecular Teratology - May 28, 2015 Category: Perinatology & Neonatology Authors: Emily Hawkins Carter, Suzan L. Carmichael, Krista Birnie, Wei Yang, Edward J. Lammer, Gary M. Shaw Tags: Original Research Article Source Type: research

Maternal factors in the origin of isolated oesophageal atresia: A population‐based case–control study
Conclusion: First delivery, lower socioeconomic status, acute respiratory diseases and essential hypertension treated with nifedipine in the mothers may associate with a higher risk for IOA in their children. Birth Defects Research (Part A), 2015. © 2015 Wiley Periodicals, Inc. (Source: Birth Defects Research Part A: Clinical and Molecular Teratology)
Source: Birth Defects Research Part A: Clinical and Molecular Teratology - May 28, 2015 Category: Perinatology & Neonatology Authors: Gábor Vermes, Ákos Mátrai, Andrew E. Czeizel, Nándor Ács Tags: Original Research Article Source Type: research

55th Annual Teratology Society Meeting
(Source: Birth Defects Research Part A: Clinical and Molecular Teratology)
Source: Birth Defects Research Part A: Clinical and Molecular Teratology - May 19, 2015 Category: Perinatology & Neonatology Tags: 55th Annual Teratology Society Meeting Source Type: research

Issue information
(Source: Birth Defects Research Part A: Clinical and Molecular Teratology)
Source: Birth Defects Research Part A: Clinical and Molecular Teratology - May 19, 2015 Category: Perinatology & Neonatology Tags: Issue Information Source Type: research

Population‐based study of hospital costs for hospitalizations of infants, children, and adults with a congenital heart defect, Arkansas 2006 to 2011
ConclusionHospitalizations with CHDs account for a disproportionate share of hospital costs in Arkansas. Hospitalizations of children with CHD accounted for a higher proportion of total hospitalizations than did hospitalizations of adults with CHD. Birth Defects Research (Part A), 2015. © 2015 Wiley Periodicals, Inc. (Source: Birth Defects Research Part A: Clinical and Molecular Teratology)
Source: Birth Defects Research Part A: Clinical and Molecular Teratology - May 1, 2015 Category: Perinatology & Neonatology Authors: Regina M. Simeone, Matthew E. Oster, Charlotte A. Hobbs, James M. Robbins, R. Thomas Collins, Margaret A. Honein Tags: Brief Report Source Type: research

Association between polymorphisms at the GREM1 locus and the risk of nonsyndromic cleft lip with or without cleft palate in the Polish population
ConclusionOur results might suggest that variants influencing GREM1 expression levels, rather than variants affecting the function of the encoded protein, are significant factors in NSCL/P etiology. Birth Defects Research (Part A), 2015. © 2015 Wiley Periodicals, Inc. (Source: Birth Defects Research Part A: Clinical and Molecular Teratology)
Source: Birth Defects Research Part A: Clinical and Molecular Teratology - May 1, 2015 Category: Perinatology & Neonatology Authors: Adrianna Mostowska, Kamil K. Hozyasz, Piotr Wójcicki, Kacper Żukowski, Anna Dąbrowska, Agnieszka Lasota, Małgorzata Zadurska, Agnieszka Radomska, Izabela Dunin‐Wilczyńska, Paweł P. Jagodziński Tags: Original Research Article Source Type: research

The national birth defects prevention study: A review of the methods
ConclusionThe NBDPS has made substantial contributions to the field of birth defects epidemiology through its rigorous design, including case classification, detailed questionnaire and specimen collection, large study population, and collaborative activities across Centers. Birth Defects Research (Part A), 2015. © 2015 Wiley Periodicals, Inc. (Source: Birth Defects Research Part A: Clinical and Molecular Teratology)
Source: Birth Defects Research Part A: Clinical and Molecular Teratology - May 1, 2015 Category: Perinatology & Neonatology Authors: Jennita Reefhuis, Suzanne M. Gilboa, Marlene Anderka, Marilyn L. Browne, Marcia L. Feldkamp, Charlotte A. Hobbs, Mary M. Jenkins, Peter H. Langlois, Kimberly B. Newsome, Andrew F. Olshan, Paul A. Romitti, Stuart K. Shapira, Gary M. Shaw, Sarah C. Tinker, Tags: Research Article Source Type: research

Developments in our understanding of the genetic basis of birth defects
We describe genotyping and sequencing methods for the detection and analysis of rare and common variants. We remark on the utility of model organisms and explore epigenetics in the context of structural malformation. We conclude by highlighting approaches that may provide insight into the complex genetics of birth defects. Birth Defects Research (Part A), 2015. © 2015 Wiley Periodicals, Inc. (Source: Birth Defects Research Part A: Clinical and Molecular Teratology)
Source: Birth Defects Research Part A: Clinical and Molecular Teratology - May 1, 2015 Category: Perinatology & Neonatology Authors: Daniel M. Webber, Stewart L. MacLeod, Michael J. Bamshad, Gary M. Shaw, Richard H. Finnell, Sanjay S. Shete, John S. Witte, Stephen W. Erickson, Linda D. Murphy, Charlotte Hobbs Tags: Review Article Source Type: research

Detecting gene–environment interactions in human birth defects: Study designs and statistical methods
ConclusionA range of approaches can be used to evaluate potentially important G×E effects in the NBDPS. Investigators should be aware of the limitations inherent to each approach when choosing a study design and interpreting results. Birth Defects Research (Part A), 2015. © 2015 Wiley Periodicals, Inc. (Source: Birth Defects Research Part A: Clinical and Molecular Teratology)
Source: Birth Defects Research Part A: Clinical and Molecular Teratology - May 1, 2015 Category: Perinatology & Neonatology Authors: Caroline G. Tai, Rebecca E. Graff, Jinghua Liu, Michael N. Passarelli, Joel A. Mefford, Gary M. Shaw, Thomas J. Hoffmann, John S. Witte Tags: Research Article Source Type: research

Preventing folate‐related neural tube defects: Problem solved, or not?
(Source: Birth Defects Research Part A: Clinical and Molecular Teratology)
Source: Birth Defects Research Part A: Clinical and Molecular Teratology - April 17, 2015 Category: Perinatology & Neonatology Authors: James L. Mills Tags: Editorial Source Type: research

U.S. women of childbearing age who are at possible increased risk of a neural tube defect‐affected pregnancy due to suboptimal red blood cell folate concentrations, National Health and Nutrition Examination Survey 2007 to 2012
ConclusionBased on RBC folate concentrations, we would predict that the majority of U.S. women of reproductive age are not at increased risk for folate sensitive NTDs in the presence of mandatory folic acid fortification. Prevention policies and programs can be aimed at population subgroups identified as having higher predicted risk for folate‐sensitive NTDs based on RBC folate concentrations. Birth Defects Research (Part A), 2015. © 2015 Wiley Periodicals, Inc. (Source: Birth Defects Research Part A: Clinical and Molecular Teratology)
Source: Birth Defects Research Part A: Clinical and Molecular Teratology - April 17, 2015 Category: Perinatology & Neonatology Authors: Sarah C. Tinker, Heather C. Hamner, Yan Ping Qi, Krista S. Crider Tags: Original Research Article Source Type: research