Developments in our understanding of the genetic basis of birth defects

We describe genotyping and sequencing methods for the detection and analysis of rare and common variants. We remark on the utility of model organisms and explore epigenetics in the context of structural malformation. We conclude by highlighting approaches that may provide insight into the complex genetics of birth defects. Birth Defects Research (Part A), 2015. © 2015 Wiley Periodicals, Inc.

Source: Birth Defects Research Part A: Clinical and Molecular Teratology - May 1, 2015 Category: Perinatology & Neonatology Authors: Daniel M. Webber, Stewart L. MacLeod, Michael J. Bamshad, Gary M. Shaw, Richard H. Finnell, Sanjay S. Shete, John S. Witte, Stephen W. Erickson, Linda D. Murphy, Charlotte Hobbs Tags: Review Article Source Type: research