Birth Defects Research Part A: Clinical and Molecular Teratology This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

Congenital anomalies of the kidney and the urinary tract: A murmansk county birth registry study
CONCLUSIONThe overall fourfold enhancement of the occurrence of urinary malformations in Murmansk County for the 2006 to 2011 period showed little annual dependence. During pregnancy, use of medications, infections, pre‐existing diabetes mellitus, or gestational diabetes were associated with increased risk of these anomalies, as was conception during summer. Our findings have direct applications in improving prenatal care in Murmansk County and establishing targets for prenatal screening and women's consultations. Birth Defects Research (Part A), 2016. © 2016 Wiley Periodicals, Inc. (Source: Birth Defects Research Part ...
Source: Birth Defects Research Part A: Clinical and Molecular Teratology - January 1, 2016 Category: Perinatology & Neonatology Authors: Vitaly A. Postoev, Andrej M. Grjibovski, Anton A. Kovalenko, Erik Eik Anda, Evert Nieboer, Jon Øyvind Odland Tags: Original Research Article Source Type: research

Acardiac twinning: High resolution three‐dimensional reconstruction of a low resistance case
ConclusionOur case showed a small acardiac mass with large diameter vessels and consequential low outflow resistance that caused pump twin complications. This indicates that the development of a method that allows pump twin prognosis is likely more successful if based on the use of acardiac versus pump twin perfusion flows than on body volume ratios. Birth Defects Research (Part A), 2015. © 2015 Wiley Periodicals, Inc. (Source: Birth Defects Research Part A: Clinical and Molecular Teratology)
Source: Birth Defects Research Part A: Clinical and Molecular Teratology - December 21, 2015 Category: Perinatology & Neonatology Authors: Monique G.J.T.B. Lier, Enrico Lopriore, Frank P.H.A. Vandenbussche, Geert J. Streekstra, Maria Siebes, Peter G.J. Nikkels, Dick Oepkes, Martin J.C. Gemert, Jeroen P.H.M. Wijngaard Tags: Brief Report Source Type: research

Impact of prenatal diagnosis on the outcome of patients with a transposition of great arteries: A 24‐year population‐based study
ConclusionWe demonstrated that prenatal diagnosis and neonatal mortality of TGA varied greatly according to the malformation type and the study period. This could be explained by an improvement in terms of medical management. Birth Defects Research (Part A), 2015. © 2015 Wiley Periodicals, Inc. (Source: Birth Defects Research Part A: Clinical and Molecular Teratology)
Source: Birth Defects Research Part A: Clinical and Molecular Teratology - December 21, 2015 Category: Perinatology & Neonatology Authors: Anne Debost‐Legrand, Lemlih Ouchchane, Christine Francannet, Carole Goumy, Isabelle Perthus, Anne‐Marie Beaufrère, Denis Gallot, Didier Lemery, Jean‐René Lusson, Hélène Laurichesse‐Delmas Tags: Original Research Article Source Type: research

Hospitalization charges for children with birth defects in Texas, 2001 to 2010
ConclusionCharges associated with these conditions are far greater than those associated with pediatric hospitalizations for other causes, whether in the newborn period or beyond. However, these charges vary depending on specific diagnoses, expected payer source, and year of treatment. Birth Defects Research (Part A), 2015. © 2015 Wiley Periodicals, Inc. (Source: Birth Defects Research Part A: Clinical and Molecular Teratology)
Source: Birth Defects Research Part A: Clinical and Molecular Teratology - December 21, 2015 Category: Perinatology & Neonatology Authors: Karen B. Moffitt, Amy P. Case, Noha H. Farag, Mark A. Canfield Tags: Original Research Article Source Type: research

Parental risk factors of anorectal malformations: Analysis with a regional population‐based control group
ConclusionThis study suggests an association between the occurrence of ARMs in the offspring and periconceptional maternal smoking as well as maternal chronic respiratory diseases. In addition, there might be a sign of an association for maternal diabetes, although not statistically significant. It can be assumed that the power is far too low to provide reliable estimates. Birth Defects Research (Part A), 2015. © 2015 Wiley Periodicals, Inc. (Source: Birth Defects Research Part A: Clinical and Molecular Teratology)
Source: Birth Defects Research Part A: Clinical and Molecular Teratology - December 21, 2015 Category: Perinatology & Neonatology Authors: Nadine Zwink, Anke Rissmann, Simone Pötzsch, Heiko Reutter, Ekkehart Jenetzky, Tags: Original Research Article Source Type: research

Residential agricultural pesticide exposures and risks of selected birth defects among offspring in the San Joaquin Valley of California
ConclusionFor groups, these ORs were for anotia/microtia (n = 95 cases) and dichlorophenoxy acids/esters and neonicotinoids; anorectal atresia/stenosis (n = 77) and alcohol/ethers and organophosphates (these ORs were < 1.0); transverse limb deficiencies (n = 59) and dichlorophenoxy acids/esters, petroleum derivatives, and triazines; and craniosynostosis (n = 79) and alcohol/ethers, avermectins, neonicotinoids, and organophosphates. For chemicals, ORs were: anotia/microtia and five pesticides from the groups dichlorophenoxy acids/esters, copper‐containing compounds, neonicotinoids, organophosphates,...
Source: Birth Defects Research Part A: Clinical and Molecular Teratology - December 21, 2015 Category: Perinatology & Neonatology Authors: Suzan L. Carmichael, Wei Yang, Eric Roberts, Susan E. Kegley, Timothy J. Brown, Paul B. English, Edward J. Lammer, Gary M. Shaw Tags: Original Research Article Source Type: research

High doses of alcohol during pregnancy cause DNA damages in osteoblasts of newborns rats
ConclusionOur results showed that prenatal exposure to ethanol induced DNA damage in osteoblasts, as shown by micronucleus formation and higher percentage of DNA in the comet tail. It can be concluded that prenatal exposure to ethanol damages osteoblast DNA in newborns exposed to high doses of ethanol during pregnancy, suggesting that prenatal ethanol consumption has a direct effect on fetal osteoblasts. Birth Defects Research (Part A), 2015. © 2015 Wiley Periodicals, Inc. (Source: Birth Defects Research Part A: Clinical and Molecular Teratology)
Source: Birth Defects Research Part A: Clinical and Molecular Teratology - December 21, 2015 Category: Perinatology & Neonatology Authors: Isabel Chaves Silva Carvalho, Tamires Pereira Dutra, Dennia Perez De Andrade, Ivan Balducci, Cristina Pacheco‐Soares, Rosilene Fernandes da Rocha Tags: Original Research Article Source Type: research

Epidemiologic characteristics and time trend in the prevalence of anotia and microtia in China
ConclusionAn increasing trend of the birth prevalence of anotia and microtia is observed in China. Higher prevalence risk of isolated anotia and microtia is found among western births, mothers residing in urban areas, older mothers, and males. Birth Defects Research (Part A), 2015. © 2015 Wiley Periodicals, Inc. (Source: Birth Defects Research Part A: Clinical and Molecular Teratology)
Source: Birth Defects Research Part A: Clinical and Molecular Teratology - December 17, 2015 Category: Perinatology & Neonatology Authors: Kui Deng, Li Dai, Ling Yi, Changfei Deng, Xiaohong Li, Jun Zhu Tags: Original Research Article Source Type: research

Issue Information
(Source: Birth Defects Research Part A: Clinical and Molecular Teratology)
Source: Birth Defects Research Part A: Clinical and Molecular Teratology - December 14, 2015 Category: Perinatology & Neonatology Tags: Issue Information Source Type: research

Clinical, genetic and neuropathological findings in a series of 138 fetuses with a corpus callosum malformation
CONCLUSIONIn our series of 138 cases of CCM, prenatal and postmortem examinations identified a variety of genetic causes. However, no diagnosis could be established in 67% of cases. The classification based on the underlying neurodevelopmental defects paves the way for further genetic studies and genotype‐phenotype correlations. Birth Defects Research (Part A), 2015. © 2015 Wiley Periodicals, Inc. (Source: Birth Defects Research Part A: Clinical and Molecular Teratology)
Source: Birth Defects Research Part A: Clinical and Molecular Teratology - December 14, 2015 Category: Perinatology & Neonatology Authors: Caroline Alby, Valérie Malan, Lucile Boutaud, Maria Angela Marangoni, Bettina Bessières, Maryse Bonniere, Amale Ichkou, Nadia Elkhartoufi, Nadia Bahi‐Buisson, Pascale Sonigo, Anne‐Elodie Millischer, Sophie Thomas, Yves Ville, Michel Vekemans, Férec Tags: Obituary Source Type: research

Cell death and cell proliferation in human spina bifida
ConclusionIn conclusion, this study confirms the fundamental role of cell death/proliferation balance during central nervous system development and reports the changing expression of LC3 protein in mouse and human neural tube. Birth Defects Research (Part A), 2015. © 2015 Wiley Periodicals, Inc. (Source: Birth Defects Research Part A: Clinical and Molecular Teratology)
Source: Birth Defects Research Part A: Clinical and Molecular Teratology - December 10, 2015 Category: Perinatology & Neonatology Authors: Laura Avagliano, Patrizia Doi, Delfina Tosi, Valeria Scagliotti, Angelica Gualtieri, Carles Gaston‐Massuet, Anna Pistocchi, Andrea Gallina, Anna Maria Marconi, Gaetano Bulfamante, Valentina Massa Tags: Research Article Source Type: research

BDRA Reviewer Thank You 2015
(Source: Birth Defects Research Part A: Clinical and Molecular Teratology)
Source: Birth Defects Research Part A: Clinical and Molecular Teratology - December 1, 2015 Category: Perinatology & Neonatology Tags: Editorial Source Type: research

Association between maternal aluminum exposure and the risk of congenital heart defects in offspring
ConclusionA high maternal aluminum concentration may significantly increase the risk of delivering a child with a CHD, such as a septal defect, conotruncal heart defect and right‐side obstruction. Birth Defects Research (Part A), 2015. © 2015 Wiley Periodicals, Inc. (Source: Birth Defects Research Part A: Clinical and Molecular Teratology)
Source: Birth Defects Research Part A: Clinical and Molecular Teratology - December 1, 2015 Category: Perinatology & Neonatology Authors: Zhen Liu, Yuan Lin, Xiaoxian Tian, Jun Li, Xinlin Chen, Jiaxiang Yang, Xiaohong Li, Ying Deng, Nana Li, Juan Liang, Shengli Li, Jun Zhu Tags: Original Research Article Source Type: research

Hypothesis acardiac twin pregnancies: Pathophysiology‐based hypotheses suggest risk prediction by pump/acardiac umbilical venous diameter ratios
CONCLUSIONOur data provide first evidence that UVD‐ratios allow risk prediction of pump twins. More early uncomplicated and late complicated cases are needed, for example, in a prospective trial, before the separation between uncomplicated and complicated cohorts is accurate enough to support a well‐founded decision on (early) intervention. Birth Defects Research (Part A), 2015. © 2015 Wiley Periodicals, Inc. (Source: Birth Defects Research Part A: Clinical and Molecular Teratology)
Source: Birth Defects Research Part A: Clinical and Molecular Teratology - December 1, 2015 Category: Perinatology & Neonatology Authors: Martin J.C. van Gemert, Lourens R. Pistorius, Kurt Benirschke, Gouke J. Bonsel, Frank P.H.A. Vandenbussche, K. Marieke Paarlberg, Jeroen P.H.M. van den Wijngaard, Peter G.J. Nikkels Tags: Hypothesis Source Type: research

Array‐based molecular karyotyping in fetal brain malformations: Identification of novel candidate genes and chromosomal regions
CONCLUSIONOur study suggests chromosomal regions 1q25.1, 5q35.1, 6q25.3‐qter, 11p14.3, 15q11.2‐q13.1, and 18q21.1 to be involved in human brain development. Within three of these regions, we suggest UBTD2, GPR52, and SKA1 as possible candidate genes. Because the overall detection rate of array‐based molecular karyotyping was slightly higher (23%) than that of conventional prenatal karyotyping (20%), we suggest it's use for prenatal diagnostic testing in fetuses with nonisolated brain malformations. Birth Defects Research (Part A), 2015. © 2015 Wiley Periodicals, Inc. (Source: Birth Defects Research Part A: Clinical ...
Source: Birth Defects Research Part A: Clinical and Molecular Teratology - December 1, 2015 Category: Perinatology & Neonatology Authors: Sophia K. Krutzke, Hartmut Engels, Andrea Hofmann, Madita M. Schumann, Kirsten Cremer, Alexander M. Zink, Alina Hilger, Michael Ludwig, Ulrich Gembruch, Heiko Reutter, Waltraut M. Merz Tags: Original Research Article Source Type: research