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Editorial utility of population‐based birth defects surveillance for monitoring the health of infants and as a foundation for etiologic research
(Source: Birth Defects Research Part A: Clinical and Molecular Teratology)
Source: Birth Defects Research Part A: Clinical and Molecular Teratology - September 1, 2015 Category: Perinatology & Neonatology Authors: Cynthia A. Moore, Edward R.B. McCabe Tags: Editorial Source Type: research

Maternal asthma medication use during pregnancy and risk of congenital heart defects
ConclusionWe did not observe statistically significant associations between the reported use of asthma medications during pregnancy and most specific types of CHDs. Despite limitations in our inability to evaluate asthma status and severity, our study suggests that maternal asthma medication use does not substantially, if at all, increase the risk of CHDs. Birth Defects Research (Part A), 2015. © 2015 Wiley Periodicals, Inc. (Source: Birth Defects Research Part A: Clinical and Molecular Teratology)
Source: Birth Defects Research Part A: Clinical and Molecular Teratology - September 1, 2015 Category: Perinatology & Neonatology Authors: Alissa R. Van Zutphen, Erin M. Bell, Marilyn L. Browne, Shao Lin, Angela E. Lin, Charlotte M. Druschel, Tags: Original Research Article Source Type: research

Interpregnancy interval and birth defects
ConclusionA long interpregnancy interval is an independent risk factor for birth defects. It may be helpful for maternal and child health programs and health care providers to highlight the deleterious effects of a long interpregnancy interval. Birth Defects Research (Part A), 2015. © 2015 Wiley Periodicals, Inc. (Source: Birth Defects Research Part A: Clinical and Molecular Teratology)
Source: Birth Defects Research Part A: Clinical and Molecular Teratology - September 1, 2015 Category: Perinatology & Neonatology Authors: Adel Mburia‐Mwalili, Wei Yang Tags: Original Research Article Source Type: research

Low‐dose maternal warfarin intake resulting in fetal warfarin syndrome: In search for a safe anticoagulant regimen during pregnancy
ConclusionWe emphasize the need for optimizing the choice and dosage schedule of anticoagulants during pregnancy, least harmful for the mother and her developing fetus. Birth Defects Research (Part A), 2015. © 2015 Wiley Periodicals, Inc. (Source: Birth Defects Research Part A: Clinical and Molecular Teratology)
Source: Birth Defects Research Part A: Clinical and Molecular Teratology - September 1, 2015 Category: Perinatology & Neonatology Authors: Sriparna Basu, Priyanka Aggarwal, Neha Kakani, Ashok Kumar Tags: Brief Report Source Type: research

Role of the planar cell polarity gene Protein tyrosine kinase 7 in neural tube defects in humans
ConclusionWe detected potentially pathogenic PTK7 variants in 1.1% of our NTD cohort. Our findings implicate PTK7 as a risk factor for NTDs and provide additional evidence for a pathogenic role of PCP signaling in these malformations. Birth Defects Research (Part A), 2015. © 2015 Wiley Periodicals, Inc. (Source: Birth Defects Research Part A: Clinical and Molecular Teratology)
Source: Birth Defects Research Part A: Clinical and Molecular Teratology - September 1, 2015 Category: Perinatology & Neonatology Authors: Mingqin Wang, Patrizia De Marco, Elisa Merello, Pierre Drapeau, Valeria Capra, Zoha Kibar Tags: Brief Report Source Type: research

Using the electronic medical record to assess contraception usage among women taking category D or X medications
ConclusionAccording to data obtained from the electronic medical record, women who are taking a category D or X medication are not always asked about sexual activity. Contraception usage among women taking category D or X medications and who were sexually active with men was similar to the general population. Contraception usage should be better in this population given the risk of an unintended pregnancy includes fetal exposure to a potential teratogen. The electronic medical record creates an opportunity for an intervention to increase contraception utilization in this population. Birth Defects Research (Part A), 2015. ...
Source: Birth Defects Research Part A: Clinical and Molecular Teratology - August 25, 2015 Category: Perinatology & Neonatology Authors: Sheila K Mody, John Paul Farala, Jennifer Wu, Robert Felix, Christina Chambers Tags: Brief Report Source Type: research

Association of maternal homocysteine and vitamins status with the risk of neural tube defects in Tunisia: A case–control study
ConclusionLower concentrations of folate and vitamin B12 are related to the increased risk of NTDs. Both folate and vitamin B12 intake insufficiency could contribute to the increased risk of NTDs. A dietary supplement, combining folate and vitamin B12, might be an effective measure to decrease the NTDs incidence in Tunisia. Birth Defects Research (Part A), 2015. © 2015 Wiley Periodicals, Inc. (Source: Birth Defects Research Part A: Clinical and Molecular Teratology)
Source: Birth Defects Research Part A: Clinical and Molecular Teratology - August 17, 2015 Category: Perinatology & Neonatology Authors: Kaouther Nasri, Mohamed Kacem Ben Fradj, Asma Touati, Mariem Aloui, Nadia Ben Jemaa, Aida Masmoudi, Michèle Véronique Elmay, Souhail Omar, Moncef Feki, Naziha Kaabechi, Raja Marrakchi, Soumeya Siala Gaigi Tags: Original Research Article Source Type: research

Issue Information
(Source: Birth Defects Research Part A: Clinical and Molecular Teratology)
Source: Birth Defects Research Part A: Clinical and Molecular Teratology - August 14, 2015 Category: Perinatology & Neonatology Tags: Issue Information Source Type: research

Polymorphisms in maternal folate pathway genes interact with arsenic in drinking water to influence risk of myelomeningocele
CONCLUSIONOur results support the hypothesis that environmental arsenic exposure increases the risk of myelomeningocele by means of interaction with folate metabolic pathways. Birth Defects Research (Part A), 2015. © 2015 Wiley Periodicals, Inc. (Source: Birth Defects Research Part A: Clinical and Molecular Teratology)
Source: Birth Defects Research Part A: Clinical and Molecular Teratology - August 6, 2015 Category: Perinatology & Neonatology Authors: Maitreyi Mazumdar, Linda Valeri, Ema G. Rodrigues, Md Omar Sharif Ibne Hasan, Rezina Hamid, Ligi Paul, Jacob Selhub, Fareesa Silva, Md Golam Mostofa, Quazi Quamruzzaman, Mahmuder Rahman, David C. Christiani Tags: Original Research Article Source Type: research

Racial disparities in heterotaxy syndrome
ConclusionThis study represents one of the largest population‐based studies of HTX to date, with a novel finding of higher rates of HTX among Hispanic infants of mostly Mexican origin, as well as among female infants of only non‐Hispanic white and black mothers. These findings warrant further investigation.Birth Defects Research (Part A), 2015. © 2015 Wiley Periodicals, Inc. (Source: Birth Defects Research Part A: Clinical and Molecular Teratology)
Source: Birth Defects Research Part A: Clinical and Molecular Teratology - August 1, 2015 Category: Perinatology & Neonatology Authors: Keila N. Lopez, Lisa K. Marengo, Mark A. Canfield, John W. Belmont, Heather A. Dickerson Tags: Original Research Article Source Type: research

Parental risk factors for oral clefts among Central Africans, Southeast Asians, and Central Americans
ConclusionOur study represents one of the first international studies investigating risk factors for clefts among multiethnic underserved populations. Our findings suggest a multifactorial etiology including both maternal and paternal factors. Birth Defects Research (Part A), 2015. © 2015 The Authors Birth Defects Research Part A: Clinical and Molecular Teratology Published by Wiley Periodicals, Inc. (Source: Birth Defects Research Part A: Clinical and Molecular Teratology)
Source: Birth Defects Research Part A: Clinical and Molecular Teratology - August 1, 2015 Category: Perinatology & Neonatology Authors: Jane C. Figueiredo, Stephanie Ly, Kathleen S. Magee, Ugonna Ihenacho, James W. Baurley, Pedro A. Sanchez‐Lara, Frederick Brindopke, Thi‐Hai‐Duc Nguyen, Viet Nguyen, Maria Irene Tangco, Melissa Giron, Tamlin Abrahams, Grace Jang, Annie Vu, Emily Zolf Tags: Original Research Article Source Type: research

Novel evidence of association with nonsyndromic cleft lip with or without cleft palate was shown for single nucleotide polymorphisms in FOXF2 gene in an Asian population
CONCLUSIONOur results provided statistical evidence of linkage and association between FOXF2 and nonsyndromic cleft lip with or without cleft palate. Birth Defects Research (Part A), 2015. © 2015 Wiley Periodicals, Inc. (Source: Birth Defects Research Part A: Clinical and Molecular Teratology)
Source: Birth Defects Research Part A: Clinical and Molecular Teratology - August 1, 2015 Category: Perinatology & Neonatology Authors: Lingxue Bu, Qianqian Chen, Hong Wang, Tianxiao Zhang, Jacqueline B. Hetmanski, Holger Schwender, Margaret Parker, Yah‐Huei Wu Chou, Vincent Yeow, Samuel S. Chong, Bo Zhang, Ethylin Wang Jabs, Alan F. Scott, Terri H. Beaty Tags: Original Research Article Source Type: research

Issue Information
(Source: Birth Defects Research Part A: Clinical and Molecular Teratology)
Source: Birth Defects Research Part A: Clinical and Molecular Teratology - July 20, 2015 Category: Perinatology & Neonatology Tags: Issue Information Source Type: research

Twin reversed arterial perfusion sequence is more common than generally accepted
ConclusionEarly acardiac twinning is not a rare event. The 1944‐based 1% acardiac monochorionic incidence has a weak basis and could therefore be (much) larger. Knowing this incidence more precisely may contribute to our knowledge of embryonic splitting in unequal cell masses. Birth Defects Research (Part A), 2015. © 2015 Wiley Periodicals, Inc. (Source: Birth Defects Research Part A: Clinical and Molecular Teratology)
Source: Birth Defects Research Part A: Clinical and Molecular Teratology - July 14, 2015 Category: Perinatology & Neonatology Authors: Martin J.C. Gemert, Jeroen P.H.M. Wijngaard, Frank P.H.A. Vandenbussche Tags: Brief Report Source Type: research

Factors associated with inpatient hospitalizations among patients aged 1 to 64 years with Congenital heart defects, Arkansas 2006 to 2011
ConclusionIndividuals with CHDs in Arkansas experience variation in hospital use and costs by patient characteristics. Future research should investigate factors associated with readmissions, cardiac procedures, and comorbidities, as these are strongly associated with hospital costs. Birth Defects Research (Part A), 2015. © 2015 Wiley Periodicals, Inc. (Source: Birth Defects Research Part A: Clinical and Molecular Teratology)
Source: Birth Defects Research Part A: Clinical and Molecular Teratology - July 14, 2015 Category: Perinatology & Neonatology Authors: Regina M. Simeone, Matthew E. Oster, Charlotte A. Hobbs, James M. Robbins, R. Thomas Collins, Margaret A. Honein Tags: Original Research Article Source Type: research