Birth Defects Research Part A: Clinical and Molecular Teratology This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

Issue Information
(Source: Birth Defects Research Part A: Clinical and Molecular Teratology)
Source: Birth Defects Research Part A: Clinical and Molecular Teratology - April 14, 2015 Category: Perinatology & Neonatology Tags: Issue Information Source Type: research

Residential radon and birth defects: A population‐based assessment
ConclusionIn the first study of residential radon and birth defects, we found associations with cleft lip w/wo cleft palate and cystic hygroma / lymphangioma. Other associations were suggested. The ecological nature of this study and multiple comparisons suggest that our results be interpreted with caution. Birth Defects Research (Part A), 2015. © 2015 Wiley Periodicals, Inc. (Source: Birth Defects Research Part A: Clinical and Molecular Teratology)
Source: Birth Defects Research Part A: Clinical and Molecular Teratology - April 6, 2015 Category: Perinatology & Neonatology Authors: Peter H. Langlois, MinJae Lee, Philip J. Lupo, Mohammad H. Rahbar, Ruben K. Cortez Tags: Original Research Article Source Type: research

Next steps for birth defects research and prevention: The birth defects study to evaluate pregnancy exposures (BD‐STEPS)
ConclusionThe goal of BD‐STEPS is to provide women and healthcare providers with information they need to make decisions to promote the healthiest pregnancy possible. Birth Defects Research (Part A), 2015. © 2015 Wiley Periodicals, Inc. (Source: Birth Defects Research Part A: Clinical and Molecular Teratology)
Source: Birth Defects Research Part A: Clinical and Molecular Teratology - April 6, 2015 Category: Perinatology & Neonatology Authors: Sarah C. Tinker, Suzan L. Carmichael, Marlene Anderka, Marilyn L. Browne, Kristin M. Caspers Conway, Robert E. Meyer, Wendy N. Nembhard, Richard S. Olney, Jennita Reefhuis, Tags: Original Article Source Type: research

Is drug insurance status an effect modifier in epidemiologic database studies? The case of maternal asthma and major congenital malformations
ConclusionThe increased risk of major congenital malformation associated with asthma was significantly higher among pregnant women publicly insured with social welfare than among those privately insured. As a result of this effect modification by drug insurance status, findings from Québec observational studies using databases mainly formed of patients publicly insured with social welfare may not be generalized to the entire population. Birth Defects Research (Part A), 2015. © 2015 Wiley Periodicals, Inc. (Source: Birth Defects Research Part A: Clinical and Molecular Teratology)
Source: Birth Defects Research Part A: Clinical and Molecular Teratology - April 6, 2015 Category: Perinatology & Neonatology Authors: Lucie Blais, Fatima‐Zohra Kettani, Amélie Forget, Marie‐France Beauchesne, Catherine Lemière Tags: Original Article Source Type: research

Gastroschisis and young mothers: What makes them different from other mothers of the same age?
ConclusionA previous pregnancy loss was identified as the main risk factor for gastroschisis, while an increased use of sex hormones, perhaps related to the previous loss, could trigger a disruptive mechanism, due to their thrombophilic effect. Birth Defects Research (Part A), 2015. © 2015 Wiley Periodicals, Inc. (Source: Birth Defects Research Part A: Clinical and Molecular Teratology)
Source: Birth Defects Research Part A: Clinical and Molecular Teratology - April 6, 2015 Category: Perinatology & Neonatology Authors: Monica Rittler, Hebe Campaña, Monica L. Ermini, Juan A. Gili, Fernando A. Poletta, Mariela S. Pawluk, Lucas G. Giménez, Viviana R. Cosentino, Eduardo E. Castilla, Jorge S López‐Camelo Tags: Original Research Article Source Type: research

Maternal exposures in the National Birth Defects Prevention Study: Time trends of selected exposures
ConclusionLong‐term, population‐based case–control studies continue to be an effective way to assess exposure‐birth defects associations and provide guidance to health care providers. However, investigators examining rare outcomes covering many years of data collection need to be cognizant of time trends in exposures. Birth Defects Research (Part A), 2015. © 2015 Wiley Periodicals, Inc. (Source: Birth Defects Research Part A: Clinical and Molecular Teratology)
Source: Birth Defects Research Part A: Clinical and Molecular Teratology - April 1, 2015 Category: Perinatology & Neonatology Authors: April L. Dawson, Hilda Razzaghi, Annelise Arth, Mark A. Canfield, Samantha E. Parker, Jennita Reefhuis, Tags: Original Research Article Source Type: research

Maternal occupational exposure to ionizing radiation and major structural birth defects
ConclusionWe assessed 39 birth defects, observing that maternal occupations with potential exposure to IR were associated with a significantly increased risk for 4 birth defects and a significantly protected risk for 1 birth defect. These results should be interpreted cautiously because our measurement of exposure is qualitative, some of these associations may be due to occupational exposures that are correlated with IR and some may be due to chance. However, these findings serve as the first evaluation of these relationships in a large study and may be useful for generating hypotheses for future studies. Birth Defects Res...
Source: Birth Defects Research Part A: Clinical and Molecular Teratology - March 28, 2015 Category: Perinatology & Neonatology Authors: Hyeyeun Lim, A.J. Agopian, Lawrence W. Whitehead, Charles W. Beasley, Peter H. Langlois, Robert J. Emery, Dorothy Kim Waller, Tags: Original Research Article Source Type: research

Plasma folate levels in early to mid pregnancy after a nation‐wide folic acid supplementation program in areas with high and low prevalence of neural tube defects in china
CONCLUSIONPlasma folate levels among pregnant Chinese women increased dramatically after the nation‐wide folic acid supplementation program in both rural and urban areas, and in populations of high and low NTD prevalence. The nation‐wide program should have a component to ensure that supplementation begins before pregnancy. Birth Defects Research (Part A), 2015. © 2015 Wiley Periodicals, Inc. (Source: Birth Defects Research Part A: Clinical and Molecular Teratology)
Source: Birth Defects Research Part A: Clinical and Molecular Teratology - March 24, 2015 Category: Perinatology & Neonatology Authors: Jufen Liu, Lili Gao, Yali Zhang, Lei Jin, Zhiwen Li, Le Zhang, Qinqin Meng, Rongwei Ye, Linlin Wang, Aiguo Ren Tags: Original Research Article Source Type: research

rs1801133C>T polymorphism in MTHFR is a risk factor for nonsyndromic cleft lip with or without cleft palate in the Brazilian population
ConclusionOur findings provide evidences for the involvement of rs1801133 in the development of NSCL/P in the Brazilian population. Birth Defects Research (Part A), 2015. © 2015 Wiley Periodicals, Inc. (Source: Birth Defects Research Part A: Clinical and Molecular Teratology)
Source: Birth Defects Research Part A: Clinical and Molecular Teratology - March 24, 2015 Category: Perinatology & Neonatology Authors: Pamella Kelly Farias de Aguiar, Ricardo D. Coletta, Allane Maria Lacerda Ferreira de Oliveira, Renato Assis Machado, Paulo Germano Cavalcante Furtado, Lindalva Alves de Oliveira, Sibele Nascimento de Aquino, Hercilio Martelli‐Junior, Silvia Regina de Al Tags: Original Research Article Source Type: research

Placenta previa and risk of major congenital malformations among singleton births in Finland
CONCLUSIONUsing a large population‐based study, we found that placenta previa was weakly, but significantly associated with an increased risk of major congenital malformations in singleton births. Future studies should examine the association between placenta previa and individual types of congenital malformations, specifically in high‐risk pregnancies. Birth Defects Research (Part A), 2015. © 2015 Wiley Periodicals, Inc. (Source: Birth Defects Research Part A: Clinical and Molecular Teratology)
Source: Birth Defects Research Part A: Clinical and Molecular Teratology - March 24, 2015 Category: Perinatology & Neonatology Authors: Vijaya Kancherla, Sari Räisänen, Mika Gissler, Michael R. Kramer, Seppo Heinonen Tags: Original Research Article Source Type: research

Risk of cancer among children with birth defects: A novel approach
ConclusionThis novel approach aimed to prevent inflated HRs arising from reverse causation, and allow identification of associations beyond those already well documented. Larger studies using this method are needed to explore currently undocumented associations between BDs and cancers. Birth Defects Research (Part A), 2015. © 2015 Wiley Periodicals, Inc. (Source: Birth Defects Research Part A: Clinical and Molecular Teratology)
Source: Birth Defects Research Part A: Clinical and Molecular Teratology - March 24, 2015 Category: Perinatology & Neonatology Authors: Somer Dawson, Adrian K. Charles, Carol Bower, Nicholas H. de Klerk, Elizabeth Milne Tags: Original Research Article Source Type: research

Y‐craniosynostosis by premature fusion of the metopic and coronal sutures: A new nosological entity or a variety of Saethre‐Chotzen syndrome?
ConclusionThis case further illustrates the variability of the clinical spectrum of craniofacial disorders associated with TWIST1 abnormalities. It is important to note that the Saethre‐Chotzen syndrome caused by microdeletion is generally characterized by a mental disability. However, of interest, the postoperative psychomotor development of the child considered hereby was within the normal limits. Birth Defects Research (Part A), 2015. © 2015 Wiley Periodicals, Inc. (Source: Birth Defects Research Part A: Clinical and Molecular Teratology)
Source: Birth Defects Research Part A: Clinical and Molecular Teratology - March 24, 2015 Category: Perinatology & Neonatology Authors: Federico di Rocco, Alexandra Benoit, Jacqueline Vigneron, Pascale Bach Segura, Olivier Klein, Corinne Collet, Eric Arnaud Tags: Brief Report Source Type: research

Issue Information
(Source: Birth Defects Research Part A: Clinical and Molecular Teratology)
Source: Birth Defects Research Part A: Clinical and Molecular Teratology - March 20, 2015 Category: Perinatology & Neonatology Tags: Issue Information Source Type: research

Topiramate use during pregnancy and major congenital malformations in multiple populations
ConclusionTo evaluate a large number of MCMs across many pregnancies, we used crude methods for detecting potential signals. Therefore, these results should be seen as potential signals, not causal. Birth Defects Research (Part A), 2015. © 2015 Wiley Periodicals, Inc. (Source: Birth Defects Research Part A: Clinical and Molecular Teratology)
Source: Birth Defects Research Part A: Clinical and Molecular Teratology - March 16, 2015 Category: Perinatology & Neonatology Authors: Patricia Tennis, K. Arnold Chan, Suellen M. Curkendall, De‐Kun Li, Daniel Mines, Craig Peterson, Elizabeth B. Andrews, Brian Calingaert, Hong Y. Chen, Gaurav Deshpande, Nicholas Everage, Crystal N. Holick, Nicole M. Meyer, Ella T. Nkhoma, Sherry Quinn, Tags: Original Research Article Source Type: research

A genome‐wide study of inherited deletions identified two regions associated with nonsyndromic isolated oral clefts
ConclusionsThese genes or nearby regulatory elements may be involved in the etiology of oral clefts. Birth Defects Research (Part A), 2015. © 2015 Wiley Periodicals, Inc. (Source: Birth Defects Research Part A: Clinical and Molecular Teratology)
Source: Birth Defects Research Part A: Clinical and Molecular Teratology - March 16, 2015 Category: Perinatology & Neonatology Authors: Samuel G. Younkin, Robert B. Scharpf, Holger Schwender, Margaret M. Parker, Alan F. Scott, Mary L. Marazita, Terri H. Beaty, Ingo Ruczinski Tags: Original Research Article Source Type: research