Birth Defects Research Part A: Clinical and Molecular Teratology Birth Defects Research Part A: Clinical and Molecular Teratology RSS feedThis is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

Age range for inclusion affects ascertainment by birth defects registers
ConclusionThis study highlights the value of birth defect registers collecting information about birth defects from terminations of pregnancy, stillbirths, and live births up to a child's fifth birthday. Reviewing diagnosis date provides insight into the pattern of diagnosis of different birth defects. This provides valuable information to medical specialists and researchers regarding the interpretation of information from birth defect data collections. Birth Defects Research (Part A), 2016. © 2016 Wiley Periodicals, Inc. (Source: Birth Defects Research Part A: Clinical and Molecular Teratology)
Source: Birth Defects Research Part A: Clinical and Molecular Teratology - June 20, 2016 Category: Perinatology & Neonatology Authors: Catherine S. Gibson, Heather Scott, Eric Haan, Wendy Scheil Tags: Original Research Article Source Type: research

Abstracts from the 13th EUROCAT SCIENTIFIC SYMPOSIUM: Advancing congenital anomaly research through collaboration, 16–17 June 2016, Milan, Italy
(Source: Birth Defects Research Part A: Clinical and Molecular Teratology)
Source: Birth Defects Research Part A: Clinical and Molecular Teratology - June 13, 2016 Category: Perinatology & Neonatology Tags: Abstracts from the 13th EUROCAT SCIENTIFIC SYMPOSIUM Source Type: research

Use of azathioprine and corticosteroids during pregnancy and birth outcome in women diagnosed with inflammatory bowel disease
ConclusionUse of azathioprine and corticosteroids was often reduced or discontinued before or during early pregnancy followed by an increased use of corticosteroids later in pregnancy. Women diagnosed with IBD and with prescriptions for azathioprine and/or corticosteroids, have an increased risk of LBW, pre‐term birth, and SGA. Birth Defects Research (Part A) 106:494–499, 2016. © 2016 Wiley Periodicals, Inc. (Source: Birth Defects Research Part A: Clinical and Molecular Teratology)
Source: Birth Defects Research Part A: Clinical and Molecular Teratology - June 13, 2016 Category: Perinatology & Neonatology Authors: Anne Veie Plauborg, Anne Vinkel Hansen, Ester Garne Tags: Research Article Source Type: research

Absence of prenatal ultrasound surveillance: Data from the Portuguese congenital anomalies registry
ConclusionFor pregnant women who did not receive an ultrasound screening examination during pregnancy, the strongest statistically associated factors were professional occupation, ethnicity, and number of miscarriages in previous gestations. Birth Defects Research (Part A) 106:489–493, 2016. © 2016 Wiley Periodicals, Inc. (Source: Birth Defects Research Part A: Clinical and Molecular Teratology)
Source: Birth Defects Research Part A: Clinical and Molecular Teratology - June 13, 2016 Category: Perinatology & Neonatology Authors: Sandrina Correia, Ausenda Machado, Paula Braz, Ana Paula Rodrigues, Carlos Matias‐Dias Tags: Research Article Source Type: research

Use of hierarchical models to analyze European trends in congenital anomaly prevalence
ConclusionThere were no substantial differences between independent analyses of each subgroup and hierarchical models when using the EUROCAT anomaly subgroups. Considering each anomaly separately, therefore, remains an appropriate method for the detection of potential changes in prevalence by surveillance systems. Hierarchical models do, however, remain an interesting alternative method of analysis when considering the risks of specific exposures in relation to the prevalence of congenital anomalies, which could be investigated in other studies. Birth Defects Research (Part A) 106:480–10, 2016. © 2016 Wiley Periodicals,...
Source: Birth Defects Research Part A: Clinical and Molecular Teratology - June 13, 2016 Category: Perinatology & Neonatology Authors: Alana Cavadino, David Prieto‐Merino, Marie‐Claude Addor, Larraitz Arriola, Fabrizio Bianchi, Elizabeth Draper, Ester Garne, Ruth Greenlees, Martin Haeusler, Babak Khoshnood, Jenny Kurinczuk, Bob McDonnell, Vera Nelen, Mary O'Mahony, Hanitra Randrianai Tags: Research Article Source Type: research

Evidence for a teratogenic risk in the offspring of health personnel exposed to ionizing radiation?!
ConclusionPrevious explorative findings were corroborated by this feasibility study. The increased prevalence for CA could not be explained by any other factor. A preferable prospective active design is achievable, and the participation rate is essential to calculate valid results and answer this important issue. Birth Defects Research (Part A) 106:475–479, 2016. © 2016 Wiley Periodicals, Inc. (Source: Birth Defects Research Part A: Clinical and Molecular Teratology)
Source: Birth Defects Research Part A: Clinical and Molecular Teratology - June 13, 2016 Category: Perinatology & Neonatology Authors: Awi Wiesel, Gabriela Stolz, Annette Queisser‐Wahrendorf Tags: Research Article Source Type: research

Management and outcomes of neonates with down syndrome admitted to neonatal units
ConclusionNeonates with Down syndrome are more likely than unaffected neonates to be admitted to a neonatal unit, have a prolonged stay, and be discharged home on supplemental oxygen. Birth Defects Research (Part A) 106:468–474, 2016. © 2016 Wiley Periodicals, Inc. (Source: Birth Defects Research Part A: Clinical and Molecular Teratology)
Source: Birth Defects Research Part A: Clinical and Molecular Teratology - June 13, 2016 Category: Perinatology & Neonatology Authors: Jake P. Mann, Eugene Statnikov, Neena Modi, Nik Johnson, Anna Springett, Joan K. Morris Tags: Research Article Source Type: research

Is advanced maternal age a risk factor for congenital heart disease?
ConclusionWe found little evidence that advanced maternal age is a risk factor for CHD. There is no evidence that women in the United Kingdom should be referred for specialist prenatal cardiac screening based on their age. Birth Defects Research (Part A) 106:461–467, 2016. © 2016 Wiley Periodicals, Inc. (Source: Birth Defects Research Part A: Clinical and Molecular Teratology)
Source: Birth Defects Research Part A: Clinical and Molecular Teratology - June 13, 2016 Category: Perinatology & Neonatology Authors: Kate E. Best, Judith Rankin Tags: Research Article Source Type: research

Issue Information
(Source: Birth Defects Research Part A: Clinical and Molecular Teratology)
Source: Birth Defects Research Part A: Clinical and Molecular Teratology - June 13, 2016 Category: Perinatology & Neonatology Tags: Issue Information Source Type: research

Cover Image
(Source: Birth Defects Research Part A: Clinical and Molecular Teratology)
Source: Birth Defects Research Part A: Clinical and Molecular Teratology - June 13, 2016 Category: Perinatology & Neonatology Tags: Cover Image Source Type: research

Prenatal diagnosis, hospital characteristics, and mortality in transposition of the great arteries
ConclusionLower CSC TGA patient volume was associated with higher neonatal mortality. Prenatal diagnosis may improve survival in lower volume CSCs. Birth Defects Research (Part A), 2016. © 2016 Wiley Periodicals, Inc. (Source: Birth Defects Research Part A: Clinical and Molecular Teratology)
Source: Birth Defects Research Part A: Clinical and Molecular Teratology - June 13, 2016 Category: Perinatology & Neonatology Authors: Diego A. Lara, David E. Fixler, Mary K. Ethen, Mark A. Canfield, Wendy N. Nembhard, Shaine A. Morris Tags: Original Research Article Source Type: research

Obituary: Dr. Ed Lammer
(Source: Birth Defects Research Part A: Clinical and Molecular Teratology)
Source: Birth Defects Research Part A: Clinical and Molecular Teratology - May 31, 2016 Category: Perinatology & Neonatology Authors: Richard H. Finnell, Gary M. Shaw Tags: Obituary Source Type: research

In utero exposure to venlafaxine, a serotonin–norepinephrine reuptake inhibitor, increases cardiac anomalies and alters placental and heart serotonin signaling in the rat
ConclusionIn utero venlafaxine exposure altered the placental index and induced fetal cardiac anomalies in rats. We propose that the increased incidence of cardiac anomalies is mediated through alterations in serotonin signaling in the placenta and fetal heart. Birth Defects Research (Part A), 2016. © 2016 Wiley Periodicals, Inc. (Source: Birth Defects Research Part A: Clinical and Molecular Teratology)
Source: Birth Defects Research Part A: Clinical and Molecular Teratology - May 31, 2016 Category: Perinatology & Neonatology Authors: Laetitia Laurent, Chunwei Huang, Sheila R. Ernest, Anick Berard, Cathy Vaillancourt, Barbara F. Hales Tags: Original Research Article Source Type: research

A novel 2q14.1q14.3 deletion involving GLI2 and RNU4ATAC genes associated with partial corpus callosum agenesis and severe intrauterine growth retardation
ConclusionThis case emphasizes the variable expressivity of the 2q14 microdeletion and reinforces the hypothesis that agenesis of corpus callosum, microcephaly, developmental delay, and distinctive craniofacial features may be part of the phenotypic spectrum characterizing the affected patients. We suggest that GLI2 is a dosage‐sensitive gene that may be responsible for the agenesis of corpus callosum observed in the proband. Birth Defects Research (Part A), 2016. © 2016 Wiley Periodicals, Inc. (Source: Birth Defects Research Part A: Clinical and Molecular Teratology)
Source: Birth Defects Research Part A: Clinical and Molecular Teratology - May 31, 2016 Category: Perinatology & Neonatology Authors: Carole Goumy, Mathilde Gay‐Bellile, Gaelle Salaun, Stephan Kemeny, Eleonore Eymard‐Pierre, Marie Biard, Celine Pebrel‐Richard, Philippe Vanlieferinghen, Christine Francannet, Andrei Tchirkov, Helene Laurichesse, Charles Rouzade, Laetitia Gouas, Phil Tags: Brief Report Source Type: research

Inositol, neural tube closure and the prevention of neural tube defects
Susceptibility to neural tube defects (NTDs), such as anencephaly and spina bifida is influenced by genetic and environmental factors including maternal nutrition. Maternal periconceptional supplementation with folic acid significantly reduces the risk of an NTD‐affected pregnancy, but does not prevent all NTDs, and “folic acid non‐responsive” NTDs continue to occur. Similarly, among mouse models of NTDs, some are responsive to folic acid but others are not. Among nutritional factors, inositol deficiency causes cranial NTDs in mice while supplemental inositol prevents spinal and cranial NTDs in the curly tail (Grhl...
Source: Birth Defects Research Part A: Clinical and Molecular Teratology - May 31, 2016 Category: Perinatology & Neonatology Authors: Nicholas D.E. Greene, Kit‐Yi Leung, Andrew J. Copp Tags: Research Article Source Type: research