High doses of alcohol during pregnancy cause DNA damages in osteoblasts of newborns rats

ConclusionOur results showed that prenatal exposure to ethanol induced DNA damage in osteoblasts, as shown by micronucleus formation and higher percentage of DNA in the comet tail. It can be concluded that prenatal exposure to ethanol damages osteoblast DNA in newborns exposed to high doses of ethanol during pregnancy, suggesting that prenatal ethanol consumption has a direct effect on fetal osteoblasts. Birth Defects Research (Part A), 2015. © 2015 Wiley Periodicals, Inc.

Source: Birth Defects Research Part A: Clinical and Molecular Teratology - December 21, 2015 Category: Perinatology & Neonatology Authors: Isabel Chaves Silva Carvalho, Tamires Pereira Dutra, Dennia Perez De Andrade, Ivan Balducci, Cristina Pacheco‐Soares, Rosilene Fernandes da Rocha Tags: Original Research Article Source Type: research