The Antiplatelet Effect of Clopidogrel Decreases With Patient Age
In conclusion, the antiplatelet effect of clopidogrel decreases with patient age. (Source: Angiology)
Source: Angiology - October 6, 2016 Category: Cardiology Authors: Xhelili, E., Eichelberger, B., Kopp, C. W., Koppensteiner, R., Panzer, S., Gremmel, T. Tags: Antiplatelet Drugs Source Type: research

Cardiac Trauma
Cardiac trauma is a leading cause of death in the United States and occurs mostly due to motor vehicle accidents. Blunt cardiac trauma and penetrating chest injuries are most common, and both can lead to aortic injuries. Timely diagnosis and early management are the key to improve mortality. Cardiac computed tomography and cardiac ultrasound are the 2 most important diagnostic modalities. Mortality related to cardiac trauma remains high despite improvement in diagnosis and management. (Source: Angiology)
Source: Angiology - October 6, 2016 Category: Cardiology Authors: Gosavi, S., Tyroch, A. H., Mukherjee, D. Tags: Review Source Type: research

Copeptin for All: A Biomarker From Infant Pathology to Adult Cardiovascular Disease
(Source: Angiology)
Source: Angiology - October 6, 2016 Category: Cardiology Authors: Paraskevas, K. I., Briana, D. D., Malamitsi-Puchner, A. Tags: Editorials Source Type: research

Editorial: Scoring and Other Assessments of Plaque Morphology and Pathology
(Source: Angiology)
Source: Angiology - October 6, 2016 Category: Cardiology Authors: Whayne, T. F. Tags: Editorials Source Type: research

Full Blood Count as a Potential Predicting Factor of Contrast-Induced Nephropathy After Endovascular Aortic Aneurysm Repair
(Source: Angiology)
Source: Angiology - September 15, 2016 Category: Cardiology Authors: Spanos, K., Matsagkas, M., Giannoukas, A. D. Tags: Letter to the Editor Source Type: research

Carbondioxide-Aided Angiography Decreases Contrast Volume and Preserves Kidney Function in Peripheral Vascular Interventions
Chronic kidney disease is a common comorbidity in patients with peripheral artery disease. We investigated the safety and efficacy of carbon dioxide (CO2) as supplemental contrast agent to decrease contrast volume during fluoroscopy-guided peripheral vascular procedures in routine angiological practice. We analyzed 191 consecutive interventions of the lower extremity in claudicants and critical limb ischemia (CLI) that were performed with iodinated contrast media (ICM) alone (n = 154) or with the aided or exclusive use of CO2 (n = 37). The technical success rate, total irradiation, and intervention time were not significan...
Source: Angiology - September 15, 2016 Category: Cardiology Authors: Stegemann, E., Tegtmeier, C., Bimpong-Buta, N. Y., Sansone, R., Uhlenbruch, M., Richter, A., Stegemann, B., Roden, M., Westenfeld, R., Kelm, M., Heiss, C. Tags: Peripheral Artery Disease Source Type: research

Plasma Levels of Inflammatory Biomarkers in Peripheral Arterial Disease: Results of a Cohort Study
The objective of this study was to investigate the plasma levels of inflammatory markers in patients with PAD and in healthy controls. The following plasma levels of biomarkers were measured in 80 patients with PAD (mean age 68 ± 5 years) and in 72 healthy participants (mean age 67 ± 6 years): interleukin 6 (IL-6), tumor necrosis factor α (TNF-α), L-selectin (LS), neopterin (N), P-selectin (PS), E-selectin (ES), vascular cell adhesion molecule 1 (VCAM-1), intercellular adhesion molecule 1 (ICAM-1), and matrix metalloproteinase 2 (MMP-2), and 9 (MMP-9). Significantly higher levels of IL-6 (P < ....
Source: Angiology - September 15, 2016 Category: Cardiology Authors: Signorelli, S. S., Anzaldi, M., Libra, M., Navolanic, P. M., Malaponte, G., Mangano, K., Quattrocchi, C., Di Marco, R., Fiore, V., Neri, S. Tags: Peripheral Artery Disease Source Type: research

Low Rates of Revascularization and High In-Hospital Mortality in Patients With Ischemic Lower Limb Amputation: Morbidity and Mortality of Ischemic Amputation
Conclusion: The total number of ischemic LLA and amputation-related in-hospital mortality remains high in Germany in the 21st century. The poor outcome of patients with CLI might in part be due to underuse of revascularizations prior to amputation. (Source: Angiology)
Source: Angiology - September 15, 2016 Category: Cardiology Authors: Malyar, N. M., Freisinger, E., Meyborg, M., Lüders, F., Fürstenberg, T., Kröger, K., Torsello, G., Reinecke, H. Tags: Lower Limb Amputation Source Type: research

Predictive Value for Galectin 3 and Cardiotrophin 1 in Hemodialysis Patients
Patients with end-stage renal disease (ESRD) have an increased risk of all-cause mortality. The prognostic value of the new cardiac biomarkers, cardiotrophin 1 (CT-1) and galectin 3 (GAL-3), has not yet been defined in hemodialysis (HD) patients. The aim of this study was to determine the use of these novel biomarkers for predicting mortality in HD patients. Plasma GAL-3 and CT-1 concentrations were determined (at baseline) in 88 HD patients followed for 22.2 ± 4.7 months. During the follow-up period, 21 (23.9%) deaths were recorded. According to Cox analysis, the cutoff point for GAL-3 as a predictor of mortality w...
Source: Angiology - September 15, 2016 Category: Cardiology Authors: Hogas, S., Schiller, A., Voroneanu, L., Constantinescu, D., Timar, R., Cianga, P., Siriopol, D., Bob, F., Cianga, C., Onofriescu, M., Gadalean, F., Hogas, M., Mihaescu, A., Bilha, S. C., Timar, B., Kanbay, M., Banach, M., Covic, A. Tags: Hemodialysis Source Type: research

Human Endothelial Cell-Specific Molecule-1 (Endocan) and Coronary Artery Disease and Microvascular Angina
In conclusion, endocan could be a common predictor of the endothelium-dependent inflammatory processes, rather than related with specific risk factors. (Source: Angiology)
Source: Angiology - September 15, 2016 Category: Cardiology Authors: Cimen, T., Efe, T. H., Akyel, A., Sunman, H., Algül, E., Sahan, H. F., Erden, G., Özdemir, S., Alay, E. F., Dogan, M., Yeter, E. Tags: Coronary Artery Disease Source Type: research

CHA2DS2-VASc Score is a Predictor of No-Reflow in Patients With ST-Segment Elevation Myocardial Infarction Who Underwent Primary Percutaneous Intervention
In conclusion, CHA2DS2-VASc score is associated with higher risk of no-reflow and in-hospital mortality rates in patients who underwent primary PCI. (Source: Angiology)
Source: Angiology - September 15, 2016 Category: Cardiology Authors: Ipek, G., Onuk, T., Karatas, M. B., Gungor, B., Osken, A., Keskin, M., Oz, A., Tanik, O., Hayiroglu, M. I., Yaka, H. Y., Ozturk, R., Bolca, O. Tags: Coronary Artery Disease Source Type: research

Liver Function is Associated With Response to Clopidogrel Therapy in Patients Undergoing Angioplasty and Stenting
In conclusion, liver function is associated with response to clopidogrel therapy in patients undergoing angioplasty and stenting for cardiovascular disease. (Source: Angiology)
Source: Angiology - September 15, 2016 Category: Cardiology Authors: Gremmel, T., Mueller, M., Koppensteiner, R., Panzer, S. Tags: Coronary Artery Disease Source Type: research

Relationship of Endothelial Cell-Specific Molecule 1 Level in Stress Hyperglycemia Patients With Acute ST-Segment Elevation Myocardial Infarction: A Pilot Study
Endothelial cell–specific molecule 1 ([ESM-1], endocan) is a new biomarker of endothelial dysfunction, which may be involved in the pathogenesis of atherosclerosis and stress hyperglycemia in patients with acute ST-segment elevation myocardial infarction (STEMI). Therefore, we investigated serum ESM-1 levels in patients with stress hyperglycemia having STEMI; 105 patients with STEMI and 33 individuals as a control group were included in the study. The patients were followed up for 3 months and major adverse cardiac events (MACEs) were recorded. Serum ESM-1 level was significantly higher in patients with stress hyperg...
Source: Angiology - September 15, 2016 Category: Cardiology Authors: Qiu, C., Sui, J., Zhang, Q., Wei, P., Wang, P., Fu, Q. Tags: Coronary Artery Disease Source Type: research

Validation of the Ability of SYNTAX and Clinical SYNTAX Scores to Predict Adverse Cardiovascular Events After Stent Implantation: A Systematic Review and Meta-Analysis
To compare the predicative ability of SYNTAX (Synergy between PCI with Taxus and Cardiac Surgery) and clinical SYNTAX scores for major adverse cardiac events (MACEs) after stent implantation in patients with coronary artery disease (CAD). Studies were identified by electronic and manual searches. Twenty-six studies were included in the meta-analysis. The pooled C-statistics of SYNTAX score for 1- and 5-year all-cause mortality (ACM) were 0.65 (95% confidence interval [CI]: 0.61-0.68) and 0.62 (95% CI: 0.59-0.65), respectively, with weak heterogeneity. The 1- and 5-year ACM pooled C-statistics for clinical SYNTAX scores wer...
Source: Angiology - September 15, 2016 Category: Cardiology Authors: Chen, J., Tang, B., Lin, Y., Ru, Y., Wu, M., Wang, X., Chen, Q., Chen, Y., Wang, J. Tags: Coronary Artery Disease Source Type: research

Gender Disparity in the Safety and Efficacy of Radial and Femoral Access for Coronary Intervention: A Systematic Review and Meta-Analysis
In conclusion, TRI may improve the safety and efficacy of outcomes in both sexes and be an effective means to cut down the gender difference in prognosis. (Source: Angiology)
Source: Angiology - September 15, 2016 Category: Cardiology Authors: Huang, F.-Y., Huang, B.-T., Wang, P.-J., Zhang, C., Zuo, Z.-L., Liao, Y.-B., Xia, T.-L., Gui, Y.-Y., Peng, Y., Liu, W., Chen, M., Zhu, Y. Tags: Reviews Source Type: research