Thrombolysis May Reduce the Incidence/Extent of Postprocedural Ischemic Strokes Associated With Carotid Artery Stenting: A Hypothesis
(Source: Angiology)
Source: Angiology - July 24, 2015 Category: Cardiology Authors: Paraskevas, K. I., Veith, F. J. Tags: Editorials Source Type: research

Nonalcoholic Fatty Liver Disease, Cardiovascular Risk, and Carotid Inflammation
(Source: Angiology)
Source: Angiology - July 24, 2015 Category: Cardiology Authors: Al-Rasadi, K., Rizzo, M., Montalto, G., Berg, G. Tags: Editorials Source Type: research

Coronary Collateral Circulation and Cardiovascular Risk Factors: Is There a Paradox?
We sought to determine the association of major cardiovascular risk factors and other comorbidities with the presence or absence of coronary collateral (CC) circulation. All electronic medical records from 2010 to 2011 were retrospectively reviewed. A total of 563 patients were divided into 2 groups: CC present (180) and CC absent (383). Smoking (P = .012, odds ratio [OR] 1.58), hypercholesterolemia (P = .001, OR 2.21), and hypertension (P = .034, OR 1.75) were associated with the presence of CC. Increasing body mass index (BMI, P = .001) and decreasing estimated glomerular filtration rate (eGFR, P = .042) were associated ...
Source: Angiology - June 15, 2015 Category: Cardiology Authors: Bhatt, H., Kochar, S., Htun, W. W., Julliard, K., Fernaine, G. Tags: Cardiovascular Risk Factors Source Type: research

Reduced Protein C Activity Might be Associated With Progression of Peripheral Arterial Disease
We evaluated the effect of reduced activities of protein C (PC) and protein S (PS) on the progression of peripheral arterial disease (PAD). We measured PC and PS activities in 106 patients with PAD and 44 patients with abdominal aortic aneurysm (AAA) in the same period. The incidences of PC deficiency in PAD and AAA were 4.7% and 4.5%, respectively, and those of PS were 14.1% and 11.4%, respectively; these incidences were much higher than those in the normal population. The PC and PS activities were significantly lower in patients having critical limb ischemia (CLI) than in patients with intermittent claudication. In parti...
Source: Angiology - June 15, 2015 Category: Cardiology Authors: Komai, H., Shindo, S., Sato, M., Ogino, H. Tags: Peripheral Arterial Disease Source Type: research

Characteristics of Patients With Diabetes Having Normal Coronary Arteries
We evaluated the association between risk variables in diabetic patients with normal and diseased coronary arteries in a retrospective cohort study conducted at Rashid Hospital, Dubai. A total of 4446 patients underwent coronary angiography due to various indications; 43% had type 2 diabetes mellitus (T2DM). Among the diabetic patients, 94% had diseased coronary arteries and the remaining 6% had absolutely normal arteries. The normal coronary group had significantly lower low-density lipoprotein cholesterol (LDL-C) and a higher high-density lipoprotein cholesterol (HDL-C) levels than the diseased group. Patients with norma...
Source: Angiology - June 15, 2015 Category: Cardiology Authors: Binbrek, A. S., Ali, S. M., Baslaib, F. O., Ali, A. A. S. Tags: Diabetes Source Type: research

Validation of High-Resolution Ultrasound Measurements of Intima-Media Thickness of the Radial Artery for the Assessment of Structural Remodeling
Radial artery (RA) intima–media thickness (IMT) could be used to study short- and long-term structural vascular adaptation following transradial cardiac catheterization. We aimed at assessing the reliability and reproducibility of RA-IMT measurement. Using high-resolution ultrasound, we studied RA-IMT in 17 patients, who underwent transradial catheterization via the right RA 1 to 12 months before. Radial artery intima–media thickness was measured in both arms, with the left RA as control. Repeated measurements were performed by 2 examiners and offline analyses were performed by independent blinded interpreters....
Source: Angiology - June 15, 2015 Category: Cardiology Authors: Stegemann, E., Sansone, R., Stegemann, B., Kelm, M., Heiss, C. Tags: Vascular Ultrasound Source Type: research

The Effect of Residing Altitude on Levels of High-Density Lipoprotein Cholesterol: A Pilot Study From the Omani Arab Population
Lower mortality rates from coronary heart disease and higher levels of serum high-density lipoprotein cholesterol (HDL-C) have been observed in populations residing at high altitude. However, this effect has not been investigated in Arab populations, which exhibit considerable genetic homogeneity. We assessed the relationship between residing altitude and HDL-C in 2 genetically similar Omani Arab populations residing at different altitudes. The association between the levels of HDL-C and other metabolic parameters was also investigated. The levels of HDL-C were significantly higher in the high-altitude group compared with ...
Source: Angiology - June 15, 2015 Category: Cardiology Authors: Al Riyami, N. B., Banerjee, Y., Al-Waili, K., Rizvi, S. G., Al-Yahyaee, S., Hassan, M. O., Albarwani, S., Al-Rasadi, K., Bayoumi, R. A. Tags: Lipids Source Type: research

Acute Effects of Intracoronary Tirofiban on No-Reflow Phenomena in Patients With ST-Segment Elevated Myocardial Infarction Undergoing Primary Percutaneous Coronary Intervention
We evaluated the acute effect of intracoronary administration of tirofiban on no-reflow phenomenon in patients with ST-segment elevated myocardial infarction undergoing primary percutaneous coronary intervention. Consecutive patients (n = 162) were randomized into 2 groups based on whether intracoronary tirofiban was administered. After the administration of intracoronary tirofiban, thrombolysis in myocardial infarction (TIMI) flow grade significantly increased (P < .001) and successful reperfusion was achieved in 26 (32%) patients. In the placebo group, however, after the administration of intracoronary placebo the TIM...
Source: Angiology - June 15, 2015 Category: Cardiology Authors: Akpek, M., Sahin, O., Sarli, B., Baktir, A. O., Saglam, H., Urkmez, S., Ergin, A., Oguzhan, A., Arinc, H., Kaya, M. G. Tags: Coronary Heart Diseases Source Type: research

Predictors of Chronic Total Occlusion in Nonculprit Artery in Patients With Acute Coronary Syndrome: Mean Platelet Volume and Uric Acid
Chronic total occlusion (CTO) in a noninfarct-related artery (non-IRA) is an independent predictor of mortality in acute coronary syndrome (ACS). Mean platelet volume (MPV) and serum uric acid (SUA) are associated with cardiovascular events in ACS. We investigated the relationship between the presence of non-IRA-CTO with MPV and SUA levels in patients with ACS. Patients (n = 1024) who underwent urgent coronary angiography for ACS were included in this study. Blood samples were drawn on admission. Patients were categorized into 2 groups: non-IRA-CTO (–) and non-IRA-CTO (+). The MPV and SUA levels on admission were sig...
Source: Angiology - June 15, 2015 Category: Cardiology Authors: Kurtul, A., Yarlioglues, M., Murat, S. N., Celik, I. E., Demircelik, M. B., Ocek, A. H., Duran, M., Ergun, G., Cetin, M., Ornek, E. Tags: Coronary Heart Diseases Source Type: research

Neutrophil to Lymphocyte Ratio is Related to Stent Thrombosis and High Mortality in Patients With Acute Myocardial Infarction
We investigated whether the neutrophil to lymphocyte ratio (NLR) can predict stent thrombosis (STh) and high mortality rate in patients with ST-segment elevation myocardial infarction (STEMI). We analyzed data of 102 patients with STh and 450 patients with STEMI admitted to 2 high volume hospitals. Preprocedural NLR was significantly higher in patients with STh (P < .001). There was a significantly higher mortality rate in patients with high NLR during hospitalization (P < .001). Also, in the STh group there was a significantly higher mortality rate in patients with high NLR (P < .001). In receiver–operating...
Source: Angiology - June 15, 2015 Category: Cardiology Authors: Ayca, B., Akın, F., Celik, O., Sahin, I., Yildiz, S. S., Avci, I. I., Gulsen, K., Okuyan, E., Dinckal, M. H. Tags: Coronary Heart Diseases Source Type: research

Chronic Venous Disease and Comorbidities
We report the relations between comorbidities and chronic venous disease. In this cross-sectional study, information was gathered from 1679 Serbian patients. The majority (65.0%) of patients were women. Mild forms of chronic venous disease (clinical, etiologic, anatomic and pathophysiologic [CEAP] classification; C0s-C1) were more frequent in women (11.6%), while severe forms (CEAP C4-C6) were more commonly encountered in men (42.1%). The most frequent comorbidity was emphysema/chronic obstructive pulmonary disease in both groups (74.3% in males and 70.6% in females). For females, diabetes mellitus (P < .005), arterial ...
Source: Angiology - June 15, 2015 Category: Cardiology Authors: Matic, P., Jolic, S., Tanaskovic, S., Soldatovic, I., Katsiki, N., Isenovic, E., Radak, D. Tags: Venous Disease Source Type: research

Noninvasive Transcutaneous Monitoring in Long-Term Follow-Up of Patients With Thromboangiitis Obliterans Treated With Intravenous Iloprost
We evaluated the effectiveness of intravenous iloprost (IVI) in outpatients with thromboangiitis obliterans (TAO) and lower limb noninvasive transcutaneous monitoring (TCM) at follow-up (FU). Ten consecutive patients with TAO underwent IVI therapy. Transcutaneous oxygen (TcPo 2) and carbon dioxide (TcPco 2) determination and laser Doppler flowmetry (LDF) were performed before and after IVI at 3, 6, and 12 months of FU. Clinical response was positive in 7 patients, whereas 3 nonresponders underwent a second IVI cycle with 1 showing a late positive clinical response. After 12 months of FU, all...
Source: Angiology - June 15, 2015 Category: Cardiology Authors: Melillo, E., Grigoratos, C., Sanctis, F. D., Spontoni, P., Nuti, M., Dell'Omodarme, M., Ferrari, M., Balbarini, A. Tags: Thromboangiitis Obliterans Source Type: research

Atrial Fibrillation Is Associated With Increased Mean Platelet Volume and Apnea Hypopnea Index in Patients With Obstructive Sleep Apnea
This study investigated whether there is a relationship between atrial fibrillation (AF), mean platelet volume (MPV), and apnea hypopnea index (AHI) in patients who have obstructive sleep apnea syndrome (OSAS). We enrolled patients who had OSAS with either AF or normal sinus rhythm (NSR). We divided 90 patients (aged 50-80 years) into 2 groups: group 1 consisted of 40 patients with OSAS having AF and group 2 of 50 patients with OSAS having NSR. Mean platelet volume was higher in patients with AF than in those with NSR (9.8 ± 0.6 vs 8.4 ± 0.6 fL; P < .001). The MPV and AHI were substantial variables associa...
Source: Angiology - June 15, 2015 Category: Cardiology Authors: Akyuz, A., Akkoyun, D. C., Değirmenci, H., Alp, R. Tags: Sleep Apnea Source Type: research

Association Between Contrast Media Volume-Glomerular Filtration Rate Ratio and Contrast-Induced Acute Kidney Injury After Primary Percutaneous Coronary Intervention
In conclusion, CV–e-GFR ratio is significantly associated with CI-AKI after pPCI. (Source: Angiology)
Source: Angiology - June 15, 2015 Category: Cardiology Authors: Celik, O., Ozturk, D., Akin, F., Ayca, B., Yalcın, A. A., Erturk, M., Bıyık, I., Ayaz, A., Akturk, I. F., Enhos, A., Aslan, S. Tags: Contrast-induced Nephropathy Source Type: research

Long-Term Follow-Up of Patients at High Risk for Nephropathy After Contrast Exposure
Contrast medium-induced acute kidney injury (CI-AKI) is associated with morbidity and mortality, but the long-term outcomes of patients who do not develop CI-AKI remain unknown. We assessed clinical end points during long-term follow-up in patients at high risk for nephropathy who did not develop CI-AKI. Patients (n = 135) with impaired renal function (estimated glomerular filtration rate: 30-60 mL/min/1.73 m2) were divided into 2 groups according to contrast media (CM) exposure. The primary end point of this study was a composite outcome measure of death or renal failure requiring dialysis. Multivariate analyses identifie...
Source: Angiology - June 15, 2015 Category: Cardiology Authors: Abaci, O., Harmankaya, O., Kocas, B., Kocas, C., Bostan, C., Coskun, U., Yildiz, A., Ersanli, M. Tags: Contrast-induced Nephropathy Source Type: research