Effect of Cilostazol Following Endovascular Intervention for Peripheral Artery Disease
Efficacy of endovascular therapy (EVT) with nitinol stents for femoropopliteal (FP) lesions is limited by restenosis. Oral cilostazol reduces angiographic restenosis rate; however, treatment duration remains unclear. In a retrospective analysis of a multicenter database of 3471 consecutive limbs in 2737 patients (mean age: 72 ± 9 years; 61% diabetic; and 26% on regular dialysis) undergoing EVT for FP lesions between January 2004 and December 2011, we compared Kaplan-Meier estimated primary patency after EVT followed or not by cilostazol treatment. We used Cox hazard regression analysis to assess temporal association...
Source: Angiology - August 12, 2015 Category: Cardiology Authors: Nanto, K., Iida, O., Takahara, M., Soga, Y., Suzuki, K., Hirano, K., Kawasaki, D., Shintani, Y., Suematsu, N., Yamaoka, T., Uematsu, M. Tags: Peripheral Artery Disease Source Type: research
Comparison of Serum Cystatin C and Creatinine Level Changes for Prognosis of Patients After Peripheral Arterial Angiography
We compared changes in serum cystatin C (Cys C) and creatinine (sCr) levels for detecting contrast-induced acute kidney injury; 350 consecutive patients who underwent peripheral arterial angiography were prospectively enrolled. Serum Cys C and sCr levels were assayed at predefined time points after contrast-media exposure. During 1-year follow-up, major adverse events (MAEs) including all-cause mortality and dialysis were assessed. A sCr increase ≥25% was not associated with MAEs, whereas a serum Cys C increase ≥5% at 24 hours was associated with higher probability of MAEs (P = .010). The independent predictors of 1-...
Source: Angiology - August 12, 2015 Category: Cardiology Authors: Yang, Y., Zhao, X., Tang, X., Lu, J., Zhou, M., Wang, W., Wang, L., Guo, D., Ding, F. Tags: Peripheral Artery Disease Source Type: research
Is Arterial Hypertension Control Enough to Improve Aortic Stiffness in Untreated Patients With Hypertension? A 3-Year Follow-Up Study
Aortic stiffness is an important determinant of cardiovascular risk. We studied the long-term influence of successful antihypertensive treatment after a 3-year follow-up, regarding aortic stiffness improvement from baseline evaluation in never treated middle-aged patients with mild to moderate essential hypertension. In 132 patients with hypertension, aortic stiffness was evaluated by carotid–femoral artery pulse wave velocity (PWV). Patients with 24-hour mean systolic and diastolic blood pressure ≤130/80 mm Hg after treatment at reevaluation were considered as well controlled. The PWV after treatment was signific...
Source: Angiology - August 12, 2015 Category: Cardiology Authors: Triantafyllidi, H., Trivilou, P., Ikonomidis, I., Kontsas, K., Tzortzis, S., Pavlidis, G., Lekakis, J. Tags: Hypertension Source Type: research
Relationship Between Alcohol Consumption and Serum Lipid Profiles Among Middle-Aged Population in China: A Multiple-Center Cardiovascular Epidemiological Study
We assessed the relationship between alcohol consumption and serum lipids in a middle-aged Chinese population. The overall prevalence of drinking among 10 154 participants was 34.07% in males and 3.61% in females. Heavy alcohol drinkers (≥ 30 g/d) tended to be older, smokers, hypertensive, do heavy physical activity, and have a lower body mass index. Levels of high-density lipoprotein cholesterol (HDL-C), apolipoprotein (apo) A1, low-density lipoprotein cholesterol–HDL-C ratio, and apo B–apo A1 ratio rose with increase in alcohol intake in males. An increase of 0.27 mmol/L in triglycerides and a decrease of ...
Source: Angiology - August 12, 2015 Category: Cardiology Authors: Hao, G., Wang, Z., Zhang, L., Chen, Z., Wang, X., Guo, M., Tian, Y., Shao, L., Zhu, M. Tags: Lipids Source Type: research
One-Year Outcomes of Emergency Department Patients With Atrial Fibrillation: A Prospective, Multicenter Registry in China
There is lack of data about patient characteristics, practice patterns, and long-term adverse outcomes in patients with atrial fibrillation (AF) attending emergency departments (EDs) in China. A total of 2016 patients from 20 representative EDs were included. During 1 year, all-cause mortality was 291 (14.6%) cases, stroke/noncentral nervous system systemic embolism rate was 159 (8.0%) cases, and major bleeding was 26 (1.3%) cases. Heart failure, the major cause of mortality, accounted for 43.0% of deaths. Of 375 (18.6%) patients who used warfarin at baseline, only 217 (57.9%) patients were still on anticoagulation therapy...
Source: Angiology - August 12, 2015 Category: Cardiology Authors: Yang, Y.-M., Shao, X.-H., Zhu, J., Zhang, H., Liu, Y., Gao, X., Yu, L.-T., Liu, L.-S., Zhao, L., Yu, P.-F., Zhang, H., He, Q., Gu, X.-D. Tags: Atrial Fibrillation Source Type: research
Congestive Heart Failure With Apparently Preserved Left Ventricular Systolic Function: A 10-Year Observational Study
We analyzed the clinical presentation and outcomes (from 2003 to 2013) of heart failure (HF) with apparently normal systolic function (HFPEF). Based on the echocardiographic left ventricular ejection fraction (LVEF), patients were divided into 2 groups, group 1 (<50%) and group 2 (≥50%). Of 2212 patients with HF, 20% were in group 2. Patients in group 2 were more likely to be older, females, Arabs, hypertensive, and obese (P = .001). Patients in group 1 were mostly Asians and had more troponin-T positivity (P = .001). Inhospital cardiac arrest, shock, and deaths were significantly greater in group 1. On multivariate ...
Source: Angiology - August 12, 2015 Category: Cardiology Authors: El-Menyar, A., Shabana, A., Arabi, A., Al-Thani, H., Asaad, N., AlBinALi, H., Singh, R., Gomaa, M., Gehani, A. Tags: Heart Failure Source Type: research
Impact of Serum Albumin Levels on Contrast-Induced Acute Kidney Injury in Patients With Acute Coronary Syndromes Treated With Percutaneous Coronary Intervention
Patients with acute coronary syndromes (ACSs) undergoing percutaneous coronary intervention (PCI) are at high risk of contrast-induced acute kidney injury (CI-AKI), a complication associated with poor clinical outcomes. Serum albumin (SA) levels are associated with cardiovascular mortality. We assessed the association between SA levels and the risk of CI-AKI in patients with ACS (n = 890) treated with PCI. Patients were divided into 2 groups: patients with and without CI-AKI. Contrast-induced acute kidney injury was defined as an increase in serum creatinine (≥25% or ≥0.5 mg/dL) from baseline occurring 72 hours after...
Source: Angiology - August 12, 2015 Category: Cardiology Authors: Murat, S. N., Kurtul, A., Yarlioglues, M. Tags: Coronary Artery Disease Source Type: research
Serum Endocan Level and the Severity of Coronary Artery Disease: A Pilot Study
Endothelial-specific molecule 1 (endocan) is expressed in endothelial cells. We investigated the relationship between acute coronary syndrome (ACS) and serum endocan levels. We included 30 individuals as a control group and 53 patients diagnosed with ACS. The severity of coronary artery disease was assessed by a modified Gensini stenosis and SYNTAX scoring system. There was a significant difference in serum endocan levels between the control group and the ACS group (0.75 ± 0.13 vs 0.86 ± 0.25 ng/mL, P = .014). There was also a significant difference in serum endocan levels between diabetic patients with ACS a...
Source: Angiology - August 12, 2015 Category: Cardiology Authors: Kose, M., Emet, S., Akpinar, T. S., Kocaaga, M., Cakmak, R., Akarsu, M., Yuruyen, G., Arman, Y., Tukek, T. Tags: Coronary Artery Disease Source Type: research
Hyperuricemia Is an Independent Predictor of Contrast-Induced Acute Kidney Injury and Mortality in Patients Undergoing Percutaneous Coronary Intervention
We investigated whether hyperuricemia is an independent predictor of contrast-induced acute kidney injury (CI-AKI) and mortality in patients undergoing percutaneous coronary intervention (PCI). In a single-center study of 1772 patients undergoing PCI, the development of CI-AKI and mortality during a 2.8-year median follow-up period was assessed. The incidence of CI-AKI was significantly higher in the hyperuricemic group than in the normouricemic group (5.78% vs 1.76%, P < .001). According to multivariate analysis (after adjusting for potential confounding factors), hyperuricemia predicted CI-AKI (odds ratio: 1.962; 95% ...
Source: Angiology - August 12, 2015 Category: Cardiology Authors: Guo, W., Liu, Y., Chen, J.-Y., Chen, S.-Q., Li, H.-L., Duan, C.-Y., Liu, Y.-H., Tan, N. Tags: Coronary Artery Disease Source Type: research
Usefulness of the Logistic Clinical Syntax Score in Prediction of Saphenous Vein Graft Failure in Patients Undergoing Coronary Artery Bypass Grafting
We investigated the association between the preoperative logistic clinical syntax score (log CSS), saphenous vein graft (SVG) patency, and major adverse cardiac and cerebrovascular events (MACCEs) after coronary artery bypass surgery (CABG). Of 1875 patients undergoing isolated CABG between 2009 and 2011, 267 patients, who later underwent coronary angiography, were included in the study. The primary end point was at least 1 graft occlusion on the follow-up coronary angiogram. The secondary end point was a composite of MACCE. In multivariate analysis, log CSS was found as a strong predictor of SVG failure (odds ratio [OR] 0...
Source: Angiology - August 12, 2015 Category: Cardiology Authors: Ozturk, D., Celık, O., Cakmak, H. A., Akın, F., Aslan, S., Enhos, A., Tasbulak, O., Ayca, B., Erkanlı, K., Bakır, I. Tags: Coronary Artery Disease Source Type: research
Predictive Value of the Logistic Clinical SYNTAX Score
(Source: Angiology)
Source: Angiology - August 12, 2015 Category: Cardiology Authors: Nibber, A., Ziada, K. M., Whayne, T. F. Tags: Editorials Source Type: research
Peripheral Arterial Disease and Cardiovascular Risk: The Role of Mediterranean Diet
(Source: Angiology)
Source: Angiology - August 12, 2015 Category: Cardiology Authors: Chrysohoou, C., Esposito, K., Giugliano, D., Panagiotakos, D. B. Tags: Editorials Source Type: research
The Role of Statins in Preventing Contrast-Induced Acute Kidney Injury: A Narrative Review
In conclusion, it is uncertain whether statins should be prescribed to prevent CI-AKI in the absence of other indications. (Source: Angiology)
Source: Angiology - August 12, 2015 Category: Cardiology Authors: Akyuz, S., Yaylak, B., Altay, S., Kasikcioglu, H., Cam, N. Tags: Review Source Type: research
Neutrophil-Lymphocyte Ratio in Behcet Disease
(Source: Angiology)
Source: Angiology - July 24, 2015 Category: Cardiology Authors: Ozturk, C., Balta, S., Balta, I., Celik, T. Tags: Response Letter Source Type: research
The Relation Between Neutrophil-Lymphocyte Ratio and Endothelial Dysfunction
(Source: Angiology)
Source: Angiology - July 24, 2015 Category: Cardiology Authors: Unlu, M., Arslan, Z. Tags: Letter Source Type: research
