Contrast-Induced Nephropathy: An "All or None" Phenomenon?
Contrast-induced nephropathy (CIN) represents an important adverse effect of contrast media (CM) administration. Contrast-induced nephropathy is associated with prolonged hospitalization as well as increased cardiovascular morbidity, renal morbidity, and all-cause mortality. Several risk factors may predict CIN incidence, and various scores and ratios have been proposed to identify high-risk patients. Novel biomarkers may provide an earlier diagnosis of CIN. A multifactorial approach is required for CIN prevention including hydration, administration of low- or iso-osmolar CM, minimizing CM volume, and statin administration...
Source: Angiology - June 15, 2015 Category: Cardiology Authors: Katsiki, N., Athyros, V. G., Karagiannis, A., Mikhailidis, D. P. Tags: Reviews Source Type: research
High-Sensitivity C-Reactive Protein and Statin Initiation
The assessment of cardiovascular risk and treatment of cardiovascular diseases are major public health issues worldwide. Inflammation is now recognized as a key regulatory process that links multiple risk factors for atherosclerosis. The substantial number of patients having cardiovascular events lack commonly established risk factors. The utility of high-sensitivity C-reactive protein (hsCRP), a circulating biomarker related to inflammation, may provide additional information in risk prediction. This review will consider the impact of hsCRP level on initiation of statin therapy. (Source: Angiology)
Source: Angiology - June 15, 2015 Category: Cardiology Authors: Trpkovic, A., Stanimirovic, J., Rizzo, M., Resanovic, I., Soskic, S., Jevremovic, D., Isenovic, E. R. Tags: Reviews Source Type: research
Obstructive Sleep Apnea and Atrial Fibrillation: Do They Synergistically Increase Cardiovascular Risk?
(Source: Angiology)
Source: Angiology - June 15, 2015 Category: Cardiology Authors: Steiropoulos, P., Papanas, N. Tags: Editorial Source Type: research
Reply From the Author: Diabetes Mellitus and Depression in Hispanic Patients
(Source: Angiology)
Source: Angiology - April 15, 2015 Category: Cardiology Authors: Mukherjee, D., Azimova, K. Tags: With Response Letter Source Type: research
Glucose Levels May Predict Depression in Patients With Cardiovascular Diseases
(Source: Angiology)
Source: Angiology - April 15, 2015 Category: Cardiology Authors: Yilmaz, S., Kuyumcu, M. S., Kuyumcu, A., Aydoğdu, S. Tags: Letter Source Type: research
Endocan and Atherosclerosis
(Source: Angiology)
Source: Angiology - April 15, 2015 Category: Cardiology Authors: Balta, S., Mikhailidis, D. P., Demirkol, S., Celik, T., Ozturk, C., Iyisoy, A. Tags: Response Letter Source Type: research
Endocan and Endothelial Dysfunction
(Source: Angiology)
Source: Angiology - April 15, 2015 Category: Cardiology Authors: Aparci, M., Isilak, Z., Uz, O., Yalcin, M., Kucuk, U. Tags: Letter Source Type: research
Correlation of Carotid Artery Disease Severity and Vasomotor Response of Cerebral Blood Vessels
We assessed reactivity of cerebral vessels on hypercapnia in patients with carotid occlusive disease. The effects of vascular risk factors on carotid atherosclerosis and vasomotor reactivity (VMR) of cerebral arterioles were also examined. Patients (n = 50) with carotid stenosis (≥30% in 1 or both sides) were included; 30 patients acted as controls. Hypertension, hyperlipidemia, diabetes, cardiac diseases, inflammation, and smoking were recorded. Vasomotor reactivity was assessed with the apnea test by transcranial Doppler ultrasonography and estimated by flow velocity changes in the middle cerebral artery before and af...
Source: Angiology - April 15, 2015 Category: Cardiology Authors: Krdžić, I., Čovičković-Šternić, N., Katsiki, N., Isenović, E. R., Radak, Đorđe Tags: Carotid Artery Diseases Source Type: research
Association Between Nonalcoholic Fatty Liver Disease and Carotid Artery Inflammation Evaluated by 18F-Fluorodeoxyglucose Positron Emission Tomography
We assessed the association between nonalcoholic fatty liver disease (NAFLD) and carotid artery inflammation measured by 18F-fluorodeoxyglucose (FDG) positron emission tomography/computed tomography. Participants were 755 consecutive otherwise healthy adult males who underwent a general health screening program. Carotid FDG uptake, represented as maximum target-to-background ratio, was increased with mild (n = 237; 1.61 ± 0.14; P = .033) and moderate NAFLD (n = 145; 1.63 ± 0.16; P = .005) compared with controls (n = 373; 1.58 ± 0.15). In patients aged >50 years, moderate NAFLD was the only independe...
Source: Angiology - April 15, 2015 Category: Cardiology Authors: Moon, S. H., Noh, T. S., Cho, Y. S., Hong, S. P., Hyun, S. H., Choi, J. Y., Kim, B.-T., Lee, K.-H. Tags: Carotid Artery Diseases Source Type: research
Management and 1-Year Outcomes of Patients With Atrial Fibrillation in the Middle East: Gulf Survey of Atrial Fibrillation Events
We describe management and outcomes of patients with nonvalvular atrial fibrillation (AF) in the Middle East. Consecutive patients with AF presenting to emergency departments (EDs) were prospectively enrolled. Among 1721 patients with nonvalvular AF, mean age was 59 ± 16 years and 44% were women. Comorbidities were common such as hypertension (59%), diabetes (33%), and coronary artery disease (33%). Warfarin was not prescribed to 40% of patients with Congestive heart failure, Hypertension, Age, Diabetes mellitus, Stroke/TIA2 score of ≥2. One-year rates of stroke/transient ischemic attack (TIA) and all-cause morta...
Source: Angiology - April 15, 2015 Category: Cardiology Authors: Zubaid, M., Rashed, W. A., Alsheikh-Ali, A. A., Al-Zakwani, I., AlMahmeed, W., Shehab, A., Sulaiman, K., Qudaimi, A. A., Asaad, N., Amin, H., on behalf of the Gulf Survey of Atrial Fibrillation Events (Gulf SAFE) Investigators Tags: Atrial Fibrillation Source Type: research
Mean Platelet Volume on Admission Improves Risk Prediction in Patients With Acute Coronary Syndromes
In conclusion, the inclusion of MPV into the GRACE risk score could allow improved risk classification, thereby refining risk stratification of patients with ACS. (Source: Angiology)
Source: Angiology - April 15, 2015 Category: Cardiology Authors: Niu, X., Yang, C., Zhang, Y., Zhang, H., Yao, Y. Tags: Coronary Heart Diseases Source Type: research
A Comparison of Transradial and Transfemoral Approaches for Percutaneous Coronary Intervention in Elderly Patients Based on a Propensity Score Analysis
In conclusion, TRA showed better safety in elderly patients; it should be considered as a preferred route for elderly patients. (Source: Angiology)
Source: Angiology - April 15, 2015 Category: Cardiology Authors: He, P.-Y., Yang, Y.-J., Qiao, S.-B., Xu, B., Yao, M., Wu, Y.-J., Yuan, J.-Q., Chen, J., Liu, H.-B., Dai, J., Tang, X.-R., Wang, Y., Li, W., Gao, R.-L. Tags: Coronary Heart Diseases Source Type: research
Neutrophil-Lymphocyte Ratio and Platelet-Lymphocyte Ratio Combination Can Predict Prognosis in Patients With ST-Segment Elevation Myocardial Infarction Undergoing Primary Percutaneous Coronary Intervention
We assessed the effect of combination of neutrophil–lymphocyte ratio (NLR) and platelet–lymphocyte ratio (PLR) in predicting in-hospital and long-term mortality in patients (n = 2518) undergoing primary percutaneous coronary intervention (pPCI). Cutoff values for NLR and PLR were calculated with receiver–operating characteristic (ROC) curves. If both PLR and NLR were above the threshold, patients were classified as "high risk." If either PLR or NLR was above the threshold individually, patients were classified as "intermediate risk." High-risk (n = 693) and intermediate-risk (n = 545) groups had higher in...
Source: Angiology - April 15, 2015 Category: Cardiology Authors: Cicek, G., Acıkgoz, S. K., Bozbay, M., Altay, S., Uğur, M., Uluganyan, M., Uyarel, H. Tags: Coronary Heart Diseases Source Type: research
Red Cell Distribution Width Predicts Contrast-Induced Nephropathy in Patients Undergoing Percutaneous Coronary Intervention for Acute Coronary Syndrome
In conclusion, increased RDW levels are independently associated with a greater risk of CIN in patients undergoing PCI for ACS. (Source: Angiology)
Source: Angiology - April 15, 2015 Category: Cardiology Authors: Kurtul, A., Yarlioglues, M., Murat, S. N., Demircelik, M. B., Acikgoz, S. K., Ergun, G., Duran, M., Cetin, M., Ornek, E. Tags: Coronary Heart Diseases Source Type: research
Association Between MTHFR C677T Polymorphism and Venous Thromboembolism Risk in the Chinese Population: A Meta-Analysis of 24 Case-Controlled Studies
The association between methylenetetrahydrofolate reductase (MTHFR) gene polymorphisms and venous thromboembolism (VTE) risk in the Chinese population has been widely reported, but results were inconsistent and underpowered. To elucidate the variable results, a meta-analysis and systematic review were performed from all case-controlled studies relating MTHFR C677T polymorphism by pooling data on them. We estimated the pooled odds ratio with its 95% confidence intervals to assess this possible association. Finally, a total of 24 studies with 2339 cases and 4048 controls were included in the current meta-analysis. Significan...
Source: Angiology - April 15, 2015 Category: Cardiology Authors: Zhang, P., Gao, X., Zhang, Y., Hu, Y., Ma, H., Wang, W., Wang, H., Zhang, J., Xu, H., Lu, Z. Tags: Thrombosis Source Type: research
