Elevated Homocysteine and the Risk of Contrast-Induced Nephropathy: A Cohort Study
Contrast-induced nephropathy (CIN) is a common complication in patients with impaired kidney function undergoing coronary angiography/angioplasty. We evaluated whether elevated homocysteine (known to be associated with free radical generation and oxidative stress) increases the risk of CIN. Patients (n = 876) with creatinine clearance <60 mL/min undergoing coronary angiography or percutaneous coronary intervention (PCI) were divided into tertiles of homocysteine levels. Contrast-induced nephropathy was defined as ≥0.5 mg/dL or ≥25% creatinine increase 24 to 48 hours post-PCI. A significant relationship was observe...
Source: Angiology - April 9, 2015 Category: Cardiology Authors: Barbieri, L., Verdoia, M., Schaffer, A., Niccoli, G., Perrone-Filardi, P., Bellomo, G., Marino, P., Suryapranata, H., Luca, G. D. Tags: Contrast-Induced Nephropathy Source Type: research
Health-Related Quality of Life in Coronary Heart Disease in Korea: The Korea National Health and Nutrition Examination Survey 2007 to 2011
Using data from 2007 to 2011 of the Korea National Health and Nutrition Examination Survey, we evaluated the influence of coronary heart disease (CHD) on health-related quality of life (HRQoL) as measured by the EQ-5D in comparison with the general population and the predictors of HRQoL in CHD. Compared with the general population, HRQoL was impaired in the EQ-5D dimensions of mobility, usual activities, pain/discomfort, and anxiety/depression. The impairment of HRQoL was much greater in the older age group and in females. In subjects with CHD, the predictors for a low EQ-5D index were old age, female sex, low education, s...
Source: Angiology - April 9, 2015 Category: Cardiology Authors: Lee, H. T., Shin, J., Lim, Y.-H., Kim, K. S., Kim, S. G., Kim, J. H., Lim, H. K. Tags: Coronary Heart Diseases Source Type: research
High Clopidogrel Dose in Patients With Chronic Kidney Disease Having Clopidogrel Resistance After Percutaneous Coronary Intervention
We evaluated the impact of clopidogrel 150 mg/d in patients with chronic kidney disease (CKD) having clopidogrel resistance (CR) after percutaneous coronary intervention (PCI); 1076 consecutive patients with coronary artery disease (CAD) having CKD were enrolled. Maximal platelet aggregation (MPA) was assessed before, 24 hours, and 30 days after a 300-mg loading dose of clopidogrel prior to PCI. After PCI, 370 patients with CR were randomized to receive clopidogrel 75 mg/d (n = 184) or 150 mg/d (n = 186) for 30 days. Stent thrombosis (ST), major adverse cardiac events (MACEs), and bleeding were analyzed after 1 month. Pati...
Source: Angiology - April 9, 2015 Category: Cardiology Authors: Liang, J., Wang, Z., Shi, D., Liu, Y., Zhao, Y., Han, H., Li, Y., Liu, W., Zhang, L., Yang, L., Zhou, Y. Tags: Coronary Heart Diseases Source Type: research
Health Benefits of the Mediterranean Diet: An Update of Research Over the Last 5 Years
The Mediterranean Diet (MedDiet) has been reported to be protective against the occurrence of several diseases. Increasing evidence suggests that the MedDiet could counter diseases associated with chronic inflammation, including metabolic syndrome, atherosclerosis, cancer, diabetes, obesity, pulmonary diseases, and cognition disorders. Adoption of a MedDiet was associated with beneficial effects on the secretion of anti-inflammatory cytokines, antioxidant cellular and circulating biomarkers as well as with regulation of gene polymorphisms involved in the atherosclerotic process. The MedDiet has been considered for the prev...
Source: Angiology - April 9, 2015 Category: Cardiology Authors: Gotsis, E., Anagnostis, P., Mariolis, A., Vlachou, A., Katsiki, N., Karagiannis, A. Tags: Review Source Type: research
Treatment of Diabetic Complications: How Can We Learn by Seeking and Blundering?
(Source: Angiology)
Source: Angiology - April 9, 2015 Category: Cardiology Authors: Pafili, K., Papanas, N., Maltezos, E. Tags: Editorial Source Type: research
