Antianginal Efficacy of Ivabradine in Patients With History of Coronary Revascularization
This study evaluated the antianginal efficacy and effect of ivabradine treatment on quality of life (QOL) in patients with CAD and history of coronary revascularization. This is a post hoc analysis (926 post-revascularization patients) of a prospective, noninterventional study, which included 2403 patients with CAD and stable angina. The data were recorded at baseline, at 1 month and 4 months after inclusion. After ivabradine administration, mean number of anginal events decreased from 2.2 ± 2.3 (median: 2.0, minimum: 0.0, maximum: 21.0, range: 21.0) to 0.3 ± 0.6 (median: 0.0, minimum: 0.0, maximum: 7.0, rang...
Source: Angiology - December 7, 2016 Category: Cardiology Authors: Zarifis, J., Grammatikou, V., Kallistratos, M., Katsivas, A. Tags: Coronary Heart Disease Source Type: research
Scalpels Versus Balloons in Failing Hearts: Case Closed?
(Source: Angiology)
Source: Angiology - December 7, 2016 Category: Cardiology Authors: Richter, D., Vlachopoulos, C., Tousoulis, D. Tags: Editorial Source Type: research
Lowering Heart Rate Post Revascularization: Angina and Quality of Life Improvement
(Source: Angiology)
Source: Angiology - December 7, 2016 Category: Cardiology Authors: Giannoglou, G. D., Giannopoulos, A. A., Chatzizisis, Y. S. Tags: Editorial Source Type: research
Carbon Dioxide Angiography Is a Standard Technique to Supplement Iodinated Contrast Angiography and Can Be a Feasible Alternative
(Source: Angiology)
Source: Angiology - October 6, 2016 Category: Cardiology Authors: Stegemann, E., Sansone, R., Heiss, C. Tags: Response to the Letter Source Type: research
Carbon Dioxide Angiography: To Be or not to Be an Alternative?
(Source: Angiology)
Source: Angiology - October 6, 2016 Category: Cardiology Authors: Dogan, M., Un, H., Aparci, M., Kardesoglu, E. Tags: Letter Source Type: research
Who is Guilty of Subclinical Atherosclerosis in Prediabetes? Chicken or Egg Causality Paradox Between Insulin Resistance and Epicardial Fat: Reply
(Source: Angiology)
Source: Angiology - October 6, 2016 Category: Cardiology Authors: Altin, C., Sade, L. E., Gezmis, E., Muderrisoglu, H. Tags: Response to the Letter Source Type: research
Chicken or Egg Causality Paradox Between Insulin Resistance and Epicardial Fat
(Source: Angiology)
Source: Angiology - October 6, 2016 Category: Cardiology Authors: Canpolat, U., Bahadir, N., Coteli, C. Tags: Letter Source Type: research
Assessment of Subclinical Atherosclerosis by Carotid Intima-Media Thickness and Epicardial Adipose Tissue Thickness in Prediabetes
Impaired fasting glucose (IFG) and impaired glucose intolerance (IGT) are predictors of cardiovascular disease (CVD). We tested the hypothesis that epicardial fat thickness (EFT) and carotid intima–media thickness (cIMT), as markers of early atherosclerosis, are increased in patients with prediabetes. We prospectively enrolled 246 patients (162 with prediabetes and 84 controls). Prediabetes was defined according to American Diabetes Association criteria, and patients were divided into 3 groups: group 1—IFG, group 2—IGT, and group 3—IFG + IGT. Both cIMT and EFT were significantly greater in patients ...
Source: Angiology - October 6, 2016 Category: Cardiology Authors: Altin, C., Sade, L. E., Gezmis, E., Ozen, N., Duzceker, O., Bozbas, H., Eroglu, S., Muderrisoglu, H. Tags: Carotid Artery Disease Source Type: research
Copeptin Levels Do Not Correlate With Cross-Clamping Time in Patients Undergoing Carotid Endarterectomy Under General Anesthesia
In this study, we evaluated copeptin levels in carotid endarterectomy (CEA) patients, perioperatively, to determine whether copeptin levels can be related to carotid artery cross clamping (CC) time and to postoperative neurological outcomes. Copeptin, interleukin 6, C-reactive protein, cortisol, and brain natriuretic peptide were measured preoperatively (T1) and 3 hours postoperatively (T3) as well as intraoperatively (T2). We recruited 77 patients. Values of copeptin rose gradually over the observed times: T1 = 7.9 (6.4-9.6), T2 = 12.6 (9.3-16.8), and T3 = 72.3 (49.1-111.2) pmol/L. There was a significant difference for r...
Source: Angiology - October 6, 2016 Category: Cardiology Authors: Unic-Stojanovic, D., Isenovic, E. R., Jovic, M., Maravic-Stojkovic, V., Miljkovic, M., Gojkovic, T., Milicic, B., Bogdanovic, N., Radak, D. Tags: Carotid Artery Disease Source Type: research
Circulating miR-130a, miR-27b, and miR-210 in Patients With Peripheral Artery Disease and Their Potential Relationship With Oxidative Stress: A Pilot Study
In conclusion, our findings suggest the need for more research to assess if miRs can serve as useful markers for the early diagnosis and monitoring of PAD. (Source: Angiology)
Source: Angiology - October 6, 2016 Category: Cardiology Authors: Signorelli, S. S., Volsi, G. L., Pitruzzella, A., Fiore, V., Mangiafico, M., Vanella, L., Parenti, R., Rizzo, M., Volti, G. L. Tags: Peripheral Artery Disease Source Type: research
Relationship Between the Apolipoprotein E Genotype and LDL Particle Size in Patients With Obstructive Sleep Apnea
Obstructive sleep apnea (OSA) is associated with dyslipidemia and increased cardiovascular risk. We assessed the effects of apolipoprotein E (APOE) genotype on low-density lipoprotein (LDL) and high-density lipoprotein (HDL) particle size and lipid subclasses (separated by gradient gel electrophoresis) in patients with OSA. Stable patients (n = 181) prospectively recruited underwent full polysomnography. Both LDL particle size and LDL I proportion were reduced from 33 homozygotes to 2 carriers and to 4 carriers (analysis of variance: P = .024; P = .040, respectively); carriers of the 4 allele of the APOE genotype had signi...
Source: Angiology - October 6, 2016 Category: Cardiology Authors: Vekic, J., Joppa, P., Habalova, V., Tisko, R., Zeljkovic, A., Pobeha, P., Gojkovic, T., Spasojevic-Kalimanovska, V., Strbova, Z., Kuklisova, Z., Slaba, E., Rizzo, M., Tkacova, R. Tags: Obstructive Sleep Apnea Source Type: research
Plasma Endocan Levels in Patients With Isolated Coronary Artery Ectasia
Endocan is a soluble proteoglycan, secreted by human vascular endothelial cells. Endocan is a marker for vascular pathologies and an important mediator of angiogenesis, strongly associated with inflammation, vascular endothelial dysfunction, and atherosclerosis. The relationship between coronary artery ectasia (CAE) and endocan has not been evaluated. We aimed to investigate this association. Fifty-four patients with isolated CAE without coronary stenosis and 30 controls with normal coronary angiogram were included in this study. Endocan plasma concentrations were measured using an enzyme-linked immunosorbent assay. Patien...
Source: Angiology - October 6, 2016 Category: Cardiology Authors: Turan, T., Akyuz, A. R., Aykan, A. C., Kul, S., Cirakoglu, O. F., Aslan, A. O., Gul, I., Ucar, U., Demir, S., Celik, S. Tags: Coronary Artery Disease Source Type: research
The Association Between {alpha}1-Antitrypsin and Coronary Artery Ectasia
Coronary artery ectasia (CAE) is associated with coronary artery disease (CAD). The underlying pathophysiology of CAE is not fully understood. α1-antitrypsin (A1AT) plays a role in the tissue protease system, and AAT-1 deficiency (A1ATD) has been shown to be related to CAD. We compared A1AT serum levels in patients with and without CAE to determine the association between A1AT levels and the extent of ectasia using the Markis score. We included 50 patients (38 males) with isolated CAE and 46 patients (28 males) with normal coronary arteries after coronary angiography. The levels of A1AT were measured by nephelometry....
Source: Angiology - October 6, 2016 Category: Cardiology Authors: Turhan Caglar, F. N., Ksanski, V., Polat, V., Ungan, I., Kural, A., Ciftci, S., Demir, B., Ugurlucan, M., Akturk, F., Karakaya, O. Tags: Coronary Artery Disease Source Type: research
The Prognostic Value of Percentage Total Plaque Score Adjusted to Age: A Potential Marker of Coronary Vascular Age
Conclusion:
%TPS/Age has incremental prognostic value to traditional risk factors and CCTA measures of CAD and improves evaluation of burden of coronary atherosclerosis and clinical risk. (Source: Angiology)
Source: Angiology - October 6, 2016 Category: Cardiology Authors: Ayoub, C., Yam, Y., Chen, L., Arasaratnam, P., Chow, C. K., Hillis, G. S., Kritharides, L., Chow, B. J. W. Tags: Coronary Artery Disease Source Type: research
Total Bilirubin Levels Predict Subclinical Atherosclerosis in Patients With Prediabetes
Bilirubin may have important antiatherosclerotic effects. Prediabetes (PD), the intermediate stage before diabetes mellitus, is associated with increased cardiovascular morbidity and mortality. We evaluated the relationship between serum bilirubin levels and carotid intima–media thickness (cIMT), as a surrogate marker of subclinical atherosclerosis, in patients with PD. We enrolled 170 consecutive patients with PD. The patients underwent ultrasonography to evaluate cIMT. The patients were divided into groups according to cIMT values (<0.9 vs ≥0.9 mm). The patients with cIMT ≥ 0.9 mm had significantly higher ...
Source: Angiology - October 6, 2016 Category: Cardiology Authors: Hamur, H., Duman, H., Demirtas, L., Bakirci, E. M., Durakoglugil, M. E., Degirmenci, H., Kalkan, K., Yildirim, E., Vuruskan, E. Tags: Subclinical Atherosclerosis Source Type: research
