Trichoepithelioma: A comprehensive review
Trichoepithelioma is an uncommon benign adnexal neoplasm. It can present as a solitary non-familial or multiple familial form. Trichoepithelioma usually develops in early childhood or puberty. Females are more affected. It is attributed to two genetic mutations on chromosomes 9p21 and 16q12-q13. Multiple familial trichoepithelioma is an autosomal-dominant disorder, characterized by numerous nodules and papules, predominantly on the face and occasionally on the scalp, neck, or upper trunk, positive family history, and histopathological findings. The lesions gradually increase in both size and number over time; however, they...
Source: Acta Dermatovenerologica Croatica - July 4, 2018 Category: Dermatology Source Type: research
Bowen ’s disease in dermoscopy
Bowen ’s disease, named after John Templeton Bowen, also known as squamous cell carcinoma in situ is a type of non-melanocytic intraepidermal malignancy. It is estimated that in general population around 3% to 5% of Bowen’s disease transform into invasive squamous cell cancer. Dermoscopy aims in the i dentification of the Bowen’s disease. The most typical dermoscopic features of Bowen’s disease include glomerular vessels and scaly surface. Although dermoscopy of Bowen’s disease has been well established other skin lesions may present similar or identical structures in dermoscpic images le ading to differential ...
Source: Acta Dermatovenerologica Croatica - July 4, 2018 Category: Dermatology Source Type: research
Skin barrier function in primary and secondary Sj ögren’s syndrome patients
Sj ögren’s syndrome (SS) is a systemic autoimmune disease. A large percentage of patients with SS suffer from dry skin, the cause and pathogenesis of which in this group of patients remains obscure. The aim of the present study was to investigate skin barrier function in patients with SS. Measuremen ts of transepidermal water loss (TEWL) and hydration of stratum corneum (corneometry, CM) were performed in 30 female patients with SS (17 with primary SS and 13 with secondary SS), 20 patients with atopic dermatitis (AD) and 14 healthy controls. There were no statistically significant differences i n TEWL values between the...
Source: Acta Dermatovenerologica Croatica - July 4, 2018 Category: Dermatology Source Type: research
Serological diagnosis of syphilis: Preliminary study searching for an algorithm in Turkey
Different algorithms have been proposed to increase the diagnostic capacity of syphilis. We analyzed three common algorithms for detecting suspected syphilis cases in low prevelance Turkish population. The study included a total of 340 clinical serum samples from adults throughout Turkey, who had syphilis as a clinical preliminary diagnosis and were positive on at least one of the following tests: Rapid Plasma Reagin (RPR),Treponema pallidumHaemagglutination test (TPHA) and FTA-abs Ig. In adittion to percent agreement, kappa coefficients were calculated to compare the conformity between the three algorithms. Both the re...
Source: Acta Dermatovenerologica Croatica - July 4, 2018 Category: Dermatology Source Type: research
Quality of life of school and university students with acne
Acne may have severe negative impact on different aspects of patient health-related quality of life (HRQoL). Prevalence of acne in university and school students is high, and the HRQoL of students with acne from different countries was studied.There is a lack of studies on direct comparison of HRQoL impairment of university and school students with acne.The Cardiff Acne Disability Index (CADI) was used to assess the HRQOL in university and school students with self-assessed acne.The CADI results from 159 university and 99 school students with self-reported acne were obtained. Mean age of university and school students was ...
Source: Acta Dermatovenerologica Croatica - July 4, 2018 Category: Dermatology Source Type: research
The value of type IV collagen immunohistochemical staining in the differential diagnosis of autoimmune subepidermal bullous diseases
In conclusion, type IV collagen IHC staining is a simple and useful diagnostic technique for the differential diagnosis of AISBDs. .042) compared with controls. The filiform papillae had partially or completely regenerated in 85.7% of cases in the test group and in 23.1% of the controls (P=0.001). Red patches with raised keratotic rims may have healed spontaneously and reappeared in constantly changing patterns that are typical for MG. This phenomenon was not observed in patients supplemented with zinc, and new atrophy areas occurred in only one case. Low-dose zinc gluconate supplementation may have a positive therapeutic ...
Source: Acta Dermatovenerologica Croatica - July 4, 2018 Category: Dermatology Source Type: research
The effect of zinc gluconate supplementation on the symptoms and tongue epithelium regeneration in non-psoriatic patients with migratory glossitis
The aim of this study was to evaluate zinc gluconate as a treatment option in patients with symptomatic migratory glossitis (MG). Using simple random sampling, 28 non-psoriatic patients with symptomatic MG were divided into a test and control group. The test group took 20 mg/day of chelated zinc gluconate for one month, and was put on a diet rich in zinc. The control group was only put on a diet rich in zinc. Changes in the size of red atrophied areas (width and length) and the intensity of symptoms were evaluated as primary and secondary outcomes, respectively, at baseline, after therapy, and one month later. In the test ...
Source: Acta Dermatovenerologica Croatica - July 4, 2018 Category: Dermatology Source Type: research
Clinical and demographic characteristics of pemphigus vulgaris patients
Pemphigus is an autoimmune disease characterized by intraepithelial bullae and erosions in the skin and mucosa. We aimed to evaluate the clinical and demographic characteristics of pemphigus vulgaris (PV) patients who presented to our Department. Patients who presented to our Department between May 2013 and May 2014, were examined dermatologically and diagnosed with PV based on clinical, histological and direct immunofluorescent findings. Name, family name, and gender of the patients, their complaint at presentation, onset time and location of the lesions, the number of lesions, systemic treatments received by patients and...
Source: Acta Dermatovenerologica Croatica - July 4, 2018 Category: Dermatology Source Type: research
General characteristics and comorbidities in patients with palmoplantar pustulosis
The aim of this prospective study was to analyze comorbidities in patients with palmoplantar pustulosis (PPP). The current study comprised 63 consecutive patients with palmoplantar pustulosis. The control group consisted of 37 patients with psoriasis vulgaris (PSV). The study included a standardized anamnesis, a clinical examination, blood tests for thyroid hormones, as well as calcium, magnesium, antiendomysial antibody, and patch tests. Hypertension was observed in 28/63 (44.44%) patients with PPP. Eight (12.7%) had ischaemic heart disease, and 7/63 (11.11%) had type 2 diabetes mellitus. There was no statistically signif...
Source: Acta Dermatovenerologica Croatica - July 4, 2018 Category: Dermatology Source Type: research
The usage of hypoallergenic cosmetics in patients with atopic dermatitis
The aim of this study was to investigate how many patients with atopic dermatitis applied hypoallergenic cosmetics compared with topical corticosteroids. The study included 41 patients with atopic dermatitis (AD) who were treated from June 1 to July 1, 2017 at the Department of Dermatology and Venerology, Clinical Hospital Mostar. According to the data analyzed, 46.34% of patients used hypoallergenic cosmetics while 24.39% used them periodically. 32.7% patients used topical corticosteroids and 17.07 % used them periodically. 19.51 % of the patients with atopic dermatitis used alternative products, while 17.07% used them pe...
Source: Acta Dermatovenerologica Croatica - July 4, 2018 Category: Dermatology Source Type: research
Evaluation of the importance of immunological profile for pemphigus vulgaris in the light of necessity to modify compensation theory
According to the “desmoglein compensation theory,” anti-Dsg1 and anti-Dsg3 profiles are crucial for the clinical outcome of pemphigus vulgaris. However, recent studies have highlighted several cases with an incompatibility between the antibody profile and clinical manifestation.Data of 37 patients who had been diagnosed pemphigus vulgaris in our Department between January 2014-June 2016 were retrieved from our clinical database. Patients with ABSIS skin involvement scores, oral mucosa extent and severity scores, anti-Dsg1 and Dsg3 antibody profile were included in this retrospective study. Patients with discordance bet...
Source: Acta Dermatovenerologica Croatica - July 4, 2018 Category: Dermatology Source Type: research
Salivary and serum anti-desmoglein 1 and 3 ELISA and indirect immunofluorescence in pemphigus vulgaris: Correlations with serum ELISA, indirect immunofluorescence and disease severity
Anti-desmoglein (anti-Dsg) ELISA and indirect immunofluorescence (IIF) are used for the diagnosis of pemphigus vulgaris (PV). The value of salivary ELISA, serum ELISA, and IIF in the diagnosis of PV, and the correlation of salivary anti-Dsg1 and anti-Dsg3 ELISA with serum ELISA, serum and salivary IIF titers, and disease severity in patients with PV were evaluated. Fifty newly diagnosed patients with PV were enrolled in the study. Demographic data and disease-severity scores were recorded for each patient. Anti-Dsg1 and anti-Dsg3 ELISA and IIF were performed on both serum and salivary samples. Given the cut-off value of 20...
Source: Acta Dermatovenerologica Croatica - July 4, 2018 Category: Dermatology Source Type: research
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Source: Acta Dermatovenerologica Croatica - July 3, 2018 Category: Dermatology Source Type: research
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Source: Acta Dermatovenerologica Croatica - May 3, 2018 Category: Dermatology Source Type: research
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Source: Acta Dermatovenerologica Croatica - April 30, 2018 Category: Dermatology Source Type: research
