Lung Cancer Screening—why do it? Tobacco, the History of Screening and Future Challenges
The US National Lung Cancer Screening Trial (NLST) begun in 2002 was halted early in October 2010 due to clear evidence that annual screening with low dose computed tomography (LDCT) scans led to decreased mortality in the screened population. The NLST posted a 20% reduction in deaths from lung cancer and a 7% decrease in all-cause mortality.1 Building on decades of research and previous trials, it was the first randomized controlled clinical trial to incontrovertibly validate a mortality benefit from lung cancer screening. (Source: Seminars in Roentgenology)
Source: Seminars in Roentgenology - October 17, 2014 Category: Radiology Authors: Patricia M. de Groot, Brett W. Carter, Myrna C.B. Godoy, Reginald F. Munden Source Type: research
Screening for peripheral artery disease
Peripheral artery disease (PAD) is a common condition, which is strongly linked with increased risk of atherosclerotic disease at other sites in the aging population. Much of the population who are considered high-risk for PAD are also considered as high-risk for other cardiovascular diseases, and are candidates for many of the proposed risk-reduction medical interventions. The intention behind screening for PAD in asymptomatic populations is two-fold: to improve outcomes from PAD, and to prevent adverse cardio- and cerebrovascular (CVD) events. (Source: Seminars in Roentgenology)
Source: Seminars in Roentgenology - October 17, 2014 Category: Radiology Authors: James Sorensen, Sonia Wilks, Alexis D. Hall, Tam T.T. Huynh Source Type: research
Clinical Applications of Pediatric PET/MRI
The recent introduction of positron emission tomography/ magnetic resonance imaging (PET/MRI) to the realm of clinical imaging has created an opportunity for improved pediatric patient care, not only from a logistics perspective, simplifying diagnostic workflow in patients requiring multiple studies during their treatment, but also from diagnostic accuracy imaging and radiation exposure standpoints. By combining the metabolic information of positron emission tomography (PET) and the high soft tissue contrast resolution and functional information of magnetic resonance imaging (MRI) in a single examination, diagnostic effica...
Source: Seminars in Roentgenology - October 6, 2014 Category: Radiology Authors: Sara R. Teixeira, Claudia Martinez-Rios, Lingzhi Hu, Barbara A. Bangert Source Type: research
Letter from the Guest Editor
Hybrid imaging has gained significant importance for diagnosis and treatment monitoring by offering co-registered molecular/anatomical information. The latest clinical advance is a combination of PET and MRI, which followed previous developments of PET/CT and SPECT/CT. PET/MR offers unique diagnostic opportunities combining the strengths of these two imaging modalities which are believed to be synergistic and complementary. Thus, PET/MR combines high anatomical detail as well as biochemical and functional information from MRI with metabolic and molecular information from PET. (Source: Seminars in Roentgenology)
Source: Seminars in Roentgenology - September 23, 2014 Category: Radiology Authors: Norbert Avril, Pablo R. Ros Source Type: research
Early response monitoring of receptor tyrosine kinase inhibitor therapy in metastatic renal cell carcinoma using [F-18]FLT-PET/MR
A 62-yr-old gentleman was admitted to the hospital with a two-month history of left flank pain and hematuria. Unenhanced computed tomography (CT) demonstrated a large, solid mass within the lower pole of the left kidney, measuring 10.9 x 9.5 cm (Fig. 1). The patient underwent radical nephrectomy with histopathology revealing a Fuhrman grade 2 clear cell renal cell carcinoma. A follow-up CT scan 14 months later demonstrated a large lobulated soft tissue mass in the left nephrectomy bed measuring 12 x 14 x 9 cm as well as multiple mesenteric nodules suggestive of disease recurrence. (Source: Seminars in Roentgenology)
Source: Seminars in Roentgenology - September 14, 2014 Category: Radiology Authors: Laia Valls, Christopher Hoimes, Andrew Sher, Lingzhi Hu, Zhenghong Lee, Raymond Muzic, Norbert Avril Tags: Case of the season Source Type: research
Potential Role of Positron Emission Tomography/Magnetic Resonance Imaging in Gastrointestinal and Abdominal Malignancies: Preliminary Experience
This article (1) reviews the established role and value of PET and MRI as individual imaging modalities in the workup of certain oncologic diseases within the abdomen and (2) reports our initial experience in this field to provide a perspective of the potential future role and expected value of PET-MR in these clinical scenarios. (Source: Seminars in Roentgenology)
Source: Seminars in Roentgenology - August 6, 2014 Category: Radiology Authors: Sara Reis Teixera, Andres A. Kohan, Raj Mohan Paspulati, Rong Rong, Karin Anna Herrmann Source Type: research
Potential Role of PET/MR in Gastrointestinal and Abdominal Malignancies: Preliminary Experience
Positron emission tomography / Magnetic resonance imaging (PET/MR) is a powerful emerging tool that by now has already proven promising for many applications in oncologic clinical settings. PET/MR is equivalent to PET/CT in most of the clinical indications in the abdomen or pelvis with the advantage to provide better soft tissue information. The present article is designed to review the established role and value of positron emission tomography (PET) and magnetic resonance imaging (MRI) as individual imaging modalities in the workup of certain abdominal oncologic diseases and to report our own initial experience in order t...
Source: Seminars in Roentgenology - August 6, 2014 Category: Radiology Authors: Sara Reis Teixera, Raj Mohan Paspulati, Andres Kohan, Rong Rong, Karin Anna Herrmann Source Type: research
Artifacts and Diagnostic Pitfalls in Positron Emission Tomography-Magnetic Resonance Imaging
Positron emission tomography-magnetic resonance (PET-MR) is a new hybrid imaging modality that has recently been introduced in clinical practice for oncologic imaging and is increasingly being used in various clinical indications.1-5 PET-MR unifies the complementary capabilities of magnetic resonance imaging (MRI) and PET in a single imaging modality. Excellent anatomical and morphologic information with high soft tissue resolution and contrast from MRI and the best possible molecular, functional, and physiological information from PET are complementary and have the potential to provide maximum diagnostic information in a ...
Source: Seminars in Roentgenology - August 6, 2014 Category: Radiology Authors: Claudia Martinez-Rios, Raymond F. Muzic, Frank P. DiFilippo, Lingzhi Hu, Christian Rubbert, Karin A. Herrmann Source Type: research
Potential Role of PET/MR in Gastrointestinal and Abdominal Malignancies: Preliminary Experience
Positron emission tomography / Magnetic resonance imaging (PET/MR) is a powerful emerging tool that by now has already proven promising for many applications in oncologic clinical settings. PET/MR is equivalent to PET/CT in most of the clinical indications in the abdomen or pelvis with the advantage to provide better soft tissue information. The present article is designed to review the established role and value of positron emission tomography (PET) and magnetic resonance imaging (MRI) as individual imaging modalities in the workup of certain abdominal oncologic diseases and to report our own initial experience in order t...
Source: Seminars in Roentgenology - August 6, 2014 Category: Radiology Authors: Sara Reis Teixera, Raj Mohan Paspulati, Andres Kohan, Rong Rong, Karin Anna Herrmann Source Type: research
Artifacts and Diagnostic Pitfalls in Positron Emission Tomography-Magnetic Resonance Imaging
Positron emission tomography-magnetic resonance (PET-MR) is a new hybrid imaging modality that has recently been introduced in clinical practice for oncologic imaging and is increasingly being used in various clinical indications.1-5 PET-MR unifies the complementary capabilities of magnetic resonance imaging (MRI) and PET in a single imaging modality. Excellent anatomical and morphologic information with high soft tissue resolution and contrast from MRI and the best possible molecular, functional, and physiological information from PET are complementary and have the potential to provide maximum diagnostic information in a ...
Source: Seminars in Roentgenology - August 6, 2014 Category: Radiology Authors: Claudia Martinez-Rios, Raymond F. Muzic, Frank P. DiFilippo, Lingzhi Hu, Christian Rubbert, Karin A. Herrmann Source Type: research
Whole-Body Positron Emission Tomography-Magnetic Resonance in Breast Cancer
Hybrid positron emission tomography (PET)-magnetic resonance (MR) technology has recently been introduced into the market, appearing in the clinical setting in 2007.1,2 Whether designed as a sequential or simultaneous system, the hybrid PET-MR produces high-resolution anatomical, biological, and functional imaging. Given the limited approved indications of PET/computed tomography (CT) in patients with breast cancer, it is understandable that the potential role of PET-MR in such patients remains to be determined. (Source: Seminars in Roentgenology)
Source: Seminars in Roentgenology - August 4, 2014 Category: Radiology Authors: Andrew Sher, Laia Valls, Raymond F. Muzic, Donna Plecha, Norbert Avril Source Type: research
