Early response monitoring of receptor tyrosine kinase inhibitor therapy in metastatic renal cell carcinoma using [F-18]FLT-PET/MR

A 62-yr-old gentleman was admitted to the hospital with a two-month history of left flank pain and hematuria. Unenhanced computed tomography (CT) demonstrated a large, solid mass within the lower pole of the left kidney, measuring 10.9 x 9.5 cm (Fig. 1). The patient underwent radical nephrectomy with histopathology revealing a Fuhrman grade 2 clear cell renal cell carcinoma. A follow-up CT scan 14 months later demonstrated a large lobulated soft tissue mass in the left nephrectomy bed measuring 12 x 14 x 9 cm as well as multiple mesenteric nodules suggestive of disease recurrence.
Source: Seminars in Roentgenology - Category: Radiology Authors: Tags: Case of the season Source Type: research