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Is abnormal glucose tolerance or diabetes a risk factor for knee, hip, or hand osteoarthritis? a systematic review
Diabetes (DM) and osteoarthritis (OA) are two common co-existing chronic conditions. However, whether this is due to shared risk factors or may differ between joints is unclear. We performed a systematic review to determine whether abnormal glucose metabolism is a risk factor for knee, hip and hand OA, separately, independent of age and obesity. (Source: Seminars in Arthritis and Rheumatism)
Source: Seminars in Arthritis and Rheumatism - February 20, 2018 Category: Rheumatology Authors: Luke P. Dawson, Jessica Fairley, Michelle Papandony, Sultana Monira Hussain, Flavia M. Cicuttini, Anita E. Wluka Source Type: research

Predictors of hypogammaglobulinemia during rituximab maintenance therapy in rheumatoid arthritis: a 12-year longitudinal multi-center study
Rituximab (RTX) is an anti-CD20 monoclonal antibody that selectively depletes B-cell population. Thus, it presents a potential risk for the development of hypogammaglobulinemia and related infectious events. Our aim was to identify predictors of hypogammaglobulinemia in RA patients long-term treated with RTX. (Source: Seminars in Arthritis and Rheumatism)
Source: Seminars in Arthritis and Rheumatism - February 20, 2018 Category: Rheumatology Authors: G. Boleto, J. Avouac, J. Wipff, M. Forien, M. Dougados, C. Roux, A. Kahan, P. Dieude, Y. Allanore Source Type: research

Cardiovascular disease in ANCA-associated vasculitis: the danger lurking beneath the surface!
We read with great interest the recent article by Bai et al. [1] reporting that, along with traditional risk factors, higher disease activity at baseline also independently predicted cardiovascular events (CVE) and cardiovascular mortality in a large cohort of AAV. We discuss these findings in the light of recent literature. (Source: Seminars in Arthritis and Rheumatism)
Source: Seminars in Arthritis and Rheumatism - February 20, 2018 Category: Rheumatology Authors: Durga Prasanna Misra, Aman Sharma, Vikas Agarwal Source Type: research

Clinical value of autoantibodies for lupus myelitis and its subtypes: A systematic review
We conducted a systematic review to investigate the clinical value of clinical characteristics and autoantibodies, especially lupus-specific antibodies, for lupus myelitis and its subtypes. (Source: Seminars in Arthritis and Rheumatism)
Source: Seminars in Arthritis and Rheumatism - February 15, 2018 Category: Rheumatology Authors: Hiroshi Oiwa, Akira Kuriyama, Tomoyasu Matsubara, Eiji Sugiyama Source Type: research

Dactylitis: A hallmark of psoriatic arthritis
Dactylitis —long considered a hallmark clinical feature of psoriatic arthritis (PsA)—occurs in 16–49% of patients with PsA. In this review, we discuss the pathology of dactylitis in PsA and clinical and imaging tools used to diagnose and monitor dactylitis. (Source: Seminars in Arthritis and Rheumatism)
Source: Seminars in Arthritis and Rheumatism - February 15, 2018 Category: Rheumatology Authors: Gurjit S. Kaeley, Lihi Eder, Sibel Z. Aydin, Marwin Gutierrez, Catherine Bakewell Source Type: research

The effect of cigarette smoking on the clinical and serological phenotypes of polymyositis and dermatomyositis
Cigarette smoking is associated with immune-mediated disorders. We explored the contribution of smoking to polymyositis (PM) and dermatomyositis (DM) phenotypes and attempted to determine whether cigarette smoking effects differ by race and genotype. (Source: Seminars in Arthritis and Rheumatism)
Source: Seminars in Arthritis and Rheumatism - February 15, 2018 Category: Rheumatology Authors: Adam Schiffenbauer, Sara Faghihi-Kashani, Terrence P. O ’Hanlon, Willy A. Flegel, Sharon D. Adams, Ira N. Targoff, Chester V. Oddis, Steven R. Ytterberg, Rohit Aggarwal, Lisa Christopher-Stine, Ejaz A. Shamim, Paul F. Dellaripa, Sonye K. Danoff, Andrew Source Type: research

Does nailfold capillaroscopy help predict future outcomes in systemic sclerosis? A systematic literature review
Nailfold capillaroscopy (NC) is an important diagnostic tool in systemic sclerosis (SSc). Confirmation of NC as a prognostic factor could facilitate earlier intervention and slow disease progression in SSc. We undertook a systematic literature review to evaluate the prognostic value of NC in predicting SSc disease progression. (Source: Seminars in Arthritis and Rheumatism)
Source: Seminars in Arthritis and Rheumatism - February 15, 2018 Category: Rheumatology Authors: Dolcie Paxton, John D. Pauling Source Type: research

Dactylitis: A hallmark of psoriatic arthritis
Dactylitis —long considered a hallmark clinical feature of psoriatic arthritis (PsA)—occurs in 16% to 49% of patients with PsA. In this review, we discuss the pathology of dactylitis in PsA and clinical and imaging tools used to diagnose and monitor dactylitis. (Source: Seminars in Arthritis and Rheumatism)
Source: Seminars in Arthritis and Rheumatism - February 15, 2018 Category: Rheumatology Authors: Gurjit S. Kaeley, Lihi Eder, Sibel Z. Aydin, Marwin Gutierrez, Catherine Bakewell Source Type: research

The impact of cigarette smoking on the clinical and serological phenotypes of polymyositis and dermatomyositis
Cigarette smoking is associated with immune-mediated disorders. We explored the contribution of smoking to polymyositis (PM) and dermatomyositis (DM) phenotypes and attempted to determine whether cigarette smoking effects differ by race and genotype. (Source: Seminars in Arthritis and Rheumatism)
Source: Seminars in Arthritis and Rheumatism - February 15, 2018 Category: Rheumatology Authors: Adam Schiffenbauer, Sara Faghihi-Kashani, Terrence P. O ’Hanlon, Willy A. Flegel, Sharon D. Adams, Ira N. Targoff, Chester V. Oddis, Steven R. Ytterberg, Rohit Aggarwal, Lisa Christopher-Stine, Ejaz A. Shamim, Paul F. Dellaripa, Sonye K. Danoff, Andrew Source Type: research

Does nailfold capillaroscopy help predict future outcomes in systemic sclerosis? A systematic literature review
Nailfold capillaroscopy (NC) is an important diagnostic tool in systemic sclerosis (SSc). Confirmation of NC as a prognostic factor could facilitate earlier intervention and slow disease progression in SSc. We undertook a systematic literature review to evaluate the prognostic value of NC in predicting SSc disease progression (Source: Seminars in Arthritis and Rheumatism)
Source: Seminars in Arthritis and Rheumatism - February 15, 2018 Category: Rheumatology Authors: Dolcie Paxton, John D. Pauling Source Type: research

Predictors of the effect of bariatric surgery on knee osteoarthritis pain
Bariatric surgery reduces obesity and knee osteoarthritis (OA) pain, but some patients improve more than others. We aimed to identify characteristics that predict this knee pain improvement. (Source: Seminars in Arthritis and Rheumatism)
Source: Seminars in Arthritis and Rheumatism - February 8, 2018 Category: Rheumatology Authors: Shannon X. Chen, Fernando A. Bomfim, Heekoung A. Youn, Christine Ren-Fielding, Jonathan Samuels Source Type: research

Patient characteristics predict the effect of bariatric surgery on knee osteoarthritis pain
Bariatric surgery reduces obesity and knee osteoarthritis (OA) pain, but some patients improve more than others. We aimed to identify patient characteristics that predict knee pain reduction in obese patients after bariatric surgery. (Source: Seminars in Arthritis and Rheumatism)
Source: Seminars in Arthritis and Rheumatism - February 8, 2018 Category: Rheumatology Authors: Shannon X. Chen, Fernando A. Bomfim, Heekoung A. Youn, Christine Ren-Fielding, Jonathan Samuels Source Type: research