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Comparing ultraviolet light A photo(chemo)therapy with Methotrexate protocol in childhood localized scleroderma: Evidence from systematic review and meta-analysis approach
Localized scleroderma is a skin fibrosing disorder that, if untreated, may result in severe disability. The purpose of this systematic review is to compare the present evidence concerning the effectiveness of Methotrexate versus phototherapy, alone or associated with Psoralen, in childhood localized scleroderma. (Source: Seminars in Arthritis and Rheumatism)
Source: Seminars in Arthritis and Rheumatism - March 14, 2018 Category: Rheumatology Authors: Edoardo Marrani, Ivan Foeldvari, Jordi Anton Lopez, Rolando Cimaz, Gabriele Simonini Source Type: research

Baseline patient reported outcomes are more consistent predictors of long-term functional disability than laboratory, imaging or joint count data in patients with early inflammatory arthritis: A systematic review
To assess baseline predictors of long-term functional disability in patients with inflammatory arthritis (IA). (Source: Seminars in Arthritis and Rheumatism)
Source: Seminars in Arthritis and Rheumatism - March 14, 2018 Category: Rheumatology Authors: James M. Gwinnutt, Charlotte A. Sharp, Deborah P.M. Symmons, Mark Lunt, Suzanne M.M. Verstappen Source Type: research

Comparing ultraviolet light A photo(chemo)therapy with Methotrexate protocol in childhood localized Scleroderma: Evidence from systematic review and meta-analysis approach
Localized scleroderma is a skin fibrosing disorder that, if untreated, may result in severe disability. The purpose of this systematic review is to compare the present evidence concerning the effectiveness of Methotrexate versus phototherapy, alone or associated with Psoralen, in childhood localized scleroderma. (Source: Seminars in Arthritis and Rheumatism)
Source: Seminars in Arthritis and Rheumatism - March 14, 2018 Category: Rheumatology Authors: Edoardo Marrani, Ivan Foeldvari, Jord Anton Lopez, Rolando Cimaz, Gabriele Simonini Source Type: research

Patterns of peripheral joint involvement in psoriatic arthritis —Symmetric, ray and/or row?
We sought to examine whether joint involvement in psoriatic arthritis (PsA) follows a symmetric, ray, and/or row pattern using longitudinal data. (Source: Seminars in Arthritis and Rheumatism)
Source: Seminars in Arthritis and Rheumatism - March 9, 2018 Category: Rheumatology Authors: Vinod Chandran, Lynne Stecher, Vern Farewell, Dafna D. Gladman Source Type: research

Patterns of Peripheral Joint Involvement in Psoriatic Arthritis - Symmetric, Ray and/or Row?
We sought to examine whether joint involvement in psoriatic arthritis (PsA) follows a symmetric, ray, and/or row pattern using longitudinal data. (Source: Seminars in Arthritis and Rheumatism)
Source: Seminars in Arthritis and Rheumatism - March 9, 2018 Category: Rheumatology Authors: Vinod Chandran, Lynne Stecher, Vern Farewell, Dafna D. Gladman Source Type: research

Efficacy of curcumin and Boswellia for knee osteoarthritis: Systematic review and meta-analysis
The unfavorable safety profiles of commonly prescribed knee osteoarthritis (OA) treatments have led clinicians and patients to seek safer alternatives. Research has suggested that curcuminoid and boswellia formulations could moderate key inflammatory pathways that are associated with worsening symptoms and disease progression. We conducted a systematic review and meta-analysis to assess the efficacy and safety of these treatments vs. placebo or NSAIDs for knee OA. (Source: Seminars in Arthritis and Rheumatism)
Source: Seminars in Arthritis and Rheumatism - March 9, 2018 Category: Rheumatology Authors: Raveendhara R. Bannuru, Mikala C. Osani, Fatimah Al-Eid, Chenchen Wang Source Type: research

Patterns of Peripheral Joint Involvement in Psoriatic Arthritis - Symmetric, Ray and/or Row?
We sought to examine whether joint involvement in psoriatic arthritis (PsA) follows a symmetric, ray, and/or row pattern using longitudinal data. (Source: Seminars in Arthritis and Rheumatism)
Source: Seminars in Arthritis and Rheumatism - March 9, 2018 Category: Rheumatology Authors: Vinod Chandran, Lynne Stecher, Vern Farewell, Dafna D. Gladman Source Type: research

Efficacy of Curcumin and Boswellia for Knee Osteoarthritis: Systematic Review and Meta-Analysis
The unfavorable safety profiles of commonly prescribed knee osteoarthritis (OA) treatments have led clinicians and patients to seek safer alternatives. Research has suggested that curcuminoid and boswellia formulations could moderate key inflammatory pathways that are associated with worsening symptoms and disease progression. We conducted a systematic review and meta-analysis to assess the efficacy and safety of these treatments vs. placebo or NSAIDs for knee OA. (Source: Seminars in Arthritis and Rheumatism)
Source: Seminars in Arthritis and Rheumatism - March 9, 2018 Category: Rheumatology Authors: Raveendhara R. Bannuru, Mikala C. Osani, Fatimah Al-Eid, Chenchen Wang Source Type: research

How is symptom flare defined in musculoskeletal conditions: A systematic review
To systematically review the definitions for “flare” in musculoskeletal conditions, the derivation processes, and validation of definitions for the 12 most burdensome musculoskeletal conditions. (Source: Seminars in Arthritis and Rheumatism)
Source: Seminars in Arthritis and Rheumatism - February 26, 2018 Category: Rheumatology Authors: Nathalia Costa, Manuela L. Ferreira, Marita Cross, Joanna Makovey, Paul W. Hodges Source Type: research

Phenotypic characterization of patients with rheumatologic manifestations of common variable immunodeficiency
Patients with common variable immunodeficiency (CVID) have a higher incidence of rheumatologic disorders. To delineate this clinical association, we investigated the phenotypic features of patients with CVID affected by these conditions. (Source: Seminars in Arthritis and Rheumatism)
Source: Seminars in Arthritis and Rheumatism - February 22, 2018 Category: Rheumatology Authors: Maria J. Gutierrez, Kathleen E. Sullivan, Ramsay Fuleihan, The USIDNET Consortium, Clifton O. Bingham Source Type: research

Predicting eventual development of lupus nephritis at the time of diagnosis of systemic lupus erythematosus
To investigate factors predictive of future lupus nephritis development when systemic lupus erythematosus (SLE) is diagnosed. (Source: Seminars in Arthritis and Rheumatism)
Source: Seminars in Arthritis and Rheumatism - February 22, 2018 Category: Rheumatology Authors: Oh Chan Kwon, Jung Sun Lee, Byeongzu Ghang, Yong-Gil Kim, Chang-Keun Lee, Bin Yoo, Seokchan Hong Source Type: research

Low disease activity —irrespective of serologic status at baseline—associated with reduction of corticosteroid dose and number of flares in patients with systemic lupus erythematosus treated with belimumab: A real-life observational study
Low disease activity is a validated target of current systemic lupus erythematosus (SLE) therapy. The aim of this study was to assess the ability of belimumab to achieve low disease activity states in real-life settings. (Source: Seminars in Arthritis and Rheumatism)
Source: Seminars in Arthritis and Rheumatism - February 22, 2018 Category: Rheumatology Authors: Antonis Fanouriakis, Christina Adamichou, Sofia Koutsoviti, Stylianos Panopoulos, Chrysanthi Staveri, Anastasia Klagou, Christina Tsalapaki, Lamprini Pantazi, Styliani Konsta, Clio P. Mavragani, Despoina Dimopoulou, Styliani Ntali, Georgios Katsikas, Kyri Source Type: research

Measurement properties of patient reported outcome measures for spondyloarthritis: A systematic review
This systematic review aimed to identify studies investigating measurement properties of patient reported outcome measures (PROMs) for spondyloarthritis (SpA), and to evaluate their methodological quality and level of evidence relating to the measurement properties of PROMs. (Source: Seminars in Arthritis and Rheumatism)
Source: Seminars in Arthritis and Rheumatism - February 22, 2018 Category: Rheumatology Authors: Kelly Png, Yu Heng Kwan, Ying Ying Leung, Jie Kie Phang, Jia Qi Lau, Ka Keat Lim, Eng Hui Chew, Lian Leng Low, Chuen Seng Tan, Julian Thumboo, Warren Fong, Truls Østbye Source Type: research

Predictive value of early structural changes on radiographs and MRI for incident clinical and radiographic knee osteoarthritis in overweight and obese women
To determine the predictive value of tibiofemoral (TF), patellofemoral (PF) MRI osteoarthritis (OA), and Kellgren and Lawrence grade 1 (KLG1) for the incidence of knee OA (clinical and/or radiological signs) at 2.5 and 6.5 years follow-up in a high-risk cohort. (Source: Seminars in Arthritis and Rheumatism)
Source: Seminars in Arthritis and Rheumatism - February 22, 2018 Category: Rheumatology Authors: Claudia Bernadette Maria Bijen, Jos Runhaar, Joanne Bernadine Marie Rijkels-Otters, Edwin Hong Gwan Oei, Sebastia Margaretha Agatha Bierma-Zeinstra Source Type: research