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Diagnostic value of screening enzyme immunoassays compared to indirect immunofluorescence for anti-nuclear antibodies in patients with systemic rheumatic diseases: A systematic review and meta-analysis
This study aimed to review and compare the diagnostic accuracy of the screening enzyme immunoassay (SEIA) and indirect immunofluorescence (IIF) as anti-nuclear antibody (ANA) screening assays for patients with systemic rheumatic diseases (SRDs), including systemic lupus erythematosus (SLE), Sj ögren’s syndrome (SS), and systemic sclerosis (SSc). (Source: Seminars in Arthritis and Rheumatism)
Source: Seminars in Arthritis and Rheumatism - February 4, 2018 Category: Rheumatology Authors: Seri Jeong, Dahae Yang, Woonhyoung Lee, Geun-Tae Kim, Hyon-Suk Kim, Hyeong Sik Ahn, Hyun Jung Kim Source Type: research

Diagnostic value of screening enzyme immunoassays compared to indirect immunofluorescence for anti-nuclear antibodies in patients with systemic rheumatic diseases: A systematic review and meta-analysis
This study aimed to review and compare the diagnostic accuracy of the screening enzyme immunoassay (SEIA) and indirect immunofluorescence (IIF) as anti-nuclear antibody (ANA) screening assays for patients with systemic rheumatic diseases (SRDs), including systemic lupus erythematosus (SLE), Sj ögren's syndrome (SS), and systemic sclerosis (SSc). (Source: Seminars in Arthritis and Rheumatism)
Source: Seminars in Arthritis and Rheumatism - February 4, 2018 Category: Rheumatology Authors: Seri Jeong, Dahae Yang, Woonhyoung Lee, Geun-Tae Kim, Hyon-Suk Kim, Hyeong Sik Ahn, Hyun Jung Kim Source Type: research

Pulmonary manifestations in late versus early systemic lupus erythematosus: A systematic review and meta-analysis
Phenotypes differ between late- and early-onset systemic lupus erythematosus (SLE). Prior studies suggested that there may be more pulmonary disease among late-onset patients. Our objective was to perform a systematic review and meta-analysis to evaluate the differences in pulmonary manifestations in late- versus early-onset SLE. (Source: Seminars in Arthritis and Rheumatism)
Source: Seminars in Arthritis and Rheumatism - February 3, 2018 Category: Rheumatology Authors: Jennifer L. Medlin, Karen E. Hansen, Sara S. McCoy, Christie M. Bartels Source Type: research

Pulmonary manifestations in late versus early systemic lupus erythematosus: A systematic review and meta-analysis
Phenotypes differ between late and early-onset systemic lupus erythematosus (SLE). Prior studies suggested that there may be more pulmonary disease among late-onset patients. Our objective was to perform a systematic review and meta-analysis to evaluate the differences in pulmonary manifestations in late- versus early-onset SLE. (Source: Seminars in Arthritis and Rheumatism)
Source: Seminars in Arthritis and Rheumatism - February 3, 2018 Category: Rheumatology Authors: Jennifer L. Medlin, Karen E. Hansen, Sara S. McCoy, Christie M. Bartels Source Type: research

Reducing glucocorticoid duration in ANCA-associated vasculitis: A pilot trial
We examined whether an 8-week glucocorticoid course in combination with rituximab (RTX) would induce disease remission in patients with AAV. (Source: Seminars in Arthritis and Rheumatism)
Source: Seminars in Arthritis and Rheumatism - February 2, 2018 Category: Rheumatology Authors: Eli M. Miloslavsky, John L. Niles, Zachary S. Wallace, Frank B. Cortazar, Ana Fernandes, Karen Laliberte, John H. Stone Source Type: research

Reducing glucocorticoid duration in anca-associated vasculitis: A pilot trial
We examined whether an 8-week glucocorticoid course in combination with rituximab (RTX) would induce disease remission in patients with AAV. (Source: Seminars in Arthritis and Rheumatism)
Source: Seminars in Arthritis and Rheumatism - February 2, 2018 Category: Rheumatology Authors: Eli M. Miloslavsky, John L. Niles, Zachary S. Wallace, Frank B. Cortazar, Ana Fernandes, Karen Laliberte, John H. Stone Source Type: research

Efficacy and safety of repeated courses of hyaluronic acid injections for knee osteoarthritis: A systematic review
Hyaluronic acid (HA) is a commonly prescribed intra-articular (IA) therapy for knee osteoarthritis (OA). While a single series of IA-HA has been well studied, the efficacy and safety of repeated courses of IA-HA injection therapy in knee OA patients have not been evaluated as frequently. (Source: Seminars in Arthritis and Rheumatism)
Source: Seminars in Arthritis and Rheumatism - January 19, 2018 Category: Rheumatology Authors: Roy Altman, Josh Hackel, Faizan Niazi, Peter Shaw, Mathew Nicholls Source Type: research

Efficacy and Safety of Repeated Courses of Hyaluronic Acid Injections for Knee Osteoarthritis: A Systematic Review
Hyaluronic acid (HA) is a commonly prescribed intra-articular (IA) therapy for knee osteoarthritis (OA). While a single series of IA-HA has been well studied, the efficacy and safety of repeated courses of IA-HA injection therapy in knee OA patients have not been evaluated as frequently. (Source: Seminars in Arthritis and Rheumatism)
Source: Seminars in Arthritis and Rheumatism - January 19, 2018 Category: Rheumatology Authors: Roy Altman, Josh Hackel, Faizan Niazi, Peter Shaw, Mathew Nicholls Source Type: research

Periarticular bone predicts knee osteoarthritis progression: Data from the Osteoarthritis Initiative
Osteoarthritis (OA) is a disease with a substantial public health burden. Quantitative assessments of periarticular bone may be a biomarker capable of monitoring early disease progression. The purpose of this study was to evaluate whether measures of periarticular bone associate with longitudinal structural progression. (Source: Seminars in Arthritis and Rheumatism)
Source: Seminars in Arthritis and Rheumatism - January 17, 2018 Category: Rheumatology Authors: Grace H. Lo, Erika Schneider, Jeffrey B. Driban, Lori Lyn Price, David J. Hunter, Charles B. Eaton, Marc C. Hochberg, Rebecca D. Jackson, C. Kent Kwoh, Michael C. Nevitt, John A. Lynch, Timothy E. McAlindon, For The OAI Investigators Group Source Type: research

Analysis of mortality in a cohort of 650 cases of bacteremic osteoarticular infections
The mortality of patients with bacteremic osteoarticular infections (B-OAIs) is poorly understood. Whether certain types of OAIs carry higher mortality or interventions like surgical debridement can improve prognosis, are unclarified questions. (Source: Seminars in Arthritis and Rheumatism)
Source: Seminars in Arthritis and Rheumatism - January 17, 2018 Category: Rheumatology Authors: Joan Gomez-Junyent, Oscar Murillo, Imma Grau, Eva Benavent, Alba Ribera, Xavier Cabo, Fe Tubau, Javier Ariza, Roman Pallares Source Type: research

Periarticular Bone Predicts Knee Osteoarthritis Progression: Data from the Osteoarthritis Initiative
Osteoarthritis (OA) is a disease with a substantial public health burden. Quantitative assessments of peri-articular bone may be a biomarker capable of monitoring early disease progression. The purpose of this study was to evaluate whether measures of peri-articular bone associate with longitudinal structural progression. (Source: Seminars in Arthritis and Rheumatism)
Source: Seminars in Arthritis and Rheumatism - January 17, 2018 Category: Rheumatology Authors: Grace H. Lo, Erika Schneider, Jeffrey B. Driban, Lori Lyn Price, David J. Hunter, Charles B. Eaton, Marc C. Hochberg, Rebecca D. Jackson, C. Kent Kwoh, Michael Nevitt, John A. Lynch, Timothy E. McAlindon, for the OAI Investigators Group Source Type: research

Analysis of Mortality in a Cohort of 650 Cases of Bacteremic Osteoarticular Infections
The mortality of patients with bacteremic osteoarticular infections (B-OAIs) is poorly understood. Whether certain types of OAIs carry higher mortality or interventions like surgical debridement can improve prognosis, are unclarified questions. (Source: Seminars in Arthritis and Rheumatism)
Source: Seminars in Arthritis and Rheumatism - January 17, 2018 Category: Rheumatology Authors: Joan Gomez-Junyent, Oscar Murillo, Imma Grau, Eva Benavent, Alba Ribera, Xavier Cabo, Fe Tubau, Javier Ariza, Roman Pallares Source Type: research

Hydralazine-associated vasculitis: Overlapping features of drug-induced lupus and vasculitis
Hydralazine is an antihypertensive medication that has been associated with drug-induced lupus erythematosus (DIL) as well as ANCA-associated vasculitis (AAV). Although rare, early diagnosis is critical since drug cessation is the mainstay of therapy. This retrospective study aims to characterize the clinical, laboratory, and histopathologic features of this disease. (Source: Seminars in Arthritis and Rheumatism)
Source: Seminars in Arthritis and Rheumatism - January 12, 2018 Category: Rheumatology Authors: Bharat Kumar, Jennifer Strouse, Melissa Swee, Petar Lenert, Manish Suneja Source Type: research

Hydralazine-Associated Vasculitis: Overlapping Features of Drug-Induced Lupus and Vasculitis
Hydralazine is an antihypertensive medication that has been associated with drug-induced lupus erythematosus (DIL) as well as ANCA-associated vasculitis (AAV). Although rare, early diagnosis is critical since drug cessation is the mainstay of therapy. This retrospective study aims to characterize the clinical, laboratory, and histopathologic features of this disease. (Source: Seminars in Arthritis and Rheumatism)
Source: Seminars in Arthritis and Rheumatism - January 12, 2018 Category: Rheumatology Authors: Bharat Kumar, Jennifer Strouse, Melissa Swee, Petar Lenert, Manish Suneja Source Type: research

Paternal exposure to antirheumatic drugs —What physicians should know: Review of the literature
Reproduction capacity and long-term preserved hormonal function are important aspects with big impacts on patients ’ quality of life. Updated information on the interaction between drug therapy and reproductive function is essential when discussing family planning with patients. Currently, limited data is published regarding paternal exposure to different medications. Thus, it may be a challenge for the practi tioner to choose the right therapy for a young male patient. Therefore we reviewed the literature, for effects of antirheumatic drugs on male gonadal function with a focus on spermatogenesis and offspring. (Source:...
Source: Seminars in Arthritis and Rheumatism - January 11, 2018 Category: Rheumatology Authors: M.C. Micu, M. Ostensen, P.M. Villiger, R. Micu, R. Ionescu Source Type: research