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Presence of comorbidities and prognosis of clinical symptoms in knee and/or hip osteoarthritis: A systematic review and meta-analysis
(i) To determine the association between the presence of comorbidities and severity of pain and physical dysfunction in people with knee and/or hip osteoarthritis; (ii) to explore associations between specific comorbidities (cardiac disease and/or hypertension, diabetes, depression, and back pain) and symptom severity. (Source: Seminars in Arthritis and Rheumatism)
Source: Seminars in Arthritis and Rheumatism - October 30, 2017 Category: Rheumatology Authors: Patrick Calders, Ans Van Ginckel Source Type: research

Patient-perceived health service needs in inflammatory arthritis: A systematic scoping review
Care that is patient-centred is more likely to be sustainable and associated with improved health outcomes. This approach to care requires an understanding of patients ’ health service needs, yet few studies have directly investigated the perceived health service needs of people with inflammatory arthritis. (Source: Seminars in Arthritis and Rheumatism)
Source: Seminars in Arthritis and Rheumatism - October 30, 2017 Category: Rheumatology Authors: Julian D Segan, Louisa Chou, Kathryn L. Connelly, Andrew M. Briggs, Maheeka Seneviwickrama, Kaye Sullivan, Flavia M. Cicuttini, Anita E. Wluka Source Type: research

Rheumatologic symptoms in oncologic patients on PD-1 inhibitors
Immune check-point inhibitors are effective cancer therapies that have been associated with immune related adverse events (irAEs). Recent reports of irAEs describe symptoms resembling classic rheumatologic syndromes, most notably associated with cytotoxic T-lymphocyte-associated protein 4 (CTLA-4) inhibitor blockade. There are limited reports of rheumatologic disease associated with programmed cell death protein-1 (PD-1) inhibitors. Here, we describe a case series of four patients presenting to the Brigham and Women's Hospital (BWH) Arthritis Center with de novo polymyalgia rheumatica (PMR)-type conditions and/or periphera...
Source: Seminars in Arthritis and Rheumatism - October 30, 2017 Category: Rheumatology Authors: Wilson F. Kuswanto, Lindsey A. MacFarlane, Lydia Gedmintas, Alexandra Mulloy, Toni K. Choueiri, Bonnie Bermas Source Type: research

Presence of comorbidities and prognosis of clinical symptoms in knee and/or hip osteoarthritis: A systematic review and meta-analysis
(i) To determine the association between the presence of comorbidities and severity of pain and physical dysfunction in people with knee and/or hip osteoarthritis; (ii) To explore associations between specific comorbidities (cardiac disease and/or hypertension, diabetes, depression, back pain) and symptom severity. (Source: Seminars in Arthritis and Rheumatism)
Source: Seminars in Arthritis and Rheumatism - October 30, 2017 Category: Rheumatology Authors: Patrick Calders, Ans Van Ginckel Source Type: research

Carotid and femoral atherosclerosis in antiphospholipid syndrome: Equivalent risk with diabetes mellitus in a case –control study
Antiphospholipid syndrome (APS) may carry a worse prognosis for vascular complications when co-existing with subclinical atherosclerosis; however, the association between the two conditions remains ambiguous. (Source: Seminars in Arthritis and Rheumatism)
Source: Seminars in Arthritis and Rheumatism - October 23, 2017 Category: Rheumatology Authors: Evrydiki Kravvariti, George Konstantonis, Nikolas Tentolouris, Petros P. Sfikakis, Maria G. Tektonidou Source Type: research

Carotid and femoral atherosclerosis in Antiphospholipid Syndrome: equivalent risk with Diabetes mellitus in a case-control study
Antiphospholipid syndrome (APS) may carry a worse prognosis for vascular complications when co-existing with subclinical atherosclerosis, however, the association between the two conditions remains ambiguous. (Source: Seminars in Arthritis and Rheumatism)
Source: Seminars in Arthritis and Rheumatism - October 23, 2017 Category: Rheumatology Authors: Evrydiki Kravvariti, George Konstantonis, Nikolas Tentolouris, Petros P. Sfikakis, Maria G. Tektonidou Source Type: research

Intra cranial granulomatous disease in common variable immunodeficiency: Case series and review of the literature
Common variable immunodeficiency (CVID) is typically characterized by hypogammaglobulinemia and often but not always recurrent infections. Paradoxically, 8 –22% of patients with CVID develop granulomatous disease. Granulomata have been described in many organs including the lungs, skin, liver, spleen, kidneys, eyes, lymph nodes, and intestines. Data about central nervous system (CNS) involvement in CVID are extremely rare. We aim to describe a case s eries and include an extensive literature review of CNS involvement in CVID to understand the different features and patterns of the disease. (Source: Seminars in Arthritis and Rheumatism)
Source: Seminars in Arthritis and Rheumatism - October 20, 2017 Category: Rheumatology Authors: Catherine E. Najem, Jason Springer, Richard Prayson, Daniel A. Culver, James Fernandez, Jinny Tavee, Rula A. Hajj-Ali Source Type: research

Risk factors and clinical characteristics of deep knee infection in patients with intra-articular injections: A matched retrospective cohort analysis
Deep knee infection (DKI), consisting of sepsis arthritis (SA) and chronic low-grade infection (CLGI), is a rare but catastrophic adverse event that can result from intra-articular (IA) injections. The purpose of this study was to assess the risk factors for DKI and describe the clinical characteristics of DKI in patients who received IA injections. (Source: Seminars in Arthritis and Rheumatism)
Source: Seminars in Arthritis and Rheumatism - October 20, 2017 Category: Rheumatology Authors: Chi Xu, Haiwen Peng, Rui Li, Wei Chai, Xiang Li, Jun Fu, Kan Liu, Baozhan Yu, Chengqi Jia, Jiying Chen Source Type: research

Intra-cranial Granulomatous Disease in Common Variable Immunodeficiency: Case Series and Review of the Literature
Common variable immunodeficiency (CVID) is typically characterized by hypogammaglobulinemia and often but not always recurrent infections. Paradoxically, 8 –22% of patients with CVID develop granulomatous disease. Granulomata have been described in many organs including the lungs, skin, liver, spleen, kidneys, eyes, lymph nodes and intestines. Data about central nervous system (CNS) involvement in CVID are extremely rare. We aim to describe a case se ries and include an extensive literature review of CNS involvement in CVID to understand the different features and patterns of the disease. (Source: Seminars in Arthritis and Rheumatism)
Source: Seminars in Arthritis and Rheumatism - October 20, 2017 Category: Rheumatology Authors: Catherine E. Najem, Jason Springer, Richard Prayson, Daniel A. Culver, James Fernandez, Jinny Tavee, Rula A. Hajj-Ali Source Type: research

Body composition and clinical symptoms in patients with hip or knee osteoarthritis: Results from the KHOALA cohort
To analyze the associations between body composition, notably low lean mass, and clinical symptoms [pain, physical function, quality of life (QoL)] in patients with symptomatic hip and/or knee OA. (Source: Seminars in Arthritis and Rheumatism)
Source: Seminars in Arthritis and Rheumatism - October 18, 2017 Category: Rheumatology Authors: Cl émence Jeanmaire, Bernard Mazières, Evelyne Verrouil, Lorraine Bernard, Francis Guillemin, Anne-Christine Rat Source Type: research

Factors associated with use of disease modifying agents for rheumatoid arthritis in the National Hospital and Ambulatory Medical Care Survey
We examined the treatment patterns among adults with rheumatoid arthritis (RA) and identified factors influencing access to traditional and biological disease modifying antirheumatic drugs (DMARDs). (Source: Seminars in Arthritis and Rheumatism)
Source: Seminars in Arthritis and Rheumatism - October 18, 2017 Category: Rheumatology Authors: Priyanka Gaitonde, Laura M. Bozzi, Fadia T. Shaya Source Type: research

Body composition and clinical symptoms in patients with hip or knee osteoarthritis: results from the KHOALA cohort
To analyse the associations between body composition, notably low lean mass, and clinical symptoms (pain, physical function, quality of life [QoL]) in patients with symptomatic hip and/or knee OA. (Source: Seminars in Arthritis and Rheumatism)
Source: Seminars in Arthritis and Rheumatism - October 18, 2017 Category: Rheumatology Authors: Jeanmaire Cl émence, Mazières Bernard, Evelyne Verrouil, Bernard Lorraine, Guillemin Francis, Rat Anne-Christine Source Type: research

Factors Associated with Use of Disease Modifying Agents for Rheumatoid Arthritis in the National Hospital and Ambulatory Medical Care Survey
We examined the treatment patterns among adults with rheumatoid arthritis (RA) and identified factors influencing access to traditional and biological disease modifying antirheumatic drugs (DMARDs). (Source: Seminars in Arthritis and Rheumatism)
Source: Seminars in Arthritis and Rheumatism - October 18, 2017 Category: Rheumatology Authors: Priyanka Gaitonde, Laura M. Bozzi, Fadia T. Shaya Source Type: research