Impact of learning curve on perioperative outcomes of off-clamp minimally invasive partial nephrectomy: propensity score matched comparison of outcomes between training versus expert series.
CONCLUSIONS: Our results proved that the impact of learning curve on outcomes of Off C-RPN is negligible after completion of a proper training in minimally invasive surgery. PMID: 32182230 [PubMed - as supplied by publisher] (Source: Minerva Urologica e Nefrologica)
Source: Minerva Urologica e Nefrologica - March 19, 2020 Category: Urology & Nephrology Tags: Minerva Urol Nefrol Source Type: research

Performance of prostate multiparametric MRI for prediction of prostate cancer extraprostatic extension according to NCCN risk categories: implication for surgical planning.
CONCLUSIONS: The performance of mpMRI for prediction of EPE varies greatly between different NCCN risk categories with a low positive predicting value in patients at low to favorable intermediate risk and a low negative predictive value in patients at Unfavorable intermediate to High risk PCa. Given that mpMRI EPE misdiagnosis could have a negative impact on oncological and functional outcomes, NCCN risk categories should be considered when interpreting mpMRI findings in PCa patients. PMID: 32182231 [PubMed - as supplied by publisher] (Source: Minerva Urologica e Nefrologica)
Source: Minerva Urologica e Nefrologica - March 19, 2020 Category: Urology & Nephrology Tags: Minerva Urol Nefrol Source Type: research

Interest and involvement of European urology residents in academic and research activities. An ESRU-ESU-ESUT collaborative study.
Authors: Carrion DM, Rodríguez-Socarrás ME, Mantica G, Pang KH, Esperto F, Mattigk A, Duijvesz D, Vásquez JL, Sebastián JD, Scarpa RM, Papalia R, Porpiglia F, Palou J, G J PMID: 32182232 [PubMed - as supplied by publisher] (Source: Minerva Urologica e Nefrologica)
Source: Minerva Urologica e Nefrologica - March 19, 2020 Category: Urology & Nephrology Tags: Minerva Urol Nefrol Source Type: research

Impact of sarcopenia status of muscle-invasive bladder cancer patients on kidney function after neoadjuvant chemotherapy and post cystectomy complications.
CONCLUSIONS: We observed significant changes in sarcopenic status during NAC. Sarcopenia, estimated by the lumbar SMI measurement, was an independent predictor associated with the risk of renal impairment during NAC and early postoperative complications after RC. PMID: 32083413 [PubMed - as supplied by publisher] (Source: Minerva Urologica e Nefrologica)
Source: Minerva Urologica e Nefrologica - February 22, 2020 Category: Urology & Nephrology Tags: Minerva Urol Nefrol Source Type: research

Percutaneous cryoablation vs SoC in small kidney cancers: the Italian experience.
CONCLUSIONS: According to our analysis, PCA results in an advantageous technique compared to OPN respectively in terms of costs and resource consumption from both the NHS and the hospital perspective. PMID: 32083414 [PubMed - as supplied by publisher] (Source: Minerva Urologica e Nefrologica)
Source: Minerva Urologica e Nefrologica - February 22, 2020 Category: Urology & Nephrology Tags: Minerva Urol Nefrol Source Type: research

All you must know about "Aquablation" procedure for treatment of benign prostatic obstruction: a systematic review of comparative outcomes and critical review of current literature.
CONCLUSIONS: The Aquablation procedure for the treatment of BPO allows high clinical efficacy with an excellent safety profile. For prostate volume 30-80 cc, comparative studies demonstrated that this procedure offers clinical results at least comparable to those of conventional TURP. Latest evidence showed that Aquablation may be used effectively for prostate volumes up to 150 cc. The major strengths are its high-speed resection time, low complication rate, and potential for sexual function preservation. PMID: 32083415 [PubMed - as supplied by publisher] (Source: Minerva Urologica e Nefrologica)
Source: Minerva Urologica e Nefrologica - February 22, 2020 Category: Urology & Nephrology Tags: Minerva Urol Nefrol Source Type: research

Predictive value of preoperative neutrophil-to-lymphocyte ratio in localized prostate cancer: results from a surgical series at a high-volume institution.
CONCLUSIONS: Neutrophil-to-lymphocyte ratio does not have clinical utility for the prediction of adverse pathology and biochemical recurrence. Further research should focus on its value for predicting regional lymph node metastasis. PMID: 32083416 [PubMed - as supplied by publisher] (Source: Minerva Urologica e Nefrologica)
Source: Minerva Urologica e Nefrologica - February 22, 2020 Category: Urology & Nephrology Tags: Minerva Urol Nefrol Source Type: research

A systematic review on imaging-guided metastasis directed therapy for oligorecurrent prostate cancer: revolution or devolution?
CONCLUSIONS: MDT is highly appealing given its potential to delay disease progression and adverse events of systemic therapy. Nonetheless, data remains immature to recommend MDT on a large scale and the selection criteria for patients have yet been defined. Today, MDT should be administered within a clinical trial and results of future research are eagerly awaited. PMID: 32083417 [PubMed - as supplied by publisher] (Source: Minerva Urologica e Nefrologica)
Source: Minerva Urologica e Nefrologica - February 22, 2020 Category: Urology & Nephrology Tags: Minerva Urol Nefrol Source Type: research

Comparative effectiveness of open, laparoscopic and robot-assisted radical cystectomy for bladder cancer: a systematic review and network meta-analysis.
CONCLUSIONS: Current evidence indicates that minimally invasive approaches could be considered as a feasible and safe alternative to ORC when performed by experienced surgeons in selected patients. Notably, RARC may be more suitable for RC with extracorporeal urinary diversion. Larger well-designed trials are still needed to confirm these findings due to the observational nature of most studies. PMID: 32083418 [PubMed - as supplied by publisher] (Source: Minerva Urologica e Nefrologica)
Source: Minerva Urologica e Nefrologica - February 22, 2020 Category: Urology & Nephrology Tags: Minerva Urol Nefrol Source Type: research

Adverse events related to Radium 223 treatment: "real life" data from Eudra-Vigilance database.
CONCLUSIONS: EV database highlights several AEs which are not reported in registry studies as well as different AEs profiles according to age. Clinicians should consider these data when treating patients with Radium 223. PMID: 32083419 [PubMed - as supplied by publisher] (Source: Minerva Urologica e Nefrologica)
Source: Minerva Urologica e Nefrologica - February 22, 2020 Category: Urology & Nephrology Tags: Minerva Urol Nefrol Source Type: research

Hyperbaric Oxygen Therapy reduces mortality in patients with Fournier's gangrene. Results from a multi-institutional observational study.
CONCLUSIONS: HBOT and surgical debridement are independent predictors of reduced FG related mortality. PMID: 32083420 [PubMed - as supplied by publisher] (Source: Minerva Urologica e Nefrologica)
Source: Minerva Urologica e Nefrologica - February 22, 2020 Category: Urology & Nephrology Tags: Minerva Urol Nefrol Source Type: research

The effect of additional drug therapy as metaphylaxis in patients with cystinuria: a systematic review.
CONCLUSIONS: The evidence on benefit of additional drug therapy in patients with cystinuria is scarce. All studied medications showed an effect on stone event and urinary cystine excretion, when used in addition to hyperhydration, alkalization and a diet low on methionine. Based on this systematic review, no drug can be preferred over another. An important aspect in the choice of drug is the risk of side effects. Therefore, the choice of additional drug should be personalized for every patient where the risk of side effects should be taken into consideration. PMID: 32083421 [PubMed - as supplied by publisher] (S...
Source: Minerva Urologica e Nefrologica - February 22, 2020 Category: Urology & Nephrology Tags: Minerva Urol Nefrol Source Type: research

Conservative treatment of upper urinary tract carcinoma in patients with imperative indications.
CONCLUSIONS: Endoscopic management of UTUC in patients with imperative indications appears to be a reasonable alternative to nephroureterectomy. However, stringent endoscopic follow- up is necessary due to the high risk of disease recurrence. PMID: 32083422 [PubMed - as supplied by publisher] (Source: Minerva Urologica e Nefrologica)
Source: Minerva Urologica e Nefrologica - February 22, 2020 Category: Urology & Nephrology Tags: Minerva Urol Nefrol Source Type: research

Retrograde Intra Renal Surgery (RIRS) versus Percutaneous Nephrolithotomy (PCNL) for renal stones > 2cm. A systematic review and meta-analysis.
CONCLUSIONS: RIRS is challenging PCNL for the treatment of large renal stones over 2cm, becoming a safe and effective alternative with a comparable stone free rate, lower complication rate and lower hospitalization time. It is, however, of the uttermost importance to share the treatment decision with the patient due to the possibility of requiring multiple RIRS session to completely clear larger stone burdens. PMID: 32083423 [PubMed - as supplied by publisher] (Source: Minerva Urologica e Nefrologica)
Source: Minerva Urologica e Nefrologica - February 22, 2020 Category: Urology & Nephrology Tags: Minerva Urol Nefrol Source Type: research

Incidence, predictive factors and survival outcomes of incidental prostate cancer in patients who underwent radical cystectomy for bladder cancer.
CONCLUSIONS: iPCa is quite common in our study group and most of cases are organ-confined and well differentiated. Regardless of clinical relevance, iPCa doesn't impact survival outcomes as BCa is driving the prognosis of these patients. PMID: 32026664 [PubMed - as supplied by publisher] (Source: Minerva Urologica e Nefrologica)
Source: Minerva Urologica e Nefrologica - February 8, 2020 Category: Urology & Nephrology Tags: Minerva Urol Nefrol Source Type: research